Artemisia pollen is the main vector for airborne endotoxin

The Journal of Allergy and Clinical Immunology
Jose OterosJeroen Buters

Abstract

Endotoxin (LPS) released from gram-negative bacteria causes strong immunologic and inflammatory effects and, when airborne, can contribute to respiratory conditions, such as allergic asthma. We sought to identify the source of airborne endotoxin and the effect of this endotoxin on allergic sensitization. We determined LPS levels in outdoor air on a daily basis for 4 consecutive years in Munich (Germany) and Davos (Switzerland). Air was sampled as particulate matter (PM) greater than 10 μm (PM > 10) and PM between 2.5 and 10 μm. LPS levels were determined by using the recombinant Factor C assay. More than 60% of the annual endotoxin exposure was detected in the PM > 10 fraction, showing that bacteria do not aerosolize as independent units or aggregates but adhered to large particles. In Munich 70% of annual exposure was detected between June 12th and August 28th. Multivariate modeling showed that endotoxin levels could be explained by phenological parameters (ie, plant growth). Indeed, days with high airborne endotoxin levels correlated well with the amount of Artemisia pollen in the air. Pollen collected from plants across Europe (100 locations) showed that the highest levels of endotoxin were detected on Artemisia vulgaris (mu...Continue Reading

Citations

Feb 19, 2020·Contact Dermatitis·Panqian WuYuye Li
Jul 28, 2020·Frontiers in Immunology·Anna I JoubertMartin Himly
Feb 12, 2019·The Journal of Clinical Investigation·Liza Bronner MurrisonGurjit K Khurana Hershey
Sep 5, 2020·Clinical and Translational Allergy·Lisa PointnerLorenz Aglas
Oct 25, 2020·The Science of the Total Environment·Susanne DunkerJan-Christoph Simon
Nov 29, 2020·Environmental Pollution·José María CorderoRafael Borge

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
Can ZhaoGuang-fa Wang
© 2022 Meta ULC. All rights reserved