Argosomes: intracellular transport vehicles for intercellular signals?

Science's STKE : Signal Transduction Knowledge Environment
Jan L Christian

Abstract

Cell clusters in the immature tissues of developing organisms create morphogen gradients that guide cellular differentiation into specific cell fates. Although the process of simple diffusion in gradient establishment has been well studied, there are other mechanisms by which cells establish morphogen gradients. Christian discusses the recent findings that morphogens may establish gradients through the use of plasma membrane-containing exovesicles, termed "argosomes."

References

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Citations

Feb 22, 2005·Current Opinion in Neurobiology·Charles L Howe, William C Mobley
Jul 6, 2010·Developmental Biology·Kyung-Hwa Kang, Ethan Bier
Feb 11, 2003·Cell Structure and Function·Graça RaposoMichael S Marks

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