Artemisia annua L. as a plant with potential use in the treatment of acanthamoebiasis

Parasitology Research
Monika DerdaAgnieszka Wojtkowiak-Giera

Abstract

The treatment of acanthamoebiasis is a great problem. Most cerebral invasions end with death, and the treatment of ocular invasions is usually long-lasting and not very effective. Numerous plant extracts and substances isolated from plants, which are effective against trophozoites or cysts, have been studied in the treatment of acanthamoebiasis. However, no agents that are simultaneously effective against both developing forms of amoebae have been discovered yet. It seems that such a plant which fulfils both tasks is Artemisia annua L. Our studies showed that water, alcohol and chloroform extracts from the herb A. annua L. can be applied in general and local treatment or in combined therapy with antibiotics in the treatment of acanthamoebiasis. Extracts from this plant show not only in vitro but also in vivo effects. Studies carried out on experimental animals infected with amoebae show that the application of these extracts significantly prolongs the survival of the animals.

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Citations

Jan 27, 2017·Parasitology Research·Edward HadaśMarcin Cholewiński
Dec 21, 2017·Evidence-based Complementary and Alternative Medicine : ECAM·Jun HuangJinhua Shen
Apr 5, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Małgorzata KikowskaBarbara Thiem
Sep 30, 2020·Progress in Biomaterials·Fatemeh Sadat MirbehbahaniAzadeh Asefnejad
Jul 19, 2020·International Journal of Molecular Sciences·Axelle Septembre-MalaterrePhilippe Gasque
Jul 27, 2021·International Journal of Dermatology·Kesrin AmraFateh Khan
Apr 24, 2020·Infectious Disorders Drug Targets·Tooran NayeriFatemeh Ghaffarifar

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