Arsenic transformations and biomarkers in meadow voles (Microtus pennsylvanicus) living on an abandoned gold mine site in Montague, Nova Scotia, Canada

The Science of the Total Environment
Jared R SaundersKenneth J Reimer

Abstract

Arsenic is one of the most widely encountered environmental contaminants because of a number of anthropogenic sources; in Canada the main anthropogenic release of arsenic is from mine tailings ponds. The present study is part of a series of studies to measure chemical and biological effects of exposure for meadow voles (Microtus pennsylvanicus) living on arsenic contaminated sites. Two additional objectives were addressed in the present study: the effect of higher arsenic concentrations compared with previous studies, and the comparison of chemical speciation and biological effects. To obtain the higher environmental concentrations, specimens were collected from a former gold mining site in Montague, NS that contains highly elevated concentrations of arsenic in soils and plants. Meadow voles were collected and their tissues were analyzed for total arsenic to measure uptake, and arsenic speciation to examine the chemical effects of the high arsenic exposure. In addition to the arsenic analysis, a biomonitoring study was undertaken to examine the sub-cellular effects in meadow voles resulting from the elevated arsenic exposure. Meadow voles living on the contaminated site had substantially higher concentrations of total arsenic t...Continue Reading

References

Jun 1, 1997·Mutation Research·M M MooreC L Doerr
Aug 14, 1998·Bulletin of Environmental Contamination and Toxicology·R D Hood
Nov 23, 2000·Chemical Research in Toxicology·A Sampayo-ReyesH V Aposhian
Dec 13, 2000·Mutation Research·G Krishna, M Hayashi
Oct 16, 2001·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·M MahboobA T Khan
Oct 17, 2001·Toxicology and Applied Pharmacology·D J ThomasS Lin
Mar 26, 2002·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Iván Csanaky, Zoltán Gregus
Aug 28, 2002·Journal of Environmental Monitoring : JEM·Caroline J LangdonJanet Cotter-Howells
Jul 28, 2004·Toxicology and Applied Pharmacology·Hideki WanibuchiShoji Fukushima
Jan 26, 2006·Basic & Clinical Pharmacology & Toxicology·Somia BashirT D Dogra
May 12, 2006·Journal of Occupational and Environmental Medicine·Craig SteinmausAllan H Smith
Sep 28, 2006·Annual Review of Pharmacology and Toxicology·Yoshito Kumagai, Daigo Sumi
Dec 25, 2007·Analytica Chimica Acta·Zdenka SlejkovecPeter Cernelc
Dec 5, 2008·Journal of the American Chemical Society·Thanh T NguMartin J Stillman
Apr 22, 2009·Molecular Nutrition & Food Research·Xiufen LuX Chris Le
Aug 14, 2009·Environmental Science & Technology·Maeve M MoriartyKenneth J Reimer
Aug 14, 2009·The Science of the Total Environment·Jared R SaundersKenneth J Reimer

❮ Previous
Next ❯

Citations

Nov 15, 2011·The Science of the Total Environment·Jared R SaundersKenneth J Reimer
Nov 19, 2013·The Science of the Total Environment·Séverine DrouhotRenaud Scheifler
Jun 12, 2012·Environmental Pollution·Mark ButtonKenneth J Reimer
Nov 29, 2014·Environmental Science and Pollution Research International·P Abad-ValleA Murciego
Apr 21, 2011·Journal of Environmental Monitoring : JEM·Jared R SaundersKenneth J Reimer
Oct 12, 2011·Archives of Environmental Contamination and Toxicology·Maeve M MoriartyKenneth J Reimer
Jul 14, 2021·Environmental Science and Pollution Research International·Thi Anh Thu TranDongli Liang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.