Arterial reservoir characteristics and central-to-peripheral blood pressure amplification in the human upper limb

Journal of Hypertension
Xiaoqing PengJames E Sharman

Abstract

Arterial reservoir characteristics are related to blood pressure (BP) and independently predict cardiovascular events. It is unknown if arterial reservoir characteristics are modified from the central-to-peripheral large arteries and whether there is a contributory role to BP amplification. The aim of this study was to assess central-to-peripheral changes in arterial reservoir characteristics and determine associations with BP. Reservoir pressure (RP) and excess pressure (XSP) were derived from intra-arterial BP waveforms among 51 participants (aged 63 ± 13 years, 63% men) undergoing clinically indicated cardiac angiography. BP waveforms were recorded in the ascending aorta, brachial (mid-humerus) and radial (wrist) arteries via catheter pull-back. There was no significant difference in RP between arterial sites (54 ± 15, 53 ± 15 and 52 ± 17 mmHg for the aorta, brachial and radial artery, respectively; P = 0.68). Conversely, XSP increased stepwise from the aorta to the brachial and radial arteries (24 ± 11, 42 ± 14 and 53 ± 16 mmHg; P < 0.001), as did SBP (134 ± 18, 141 ± 16 and 146 ± 19 mmHg; P = 0.004). There were highly significant associations between RP and SBP at all arterial sites (r = 0.821, 0.649 and 0.708; P < 0.001 f...Continue Reading

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Citations

Nov 20, 2018·The Journal of Clinical Hypertension·Xiaoqing PengJames E Sharman
Sep 21, 2018·Journal of Hypertension·Dean S PiconeJames E Sharman
Mar 25, 2019·Hypertension·Matthew K ArmstrongJames E Sharman
Jun 22, 2019·Journal of the American Heart Association·Catherine FortierMohsen Agharazii
Feb 2, 2020·American Journal of Hypertension·Matthew K ArmstrongJames E Sharman
Sep 23, 2020·Current Hypertension Reports·Dean S PiconeJames E Sharman
May 31, 2019·Journal of Hypertension·Przemyslaw GuzikAndrzej Wykretowicz
May 6, 2020·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Alun D Hughes, Kim H Parker
Aug 13, 2017·Current Hypertension Reports·Bernhard Hametner, Siegfried Wassertheurer
Sep 26, 2020·Frontiers in Physiology·Jonathan P MynardJoseph J Smolich
Nov 10, 2020·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Xiaoqing PengJames E Sharman
Oct 9, 2020·Journal of Hypertension·Matthew K ArmstrongJames E Sharman
Mar 23, 2021·Journal of Human Hypertension·Matthew K ArmstrongJames E Sharman

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