PMID: 11913610Mar 27, 2002Paper

Arterial elasticity among normotensive subjects and treated and untreated hypertensive subjects: influence of race

Ethnicity & Disease
L Michael PrisantDena Jupin

Abstract

To determine arterial elasticity in normotensives and in treated and untreated hypertensive Black and White subjects. A prospective multicenter, controlled clinical trial evaluated large (C-) and small (C2) artery elasticity indices among 3 groups: 1) normotensive subjects with or without a family history of hypertension; 2) controlled and treated hypertensive subjects; and 3) untreated and uncontrolled hypertensive subjects. Blood pressure was measured using a mercury manometer and arterial compliance or elasticity was determined using a CVProfilor DO-2020 CardioVascular Profiling System (Hypertension Diagnostics, Inc, Eagan, Minn). These parameters were measured in triplicate 3 minutes apart in a random sequence, with the patient in a supine position. Two-way ANOVA was used for statistical evaluation. One hundred seventy eight subjects met stratification and enrollment criteria. The mean age was 46 years. 109 were White and 69 were Black. [table: see text] Small and large arterial elasticity indices are reduced as hypertension status worsens. Age and height were important covariates of C1 and C2. Race was not found to be a significant predictor of either C1 or C2. Large and small artery elasticity indices do not differ betwee...Continue Reading

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