Apr 29, 2016

Artefactual origin of biphasic cortical spike-LFP correlation

BioRxiv : the Preprint Server for Biology
Michael Okun

Abstract

Electrophysiological data acquisition systems introduce various distortions into the signals they record. While such distortions were discussed previously, their effects are often not appreciated. Here I show that the biphasic shape of cortical spike-triggered LFP average (stLFP), reported in multiple studies, is likely an artefact introduced by high-pass filter of the neural data acquisition system when the actual stLFP has a single trough around the zero lag.

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