Arginine-containing desensitizing toothpaste for the treatment of dentin hypersensitivity: a meta-analysis

Clinical, Cosmetic and Investigational Dentistry
Zheng-Yan YangZhi Zhou

Abstract

To estimate the effect of arginine-containing desensitizing toothpaste on dentin hypersensitivity (DH). Databases including China National Knowledge Infrastructure, VIP Database for Chinese Technical Periodicals, China Biology Medicine disc, Wangfang Data, PubMed, Web of Science, and Cochrane Trials Register were searched, and Google was used as a supplementary tool to search for information through February 2014. Randomized controlled trials (RCTs) of the treatment of DH with arginine-containing toothpaste were included. Relevant information was extracted, and a quality evaluation was performed. Meta-analyses were performed using RevMan 5.2 software. Eighteen RCTs with 1,423 patients were included. The results of the meta-analyses demonstrated that at days 0 and 3; weeks 2, 4, and 8; and more than 12 weeks, arginine-containing toothpaste led to significantly improved results on the tactile sensitivity test (standardized mean difference [SMD] =1.95, 95% confidence interval [CI] [1.14, 2.76]) and the air-blast test (SMD =-1.60, 95% CI [-2.14, -1.05]) at 4 weeks and the tactile sensitivity test (SMD =2.01, 95% CI [1.41, 2.61]) and the air-blast test (SMD =-1.41, 95% CI [-1.83, -0.98]) at 8 weeks compared to toothpastes containing...Continue Reading

Citations

May 13, 2021·Clinical Oral Investigations·Raquel Marianna LopesAna Cecilia Correa Aranha

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RevMan
PRISMA
Cochrane Reviewers Handbook

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