PMID: 26803723Jan 25, 2016Paper

Arterial Stiffness, Distensibility, and Strain in Asthmatic Children

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Esra Akyüz ÖzkanEsra Domur

Abstract

We hypothesized that since asthma is a chronic inflammatory disease, it could lead to the early development of atherosclerosis in childhood-onset asthma. The aim of this study was to investigate arterial stiffness, distensibility, and strain of different peripheral arteries, the parameters of which can be used to detect atherosclerosis in asthmatic children. We studied 22 pediatric patients with asthma and 18 healthy children. Fasting blood glucose and cholesterol levels were evaluated to exclude children with diabetes and hyperlipidemia, which are risk factors for atherosclerosis. Renal, carotid, and brachial arteries diameters were measured. Using the measured data, stiffness, distensibility, and strain of the arteries of all children were calculated. Pulse pressure, systolic and diastolic blood pressure, heart rate, cholesterols, and glucose levels of the obese individuals were similar to the controls. In carotid arteries there were no statistical differences regarding stiffness, distensibility, and strain. According to multiple ANCOVA analysis, distensibility and strain of right and left brachial arteries and right renal artery were higher, whereas right renal artery stiffness was lower in asthmatic children than in control...Continue Reading

Citations

Jul 9, 2016·BMC Cardiovascular Disorders·Esra Akyüz Özkan, Hashem E Khosroshahi
Feb 8, 2018·European Journal of Pediatrics·Julia DratvaNicole Probst-Hensch
Dec 1, 2020·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Zeynep KarakayaMustafa Arga

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