Arterial and portal venous liver perfusion using selective spin labelling MRI

European Radiology
Hanke J SchalkxMarijn van Stralen

Abstract

To investigate the feasibility of selective arterial and portal venous liver perfusion imaging with spin labelling (SL) MRI, allowing separate labelling of each blood supply. The portal venous perfusion was assessed with a pulsed EPISTAR technique and the arterial perfusion with a pseudo-continuous sequence. To explore precision and reproducibility, portal venous and arterial perfusion were separately quantified in 12 healthy volunteers pre- and postprandially (before and after meal intake). In a subgroup of 6 volunteers, the accuracy of the absolute portal perfusion and its relative postprandial change were compared with MRI flow measurements of the portal vein. The portal venous perfusion significantly increased from 63 ± 22 ml/100g/min preprandially to 132 ± 42 ml/100g/min postprandially. The arterial perfusion was lower with 35 ± 22 preprandially and 22 ± 30 ml/100g/min postprandially. The pre- and postprandial portal perfusion using SL correlated well with flow-based perfusion (r(2) = 0.71). Moreover, postprandial perfusion change correlated well between SL- and flow-based quantification (r(2) = 0.77). The SL results are in range with literature values. Selective spin labelling MRI of the portal venous and arterial blood s...Continue Reading

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Citations

May 8, 2021·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Yu OshimaKojiro Taura
Aug 29, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Tobit FühresFrederik Bernd Laun
Sep 16, 2021·American Journal of Physiology. Gastrointestinal and Liver Physiology·Farid ZreikGiris Jacob

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