Aripiprazole for late-life schizophrenia

Clinical Interventions in Aging
Jeffrey Rado, Philip G Janicak

Abstract

Antipsychotics are frequently used in elderly patients to treat a variety of conditions, including schizophrenia. While extensively studied for their impact in younger populations, there is comparatively limited evidence about the effectiveness of these agents in older patients. Further complicating this situation are the high co-morbidity rates (both psychiatric and medical) in the elderly; age-related changes in pharmacokinetics leading to a heightened proclivity for adverse effects; and the potential for multiple, clinically relevant drug interactions. With this background in mind, we review diagnostic and treatment-related issues specific to elderly patients suffering from schizophrenia and other psychotic conditions, focusing on the potential role of aripiprazole.

References

Jul 8, 2014·International Journal of Psychiatry in Clinical Practice·Gul EryilmazÖzgür Yorbik
Sep 29, 2020·Internal Medicine Journal·Michael M C WongK Y Mak

Citations

Nov 1, 1996·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·P V RabinsJ Cook
Sep 4, 1998·Psychiatry Research·T L PattersonDilip V Jeste
Mar 13, 1999·The Journal of Clinical Psychiatry·E HowanitzM F Losonczy
Aug 14, 1999·Journal of Geriatric Psychiatry and Neurology·J D EvansDilip V Jeste
Sep 9, 2000·Schizophrenia Research·U OsbyP Sparén
Oct 27, 2001·International Journal of Aging & Human Development·N H Solano, S K Whitbourne
Nov 12, 2003·The International Journal of Neuropsychopharmacology·Siegfried KasperTeresa A Pigott
Nov 18, 2003·International Journal of Geriatric Psychiatry·J S KennedyA Breier
Nov 25, 2003·The Journal of Clinical Psychiatry·Teresa A PigottAripiprazole Study Group
Jan 30, 2004·Diabetes Care·American Diabetes AssociationNorth American Association for the Study of Obesity
Feb 8, 2005·Schizophrenia Research·Matthew M Kurtz
Mar 7, 2007·International Journal of Geriatric Psychiatry·Bret RutherfordSteven Roose
Apr 17, 2007·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Milena Pereira Pondé, Camila Marinho Novaes
Jun 26, 2007·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Sanjay GuptaKay Schultz
Mar 4, 2008·The Journal of Clinical Psychiatry·Martha SajatovicWilliam J Meyer
Jul 2, 2008·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Joel E StreimWilliam H Carson
Nov 1, 2008·Clinical Psychology Review·Katherine Berry, Christine Barrowclough
Apr 3, 2009·Journal of Psychiatric Practice·Kim C ColeyTanya J Fabian

Related Concepts

Antipsychotic Effect
Morbidity Aspects
Schizophrenia
Piperazines
Senility
Aripiprazole
Adverse Effects
Antipsychotic Agents
OPC 14597
Drug Interactions

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