PMID: 15218394Jun 26, 2004Paper

Arterial stiffness and the systolic hypertension syndrome

Current Opinion in Cardiology
Joseph L Izzo

Abstract

This review is intended to provide the background for a new comprehensive hemodynamic view of the syndrome of systolic or wide pulse pressure hypertension and its hallmark abnormality: increased central arterial stiffness. Studies of the pathogenesis of systolic hypertension have lagged. This review describes the systolic hypertension syndrome as a complex set of hemodynamic maladaptations that include stiff central arteries, normal peripheral arteries with variable pressure amplification characteristics, arteriolar constriction, microcirculatory rarefaction, metabolic abnormalities, cardiac hypertrophy, and increased blood pressure variability. Because the structural and functional properties of arteries of different caliber are highly heterogeneous and vary with aging and disease, simple measurements such as standard brachial artery blood pressure, brachial pulse pressure, or mean arterial pressure are inadequate to provide meaningful insight into the pathophysiology of the syndrome. Additional parameters developed to describe changes in arterial mechanics (arterial compliance or stiffness, elastic modulus, impedance, pulse wave velocity, augmentation index, and pulse pressure amplification) are intrinsically limited and are ...Continue Reading

References

Apr 18, 1977·JAMA : the Journal of the American Medical Association·J J BooksteinS S Franklin
Aug 1, 1992·Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension·S M Finkelstein, J N Cohn
Jan 1, 1991·Journal of Cardiovascular Pharmacology·A BenetosM Safar
Feb 1, 1989·Journal of the American College of Cardiology·R N IsnardM E Safar
May 1, 1988·The American Journal of Cardiology·R G AsmarM E Safar
Jul 1, 1986·American Heart Journal·J J Toto-MoukouoM E Safar
Sep 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·R ZatzB M Brenner
Sep 20, 1973·The American Journal of Cardiology·J Koch-Weser
Apr 1, 1971·The American Journal of Cardiology·W B KannelM J Schwartz
May 1, 1982·Journal of the American Geriatrics Society
Apr 1, 1993·Journal of Hypertension·M F O'Rourke, R P Kelly
Oct 1, 1993·Circulation·P V VaitkeviciusE G Lakatta
Nov 1, 1995·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·R S VasanD Levy
Aug 1, 1996·Kidney International·G M LondonF Metivier
Mar 6, 1998·Journal of Hypertension·M E SafarG M London
Apr 16, 1998·American Heart Journal·C PitsavosP Toutouzas
Apr 29, 1998·Arteriosclerosis, Thrombosis, and Vascular Biology·J BlacherG M London
May 11, 1999·Circulation·J BlacherG M London

❮ Previous
Next ❯

Citations

Feb 20, 2008·Aging Clinical and Experimental Research·Kevin S HeffernanBo Fernhall
Mar 23, 2005·Current Opinion in Pharmacology·Burton E Sobel, David J Schneider
Nov 18, 2010·Cardiology in the Young·André JakobBrigitte Stiller
May 2, 2009·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Youko KajiHiroshi Ito
Nov 6, 2012·European Heart Journal Cardiovascular Imaging·Rogério TeixeiraLuís Providência
Jul 18, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Li-Tao ChengTao Wang
Sep 17, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Mufaddal F KhedaWilliam D Paulson
May 26, 2006·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·G TsivgoulisM Mavrikakis
Feb 14, 2006·Annals of the Rheumatic Diseases·H K ChangM Y Rhee
Jan 31, 2009·Journal of Applied Physiology·Marisa Garcia, Ghassan S Kassab
Sep 6, 2007·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Tokihisa NagaiKatsuhiko Kohara
Jul 18, 2008·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Elizabeth S MuxfeldtGil F Salles
Aug 17, 2011·Cardiology Research and Practice·Jochen SteppanDaniel Nyhan
Nov 12, 2013·Journal of Cardiovascular Translational Research·Lawrence E GreitenVirginia M Miller
Dec 3, 2014·The Surgical Clinics of North America·R Shayn MartinMichael C Chang
Jan 3, 2006·FEBS Letters·Gaetan GavazziKarl-Heinz Krause
Oct 30, 2010·Clinical and Experimental Hypertension : CHE·Ciaran ScallanStella S Daskalopoulou
Nov 8, 2015·European Heart Journal Cardiovascular Imaging·Rogério TeixeiraLino Gonçalves
Jul 14, 2010·Journal of Cardiothoracic and Vascular Anesthesia·Raj K ModakJohn A Elefteriades
May 12, 2009·The Medical Clinics of North America·Anil Verma, Scott D Solomon
Oct 18, 2005·The Journal of Clinical Hypertension·Thomas D GilesMichael A Weber
Oct 26, 2005·The American Journal of Geriatric Cardiology·Joseph L Izzo
Aug 10, 2006·The Journal of Clinical Hypertension·Adviye ErgulL Michael Prisant
Oct 7, 2011·The Journal of Clinical Hypertension·Shailesh NandishRobert Chilton
Sep 13, 2005·Pharmacology & Therapeutics·Francisco J López-Hernández, José M López-Novoa
May 6, 2005·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Mario R García-PalmieriPaul D Sorlie
Nov 5, 2008·Journal of Atherosclerosis and Thrombosis·Kosuke SakaneKazuhide Yamamoto
May 20, 2015·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Christian OttRoland E Schmieder
Mar 5, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Yi-Ting TienPo-Lin Chen
Oct 16, 2012·Journal of the American College of Cardiology·Mathias C BrandtUta C Hoppe
Apr 2, 2011·Journal of the American College of Cardiology·João L CavalcanteMouaz H Al-Mallah
May 18, 2016·European Journal of Applied Physiology·Anders SahlénZee Pin Ding
Aug 9, 2016·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Thomas OkonPhilipp Lurz
Jul 14, 2016·American Journal of Hypertension·Benjamin Gavish, Joseph L Izzo
Jan 15, 2017·BMC Cardiovascular Disorders·Monika BiesevicieneRaimonda Verseckaite
Jan 1, 2012·JRSM Cardiovascular Disease·Ursula QuinnJohn R Cockcroft
Dec 21, 2017·Frontiers in Genetics·Laura M Senatus, Ann Marie Schmidt

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Cardiomegaly

Cardiomegaly, known as an enlarged heart, is a multifactorial disease with different pathophysiological mechanisms. Hypertension, pregnancy, exercise-induced and idiopathic causes are some mechanisms of cardiomegaly. Discover the latest research of cardiomegaly here.