Arm length is associated with type 2 diabetes mellitus in Japanese-Americans.

Diabetologia
M M SmitsS E Kahn

Abstract

The aim of the study was to examine the association of type 2 diabetes mellitus with arm length as a marker for early life environment and development. This was a cross-sectional analysis of 658 second- and third-generation Japanese-Americans (349 men and 309 women). Different arm length (total, upper and forearm length) and leg length (total and lower leg length) measurements were performed. Type 2 diabetes was defined by the use of hypoglycaemic medication, fasting plasma glucose (FPG) ≥ 7 mmol/l or glucose at 2 h ≥ 11.1 mmol/l during an OGTT. Persons meeting the criteria for impaired glucose tolerance were excluded from these analyses (FPG <7 mmol/l and 2 h glucose during an OGGT <11.1 but ≥ 7.8 mmol/l). Multivariable logistic regression was used to estimate associations between prevalence of diabetes and limb length while adjusting for possible confounders. A total of 145 individuals had diabetes. On univariate analysis, arm and leg length were not associated with diabetes. After adjustment for age, sex, computed tomography-measured intra-abdominal fat area, height, weight, smoking status and family history of diabetes, total arm length and upper arm length were inversely related to diabetes (OR for a 1 SD increase 0.49, 95...Continue Reading

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Oct 15, 1991·Biochemical and Biophysical Research Communications·P R GanzF Luison
Apr 10, 2019·Journal of Epidemiology and Community Health·Sarita ShresthaJennifer L Baker
Mar 18, 2021·Current Diabetes Reports·Nadia Markie Sneed, Shannon A Morrison

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