Arrhythmias and left ventricular hypertrabeculation /noncompaction

Current Pharmaceutical Design
Claudia Stöllberger, Josef Finsterer

Abstract

Arrhythmias in left ventricular hypertrabeculation/noncompaction (LVHT) comprise sustained or non-sustained ventricular tachycardia (VT) (n=135), atrial fibrillation (AF) (n=96) AV block (n=55) and QT prolongation (n=47). The prevalence differs between children and adults. In children most frequent are WPW-syndrome (n=24), AV block (n=24), VT (n=17) and bradycardia (n=15). In adults most frequent arrhythmias are VT (n=118), AF (n=95), QT prolongation (n=42) and AV block (n=31). Some arrhythmias are more frequently reported in children than in adults like WPW-syndrome (24 vs. 17 patients), second-degree AV block (4 vs. 0 patients), bradycardia (15 vs. 3 patients) and ventricular fibrillation (VF) (9 vs. 5 patients). There are nearly no pediatric cases with AF (1 vs. 95 patients). In 120 patients implantable cardioverters/defibrillators have been implanted for primary or secondary prevention of sudden cardiac death. The pathomechanisms of arrhythmias in LVHT are largely unknown, especially if patients with LVHT and neuromuscular disorders are more prone to arrhythmias than patients without. There is a need to clarify risk factors for VT or VF because 19% of LVHT patients with VT or VF have a normal systolic function and demonstra...Continue Reading

Citations

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Apr 15, 2014·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Claudia StöllbergerJosef Finsterer
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Nov 15, 2011·International Journal of Cardiology·Josef Finsterer, Claudia Stöllberger
Jun 10, 2011·International Journal of Cardiology·Claudia StöllbergerJosef Finsterer
Apr 5, 2014·International Journal of Cardiology·Giuseppe Mario CalvagnaFrancesco Patanè
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Jan 4, 2021·Pediatric Cardiology·Juan VillafaneDevyani Chowdhury
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