Aromatic L-amino acid decarboxylase-immunoreactive neurons in and around the cerebrospinal fluid-contacting neurons of the central canal do not contain dopamine or serotonin in the mouse and rat spinal cord

Brain Research
I NagatsuT Nagatsu

Abstract

Using a specific antibody against each of the 4 catecholamine-synthesizing enzymes, dopamine or serotonin, we compared the localization of these substances in rat and mouse spinal cord with two kinds of fixative, such as paraformaldehyde and glutaraldehyde, and two types of sectioning technique, i.e. cryostat and microslicer. In this study, we demonstrated aromatic L-amino acid decarboxylase (AADC)-like immunoreactivity (LI) in cerebrospinal fluid (CSF)-contacting neurons for the first time in the mouse. These cells and some AADC-immunoreactive cells localized outside the subependymal layer of mouse and rat spinal cord did not show tyrosine hydroxylase-, serotonin- and dopamine-LI with and without colchicine treatment.

References

Sep 1, 1977·Analytical Biochemistry·R T BorchardtG L Grunewald
Dec 5, 1975·Brain Research·J A ZivinI J Kopin
Aug 1, 1987·Journal of Neurochemistry·J L ChagnaudM Geffard
Jan 1, 1973·International Review of Cytology·B Vigh, I Vigh-Teichmann
Aug 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·G TeitelmanD J Reis
Apr 20, 1982·The Journal of Comparative Neurology·C C LamotteN C de Lanerolle
Jul 1, 1982·Brain Research Bulletin·G SkagerbergR H Schmidt
Jan 1, 1964·Acta Physiologica Scandinavica·A CARLSSONN A HILLARP
Jun 1, 1952·The Journal of Comparative Neurology·B REXED

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Citations

Jan 1, 1995·Journal of Neural Transmission. General Section·I NagatsuT Nagatsu
Jan 1, 1992·Virchows Archiv. A, Pathological Anatomy and Histopathology·N KimuraH Nagura
Sep 27, 2006·Pituitary·Joseph E Ippolito
Jan 1, 1989·Pharmacology & Therapeutics·C Bell
Nov 1, 1994·Journal of the Autonomic Nervous System·M SuzukiI Nagatsu
Feb 5, 1993·Neuroscience Letters·M TakadaT Hattori
May 23, 1994·Neuroscience Letters·F R CagampangS Inouye
Sep 30, 2000·Brain Research. Brain Research Reviews·W J Smeets, A González
Aug 29, 1997·Neuroscience Letters·K IkemotoI Nagatsu
Aug 26, 2003·Legal Medicine·Keiko IkemotoKatsuji Nishi

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