Areas of uncertainties and unmet needs in bipolar disorders: clinical and research perspectives

The Lancet. Psychiatry
Michael BauerEduard Vieta

Abstract

This Review discusses crucial areas related to the identification, clinical presentation, course, and therapeutic management of bipolar disorder, a major psychiatric illness. Bipolar disorder is often misdiagnosed, leading to inappropriate, inadequate, or delayed treatment. Even when bipolar disorder is successfully diagnosed, its clinical management presents several major challenges, including how best to optimise treatment for an individual patient, and how to balance the benefits and risks of polypharmacy. We discuss the major unmet needs in the diagnosis and management of bipolar disorder in this Review, including improvement of adequate recognition and intervention in at-risk and early-disease stages, identification of reliable warning signs and prevention of relapses in unstable and rapid cycling patients, treatment of refractory depression, and prevention of suicide. Taken together, there are several promising opportunities for improving treatment of bipolar disorder to deliver medical care that is more personalised.

Citations

May 28, 2019·Psychiatry Investigation·Kiwon KimYong Chon Park
Jul 28, 2019·Medicina·Peter DomeXenia Gonda
Dec 1, 2018·European Psychiatry : the Journal of the Association of European Psychiatrists·Estela Jiménez-LópezJosé Luis Santos
Mar 28, 2019·International Journal of Bipolar Disorders·Sameer Jauhar, Allan H Young
Feb 18, 2020·Psychological Medicine·David T LiebersFernando S Goes
Jun 30, 2019·Molecular Psychiatry·Vijayasree V GiridharanTatiana Barichello
Dec 5, 2019·Frontiers in Cellular Neuroscience·Xin-Rui QiLing Shan
Aug 10, 2020·Journal of Human Genetics·Masashi IkedaNakao Iwata
May 20, 2020·Molecular Psychiatry·Chen ZhangMing Li
Aug 13, 2020·Brain Sciences·Joana Silva RibeiroEduard Vieta
Sep 28, 2020·Bipolar Disorders·Emanuel SeverusMichael Bauer
Oct 8, 2020·Research in Psychotherapy : Psychopathology, Process, and Outcome·Marco SolmiCarla Cremonese
Aug 3, 2020·Neuroscience and Biobehavioral Reviews·Mathilde BigotChantal Henry
Jul 23, 2020·Journal of Affective Disorders·Francesco BartoliGiuseppe Carrà
Jan 7, 2021·SAGE Open Medicine·Siqi XueBenoit H Mulsant
Feb 14, 2021·Journal of Affective Disorders·Bruno EtainJan Scott
Jan 19, 2021·Acta Psychiatrica Scandinavica·M Bauer
Dec 9, 2020·Journal of Korean Medical Science·Yoojin SongYong Min Ahn
Jun 17, 2020·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Mirko ManchiaUNKNOWN European College of Neuropsychopharmacology (ECNP) Bipolar Disorders Network
May 21, 2021·Journal of Cellular and Molecular Medicine·Jianbo LaiShaohua Hu
Aug 13, 2021·Frontiers in Psychiatry·Peifen ZhangShaohua Hu
Aug 28, 2021·Journal of Personalized Medicine·Eva M Sánchez-MorlaElena Garcia-Martin

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