Mar 19, 1976

Aromatic amino acid biosynthesis in Alcaligenes eutrophus H 16 III. Properites and regulation of anthranilate synthase

Archives of Microbiology
C G FriedrichH G Schlegel


Properties and regulation of anthranilate synthase from Alcaligenes eutrophus H 16 were investigated. Anthranilate synthase was partially purified from crude extracts by affinity chromatography on tryptophan-substituted Sepharose, and was used for kinetic measurements. During the purification procedure the enzyme was stabilized by 50 mM L-glutamine or during chromatography on DEAE- cellulose and Sephadex G-200 with 30% glucerol, respectively.

Mentioned in this Paper

Sephadex G 200
Anthranilate Phosphoribosyltransferase
Amino Acid Biosynthesis
Purification Aspects

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