Arsenic in drinking water and adverse birth outcomes in Ohio

Environmental Research
Kirsten AlmbergLeslie Thomas Stayner

Abstract

Arsenic in drinking water has been associated with adverse reproductive outcomes in areas with high levels of naturally occurring arsenic. Less is known about the reproductive effects of arsenic at lower levels. This research examined the association between low-level arsenic in drinking water and small for gestational age (SGA), term low birth weight (term LBW), very low birth weight (VLBW), preterm birth (PTB), and very preterm birth (VPTB) in the state of Ohio. Exposure was defined as the mean annual arsenic concentration in drinking water in each county in Ohio from 2006 to 2008 using Safe Drinking Water Information System data. Birth outcomes were ascertained from the birth certificate records of 428,804 births in Ohio from the same time period. Multivariable generalized estimating equation logistic regression models were used to assess the relationship between arsenic and each birth outcome separately. Sensitivity analyses were performed to examine the roles of private well use and prenatal care utilization in these associations. Arsenic in drinking water was associated with increased odds of VLBW (AOR 1.14 per µg/L increase; 95% CI 1.04, 1.24) and PTB (AOR 1.10; 95% CI 1.06, 1.15) among singleton births in counties where...Continue Reading

Citations

Mar 21, 2019·PloS One·Tesfahun Mulatu WachamoAsmamaw Demis Bizuneh
Jan 16, 2021·International Journal of Environmental Research and Public Health·Rasheda KhanamAbdullah H Baqui
Mar 12, 2021·Journal of Exposure Science & Environmental Epidemiology·Alison K KrajewskiJyotsna S Jagai
May 26, 2021·The Science of the Total Environment·Jochen BundschuhAbhijit Mukherjee
Jun 21, 2021·Environment International·Mohammad L RahmanAndres Cardenas
Oct 19, 2021·The Cochrane Database of Systematic Reviews·Sajin BaePatrick J Stover

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