Arthropathy associated with Brucella abortus strain 19 vaccination in cattle. I. Examination of field cases

The British Veterinary Journal
M J CorbelR Bradley

Abstract

Thirty cows presenting with lameness and persistent serological reactions to Brucella abortus had chronic granulomatous arthropathy of the femorotibial and occasionally other joints. Attempts to culture Brucella or other pathogens gave negative results but organisms of Brucella morphology were seen in fluorescent antibody-stained cryostat sections of synovial tissue. The synovial fluids contained high titres of antibodies to B. abortus and Yersinia enterocolitica O:9 and had elevated total protein and immunoglobulin concentrations showing an oligoclonal electrophoretic profile. Immune complexes and rheumatoid factor were detected in some of the fluids.

Citations

Nov 5, 2002·Veterinary Microbiology·Gerhardt G SchurigMichael J Corbel
Dec 26, 2009·Journal of Comparative Pathology·A M DanscherO L Nielsen
Jan 1, 1994·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·B JohnsonA W Confer
Feb 13, 2021·Pathogens·Gabriela González-EspinozaJean-Pierre Gorvel

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