PMID: 18705550Aug 19, 2008Paper

Argatroban in short-term percutaneous ventricular assist subsequent to heparin-induced thrombocytopenia.

The Journal of Extra-corporeal Technology
David P WebbJohn G Byrne

Abstract

Heparin-induced thrombocytopenia paradoxically is a transient pro-thrombotic disorder triggered by heparin exposure. If not treated appropriately, it can be life threatening because of its related thromboembolic complications. In particular, it presents a unique challenge in patients needing extracorporeal life support, because anticoagulation is essential for safe management. This case report describes the safe, efficacious use of Argatroban during short-term support of a patient with a percutaneously inserted left ventricular assist TandemHeart device.

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