Arterial Stiffness is an Independent Risk Factor for Anemia After Percutaneous Native Kidney Biopsy

Kidney & Blood Pressure Research
Keiko TanakaJun Wada

Abstract

Bleeding is the most common complication after renal biopsy. Although numerous predictors of bleeding have been reported, it remains unclear whether arterial stiffness affects bleeding complications. We performed an observational study of the renal biopsies performed in our division over an approximately 6-year period (May 2010 to May 2016). The clinical and laboratory factors were analyzed to reveal the risk factors associated with bleeding, with a focus on anemia (defined as a ≥10% decrease in hemoglobin [Hb] after biopsy). The brachial-ankle pulse wave velocity (baPWV) was measured to evaluate arterial stiffness. This study included 462 patients (male, n=244; female, n=218). Anemia (defined above) was observed in 54 patients (11.7%). The risk of anemia was higher in women, older patients, and patients with lower serum albumin, lower eGFR and lower diastolic blood pressure after biopsy. We then performed a further analysis of 187 patients whose baPWV data were available. Multivariate analysis revealed that a higher baPWV was an independent risk factor for anemia. ROC analysis for predicting anemia found that a baPWV value of 1839 cm/s had the best performance (AUC 0.689). An increased baPWV may be a more valuable predictor of...Continue Reading

Citations

Nov 12, 2017·CEN Case Reports·Yoichi TakeuchiTasuku Nagasawa
Jan 27, 2021·Acta Radiologica·Dharmendra BhadauriaNarayan Prasad
Oct 17, 2020·Clinical Journal of the American Society of Nephrology : CJASN·Emilio D PoggioUNKNOWN Kidney Precision Medicine Project
Feb 20, 2021·Clinical and Experimental Nephrology·Yoshifumi UbaraUNKNOWN Committee of Practical Guide for Kidney Biopsy 2020
May 1, 2021·Healthcare·Kenta TorigoeTomoya Nishino

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