Argentine references for the assessment of body proportions from birth to 17 years of age

Archivos argentinos de pediatría
Mariana del PinoVirginia Fano

Abstract

Abnormal body proportions may indicate skeletal disorders; therefore, their detection has great clinical significance. To estimate centiles for head circumference/height (HC/H) and sitting height/height (SH/H) ratios, and assess their diagnostic usefulness among a group of children with skeletal dysplasia. Centiles 3, 10, 25, 50, 75, 90 and 97 for HC/H and SH/H ratios were estimated with the LMS method using Box-Cox transformation to normalize data distribution for each age. Q-Q plot tests were applied to evaluate normality of residuals and the Q test to calculate goodness-of-fit. The sample included 4818 girls and4803 boys, all healthy, between 0-17 years old. The median of the SH/H ratio for each age decreased from 0.67 at birth to 0.57 at age 4. At 12 years of age, values reached 0.52 and 0.53 for males and females, respectively, remaining unchanged until age 17. The median of the HC/H ratio decreased from 0.45 at 6 years old to 0.34 at 17 years old for both sexes. Z-scores for SH/H among 20 children diagnosed with hypochondroplasia were better at showing abnormal proportions than the SH/H ratio not adjusted by age. Estimated centiles for HC/H and SH/H ratios show that the most dramatic changes in body proportions occur in t...Continue Reading

Citations

Feb 10, 2018·American Journal of Medical Genetics. Part a·Mariana Del PinoVirginia Fano
Oct 20, 2018·Journal of Pediatric Endocrinology & Metabolism : JPEM·María Alejandra ArenasVirginia Fano
May 1, 2021·Children·Ryoji AokiIchiro Morioka
Jun 20, 2021·Journal of Pediatric Endocrinology & Metabolism : JPEM·María Alejandra ArenasVirginia Fano

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