PMID: 8946345Dec 1, 1996Paper

Arterial input functions from MR phase imaging

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Erbil Akbudak, T E Conturo

Abstract

A method is presented for obtaining high-sensitivity arterial input functions following bolus intravenous contrast agent administration. Arterial contrast agent is monitored by phase reconstruction of single-shot echo-planar images. During bolus injections of a gadolinium (Gd) agent in a baboon, data were acquired at the mid-abdominal aorta, and magnitude and phase-shift images were reconstructed. Pairwise image subtraction was used to minimize phase aliasing. The phase-based method is shown to have a significant potential improvement in sensitivity compared to the magnitude approach. The phase method also has a general linear response to concentration. This method may have potential utility in quantitative imaging of blood flow and contrast agent kinetics.

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Citations

Mar 10, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·M J van OschM A Viergever
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