AromaDb: A Database of Medicinal and Aromatic Plant's Aroma Molecules With Phytochemistry and Therapeutic Potentials

Frontiers in Plant Science
Yogesh KumarFeroz Khan

Abstract

In traditional, herbal medicine, and aromatherapy, use of essential oils and their aroma compounds have been known since long, for the management of various human diseases. The essential oil is a mixture of highly complex, naturally occurring volatile aroma compounds synthesized by medicinal and aromatic plants as secondary metabolites. Essential oils widely used in pharmaceutical, cosmetic, sanitary, food industry and agriculture for their antibacterial, antiviral, antifungal, antiparasitic, insecticidal, anticancer, neuroprotective, psychophysiological, and anti-aging activities. Moreover, volatile aroma compounds comprise a chemically diverse class of low molecular weight organic compounds with significant vapor pressure. However, aroma compounds produced by plants, mainly attract pollinators, seed dispersers and provide defense against pests or pathogens. However, in humans, about 300 active olfactory receptor genes are involved to detect thousands of different aroma compounds and modulates expression of different metabolic genes regulating human psychophysiological activity, brain function, pharmacological signaling, and therapeutic potential. Keeping in mind this importance, present database, namely, AromaDb (http://bioin...Continue Reading

References

Jul 20, 2006·Journal of Agricultural and Food Chemistry·Felix Frauendorfer, Peter Schieberle
Mar 16, 2007·Proceedings of the National Academy of Sciences of the United States of America·Martin Heil, Juan Carlos Silva Bueno
Oct 22, 2008·Nucleic Acids Research·Mathias DunkelRobert Preissner
Jun 6, 2009·Nucleic Acids Research·Yanli WangStephen H Bryant
Dec 24, 2014·Database : the Journal of Biological Databases and Curation·Sangita KumariGitanjali Yadav

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Citations

Jan 24, 2019·Phytotherapy Research : PTR·Ahmad MouwakehGabriella Spengler
Feb 28, 2020·Experimental and Therapeutic Medicine·Changhwan AhnEui-Bae Jeung
Jul 25, 2020·Briefings in Bioinformatics·Xiaoxia MaTian Xie
Sep 10, 2020·Data in Brief·Yeong-Min YooEui-Bae Jeung
Jan 16, 2021·Journal of Chemical Information and Modeling·Anju SharmaPritish Kumar Varadwaj
Jun 8, 2021·Briefings in Bioinformatics·Yin JinBao-An Song
Aug 14, 2021·Critical Reviews in Food Science and Nutrition·José Fernando Rinaldi de AlvarengaJarlei Fiamoncini

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Software Mentioned

JSME
Apache HTTP
AromaDbdatabase
JME
SMILES code ( Simplified Molecular Input Line Entry System
JSME ( JavaScript Molecular Editor
ChemAxon
ACToR
MOL
JSmol

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