Area-Based Socioeconomic Inequalities in Colorectal Cancer Survival in Germany: Investigation Based on Population-Based Clinical Cancer Registration

Frontiers in Oncology
Lina JansenGerman Cancer Survival Working Group

Abstract

Background: Socioeconomic inequalities in colorectal cancer survival have been observed in many countries. To overcome these inequalities, the underlying reasons must be disclosed. Methods: Using data from three population-based clinical cancer registries in Germany, we investigated whether associations between area-based socioeconomic deprivation and survival after colorectal cancer depended on patient-, tumor- or treatment-related factors. Patients with a diagnosis of colorectal cancer in 2000-2015 were assigned to one of five deprivation groups according to the municipality of the place of residence using the German Index of Multiple Deprivation. Cox proportional hazards regression models with various levels of adjustment and stratifications were applied. Results: Among 38,130 patients, overall 5-year survival was 4.8% units lower in the most compared to the least deprived areas. Survival disparities were strongest in younger patients, in rectal cancer patients, in stage I cancer, in the latest period, and with longer follow-up. Disparities persisted after adjustment for stage, utilization of surgery and screening colonoscopy uptake rates. They were mostly still present when restricting to patients receiving treatment accord...Continue Reading

References

Jan 1, 1991·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J J Shuster
Apr 25, 2000·BMJ : British Medical Journal·A E CavelaarsJ P Mackenbach
Sep 7, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·L M WoodsM P Coleman
Sep 19, 2007·British Journal of Cancer·L G ShackM P Coleman
Oct 1, 2008·British Journal of Cancer·E MitryM P Coleman
Feb 19, 2009·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Mona JeffreysTony Blakely
Jun 10, 2009·BMC Public Health·Tonje BraatenEiliv Lund
Aug 22, 2009·Social Science & Medicine·Birgitte Lidegaard FrederiksenTorben Jørgensen
Jun 24, 2010·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Mieke J AartsJan Willem W Coebergh
Jul 1, 2010·British Journal of Cancer·B RachetM P Coleman
Apr 1, 2011·The British Journal of Surgery·B BharathanUNKNOWN Northern Region Colorectal Cancer Audit Group (NORCCAG)
Sep 25, 2012·Critical Reviews in Oncology/hematology·Alberto QuagliaUNKNOWN SEIH (Socio-Economic Indicators, Health) Working Group
Mar 27, 2013·Annals of Surgical Oncology·Raymond OliphantUNKNOWN West of Scotland Colorectal Cancer Managed Clinical Network
Nov 22, 2013·International Journal of Cancer. Journal International Du Cancer·Lina JansenUNKNOWN GEKID Cancer Survival Working Group
Apr 1, 2014·Cancer Epidemiology·Alice NenneckeUNKNOWN GEKID cancer survival working group
Apr 15, 2014·Social Science & Medicine·Verena VogtLeonie Sundmacher
Nov 8, 2014·International Journal of Cancer. Journal International Du Cancer·Lina JansenUNKNOWN GEKID Cancer Survival Working Group
May 24, 2016·Oncotarget·Hermann BrennerMichael Hoffmeister
Dec 13, 2016·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Susanne SingerOliver Krauß
Jan 12, 2017·Gut·C M de KlerkUNKNOWN Expert Working Group ‘Coalition to reduce inequities in colorectal cancer screening’ of the World Endoscopy Organization
Jun 24, 2017·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Bernd Holleczek, Alexander Katalinic
Dec 16, 2017·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J M Ordóñez-MenaUNKNOWN Consortium on Health and Ageing: Network of Cohorts in Europe and the United States (CHANCES)
Jun 14, 2018·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·A E VallanceK Walker
Oct 28, 2018·International Journal of Cancer. Journal International Du Cancer·Laure TronUNKNOWN French Network of Cancer Registries (FRANCIM)
Jan 27, 2019·International Journal of Environmental Research and Public Health·Katarina LokarVesna Zadnik
Feb 12, 2020·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Isabelle FinkeUNKNOWN German Cancer Survival Working Group

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Citations

Jul 25, 2021·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Flavie ThomasOlivier Dejardin

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