Articaine infiltration for anesthesia of mandibular first molars

Journal of Endodontics
I P CorbettJ G Meechan

Abstract

A randomized, controlled trial of 31 healthy volunteers compared 4% articaine with 1:100,000 epinephrine buccal infiltration to buccal plus lingual infiltration of the same dose of drug in achieving pulpal anesthesia of mandibular first molar teeth. Data were compared with efficacy of an inferior alveolar nerve block using 2% lidocaine 1:80,000 epinephrine in a cohort of 27 of the volunteers. Anesthesia was determined using electronic pulp testing. Buccal and buccal plus lingual infiltrations of articaine with epinephrine did not differ in efficacy in obtaining pulpal anesthesia for mandibular permanent first molars (p = 0.17). Efficacy of 4% articaine with epinephrine infiltrations for first molar pulp anesthesia was similar to that of an IANB using lidocaine with epinephrine over a 30-minute study period (96 and 80 episodes of no response to maximal stimulation respectively, p = 0.097). Subjective tooth numbness was more common after IANB than buccal infiltration (p = 0.005). The discomfort of buccal infiltration with articaine was volume dependent (p = 0.017) and similar to that of an IANB.

References

Dec 1, 1992·Journal of Dentistry·J G Meechan
Jan 1, 1997·Pediatric Cardiology·G J RobertsP Longhurst
Sep 19, 1997·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·M A PogrelR Ahani
Jan 22, 1998·Clinical Pharmacokinetics·R OertelW Kirch
Jun 1, 2000·The Journal of the American Dental Association·S F MalamedD Leblanc
Feb 24, 2001·The Journal of the American Dental Association·S F MalamedD Leblanc
Aug 16, 2001·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·T YonchakW J Meyers
Jul 27, 2002·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Leena YlikontiolaKyösti Oikarinen
Nov 28, 2002·International Endodontic Journal·J G Meechan
Mar 29, 2005·Journal of Endodontics·Philip MikesellJoel Weaver
Oct 24, 2006·Journal of Endodontics·Jason BigbyJoel Weaver
Nov 4, 2006·The Journal of the American Dental Association·Elliot V HershRaymond R Townsend
Dec 2, 2006·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Sina UckanKenan Araz
Dec 21, 2006·Anesthesia Progress·Amanda GoodmanJoel Weaver
May 2, 2007·Journal of Periodontology·Amar KatranjiHom-Lay Wang
Aug 3, 2007·The Journal of the American Dental Association·Douglas RobertsonMelissa McCartney

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Citations

Dec 14, 2012·European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry·R LeithA C O'Connell
Jul 25, 2009·European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry·J G Meechan
Sep 18, 2013·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Khalid E El-Kholey
Sep 14, 2010·Dental Clinics of North America·John G Meechan
Mar 12, 2010·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Masoud ParirokhPaul V Abbott
Aug 5, 2010·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·J G Meechan
Dec 23, 2008·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Narasimhan SrinivasanGovindasamy Padmini
Jan 27, 2009·Journal of Endodontics·Isabel Peixoto TortamanoPaschoal Laércio Armonia
Dec 25, 2009·Clinical Implant Dentistry and Related Research·Norbert EnklingKarl-Heinz Utz
Jan 12, 2010·International Journal of Paediatric Dentistry·Ghaeth H Yassen
May 3, 2011·The Journal of the American Dental Association·Ryan G BrandtMathilde C Peters
Sep 9, 2011·The Journal of the American Dental Association·John G Meechan
Jul 30, 2016·The Journal of Clinical Pediatric Dentistry·Ülkü Şermet ElbayÜlkem Cilasun
Nov 1, 2013·Brazilian Dental Journal·Isabel Peixoto TortamanoRodney Garcia Rocha
Apr 9, 2011·British Dental Journal·K E YappP Parashos
Mar 1, 2019·Haemophilia : the Official Journal of the World Federation of Hemophilia·Alison DougallBlanaid Daly

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