PMID: 16623110Apr 21, 2006Paper

Arterial stiffness--pathophysiological significance and practical aspects of assessment

Przegla̧d lekarski
Paweł StróźeckiRenata Naruszewicz

Abstract

Arterial stiffness is a dynamic property which depends on structure and function of arteries. Arterial stiffness progresses with age and it is an important factor leading to increase of systolic and pulse pressure and decrease in diastolic blood pressure. Increased arterial stiffness was also found in hypertension, chronic renal failure and diabetes. Arterial stiffness is an independent prognostic factor of mortality in hypertension and end-stage renal disease. Arterial stiffening leads to cardiovascular complications such as left ventricular hypertrophy. Many methods to assess different aspects of arterial stiffness: systemic, regional and local were developed. Various indicies of arterial stiffness were defined and are used in clinical investigations. Arterial stiffness is a dynamic parameter. Decrease in blood pressure leads to decrease of arterial stiffness. Many authors suggest, that angiotensin converting enzyme inhibitors may exert favourable effect, irrespective of blood pressure. Arterial stiffness assessment may become a cardiovascular risk parameter and a therapeutic goal.

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Related Papers

Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension
A BenetosP Lacolley
The American Journal of Geriatric Cardiology
Rajesh V Swaminathan, Karen P Alexander
© 2022 Meta ULC. All rights reserved