Arteriovenous glomeruli of the human spinal cord and their possible functional implications

Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists
Wesley W Parke

Abstract

A previous investigation of the radiculomedullary vascular distribution of the human spinal cord showed an immediate filling of the peripheral spinal veins during arterial injections. Because the perfused medium, a mixture of latex and India ink, had a sufficient viscosity to preclude capillary passage, an extensive system of arteriovenous anastomoses (AVA) was indicated. The injection of five additional anatomic cadaver spinal cords was undertaken to specifically determine the intraparenchymal position and structure of these AVA. It was found that only cleared and transilluminated longitudinal parasagittal sections adequately showed that the AVA were formed by an extensive array of intricately coiled arteriovenous glomeruli (AVG) that could pass substantial amounts of blood from third order arterial branches to equivalently sized veins, bypassing the capillary bed. The epithelioid structure of these AVG channel walls, coupled with their highly innervated adventitial tissue indicated a possible functional relationship to similar structures found in the ends (digital pads) of mammalian extremities. Stained serial sections of injected cords showed the vascular relations with nerve fibers derived from the intraspinal parenchyma as...Continue Reading

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Citations

Jun 15, 2011·Journal of Neurosurgery. Spine·Nikolay L MartirosyanMark C Preul
Nov 16, 2013·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Marc SoubeyrandJacques Duranteau
Feb 26, 2014·Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·Kati HaenssgenValentin Djonov
Apr 7, 2007·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·K JellemaJ van Gijn

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