Arthrofibrosis and large joint scarring

Connective Tissue Research
Antonia F ChenJoseph A Abboud

Abstract

Large joint arthrofibrosis and scarring, involving the shoulder, elbow, hip, and knee, can result in the loss of function and immobility. The pathway of joint contracture formation is still being elucidated and is due to aberrations in collagen synthesis and misorientation of collagen fibrils. Novel antibodies are being developed to prevent arthrofibrosis, and current treatment methods for arthrofibrosis include medical, physical, and surgical treatments. This article describes the biology of joint contracture formation, along with current and future pharmacologic, biologic, and medical interventions.

References

Jun 1, 1984·Annals of the Rheumatic Diseases·D Y BulgenS Roberts
Jan 1, 1995·Annual Review of Biochemistry·D J Prockop, K I Kivirikko
Dec 1, 1996·Acta Orthopaedica Scandinavica·J O Søjbjerg
Dec 22, 1999·Seminars in Cell & Developmental Biology·S R Lamandé, J F Bateman
Mar 4, 2000·The Journal of Bone and Joint Surgery. British Volume·J J GelinasG J King
Mar 16, 2000·Journal of Shoulder and Elbow Surgery·R M DodenhoffS A Copeland
Jul 30, 2002·Hand Clinics·Dimitris G VardakasDean G Sotereanos
Dec 7, 2002·Journal of Shoulder and Elbow Surgery·Craig M BallKen Yamaguchi
May 6, 2003·The Journal of Bone and Joint Surgery. British Volume·H B HindmanM Spector
Jan 1, 1965·Acta Orthopaedica Scandinavica·L ANDREN, B J LUNDBERG
Mar 5, 2004·Journal of Shoulder and Elbow Surgery·Bart M BerghsTimothy D Bunker
Mar 17, 2004·Clinical Orthopaedics and Related Research·Kevin A HildebrandDavid A Hart
May 27, 2004·The Journal of the American Academy of Orthopaedic Surgeons·Matthew R Bong, Paul E Di Cesare
Jul 27, 2004·British Journal of Sports Medicine·R Buchbinder, S Green
Feb 22, 2005·Journal of Shoulder and Elbow Surgery·Markus LoewBurkhard Lehner
Oct 1, 2005·Journal of Shoulder and Elbow Surgery·Christopher M FarrellRobert H Cofield
Oct 6, 2005·Clinical Orthopaedics and Related Research·Kevin A HildebrandDavid A Hart
Apr 8, 2006·Clinical Orthopaedics and Related Research·Alejandro N BugnoneScott Humble
Oct 13, 2006·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·M H BaumsH-M Klinger
Jan 2, 2007·Clinical Orthopaedics and Related Research·Kevin A HildebrandDavid A Hart
Mar 21, 2007·Journal of Shoulder and Elbow Surgery·Mark S CohenCarol Muehleman
Jun 23, 2007·Journal of Pediatric Orthopedics·Wesley P BevanKit Song
Sep 1, 2007·Toxicologic Pathology·Hamid Namazi, Simin Torabi
Oct 2, 2007·The Journal of Bone and Joint Surgery. British Volume·N A QuraishiA J Chakrabarti
May 27, 2009·Current Reviews in Musculoskeletal Medicine·Robert C Manske, Daniel Prohaska
May 28, 2009·Archives of Orthopaedic and Trauma Surgery·Murat CinarMustafa Uysal
Jul 8, 2009·Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology·Alfredo Schiavone PanniMario Tartarone
Oct 15, 2009·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Peter M BonuttiMichael G Zywiel
Oct 20, 2009·Journal of Shoulder and Elbow Surgery·Arash AraghiBernard Morrey
Jan 21, 2010·Clinical Orthopaedics and Related Research·Sean E FitzsimmonsMichael J Bronson
Jul 6, 2010·Aesthetic Surgery Journal·Catherine K Huang, Neal Handel
Dec 21, 2010·Journal of Shoulder and Elbow Surgery·Jason E HsuJoseph A Abboud
Sep 23, 2011·The Journal of Bone and Joint Surgery. American Volume·Michael J GriesserGrant L Jones
Nov 8, 2011·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Matthew P AbdelJoaquin Sanchez-Sotelo
Dec 17, 2011·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Michael J MonumentKevin A Hildebrand
Jan 6, 2012·The Journal of Bone and Joint Surgery. British Volume·C M RobinsonI R Murray
Apr 21, 2012·The Journal of Bone and Joint Surgery. American Volume·Anneluuk L C LindenhoviusDavid Ring

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA
E Eriksson
Instructional Course Lectures
T N LindenfeldA Husain
Der Orthopäde
Ulrich Bosch
Seminars in Musculoskeletal Radiology
James M Linklater, Chris K Fessa
© 2022 Meta ULC. All rights reserved