PMID: 5903088Jan 1, 1966

Arginine metabolism in Halobacterium salinarium, an obligately halophilic bacterium

Journal of Bacteriology
I E Dundas, H O HALVORSON

Abstract

Dundas, Ian E. D. (University of Illinois, Urbana), and H. Orin Halvorson. Arginine metabolism in Halobacterium salinarium, an obligately halophilic bacterium. J. Bacteriol. 91:113-119. 1966.-Arginine was shown to be essential for growth of Halobacterium salinarium strain 1 in a chemically defined medium. Citrulline was the only compound which could substitute for arginine without affecting growth. Resting cells of H. salinarium converted arginine to citrulline and citrulline to ornithine. Cells grown in an arginine-free medium with C(14)-ureido-labeled citrulline incorporated the isotope mainly into the arginine of their proteins. The enzymes arginine desimidase and ornithine transcarbamylase were found and studied in cell-free extracts of H. salinarium. Experiments indicated that arginine was degraded in H. salinarium by arginine desimidase to citrulline, and that citrulline was further degraded by ornithine transcarbamylase to carbamyl phosphate and ornithine. Synthesis of arginine from citrulline seems to occur via the formation of argininosuccinic acid.

Citations

Nov 1, 1975·Bulletin of Environmental Contamination and Toxicology·C L NobleW L Blevins
Apr 30, 2009·PLoS Computational Biology·Orland GonzalezDieter Oesterhelt
Mar 25, 2016·PloS One·Cherryl O TalaueDieter Oesterhelt
May 23, 1972·European Journal of Biochemistry·I E Dundas
Oct 1, 1970·European Journal of Biochemistry·I E Dundas
Feb 15, 2000·Molecular Microbiology·M V Kokoeva, D Oesterhelt
Nov 15, 2008·Molecular Microbiology·Torsten Hechler, Felicitas Pfeifer
Jan 24, 2008·Molecular BioSystems·Orland GonzalezDieter Oesterhelt
Mar 1, 1971·The Journal of Membrane Biology·M GinzburgB Z Ginzburg
Oct 13, 2012·Environmental Microbiology·Sabrina FrölsFelicitas Pfeifer

Related Concepts

Adenine Nucleotides
Arginine hydrochloride
Bacterial Proteins
Citrulline
Halobacterium
Ornithine Carbamoyltransferase
Sodium Chloride, (24)NaCl
Ureohydrolases

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