PMID: 16511790Mar 3, 2006Paper

Artifactual changes in canine blood following storage, detected using the ADVIA 120 hematology analyzer

Veterinary Clinical Pathology
Tommaso FurlanelloLaia Solano-Gallego

Abstract

Artifactual changes in blood may occur as a consequence of delayed analysis and may complicate interpretation of CBC data. The aim of this study was to characterize artifactual changes in canine blood, due to storage, using the ADVIA 120 hematology analyzer. Blood samples were collected into EDTA from 5 clinically healthy dogs. Within 1 hour after blood sample collection and at 12, 24, 36 and 48 hours after storage of the samples at either 4 degrees C or room temperature (approximately 24 degrees C), a CBC was done using the ADVIA 120 and multispecies software. A linear mixed model was used to statistically evaluate significant differences in values over time, compared with initial values. The HCT and MCV were increased significantly after 12 hours of collection at both 4 degrees C and 24 degrees C, and continued to increase through 48 hours. The MCHC initially decreased significantly at 12-24 hours and then continued to decrease through 48 hours at both temperatures. Changes in HCT, MCV, and MCHC were greater at 24 degrees C than at 4 degrees C at all time points. A significant increase in MPV and a decrease in mean platelet component concentration were observed at all time points at 24 degrees C. Samples stored at 24 degrees ...Continue Reading

Citations

Mar 28, 2008·Veterinary Clinical Pathology·Alessia GiordanoSaverio Paltrinieri
Oct 2, 2009·Veterinary Clinical Pathology·Lise NielsenAnnemarie T Kristensen
Feb 14, 2012·Veterinary Clinical Pathology·Natali B BauerAndreas Moritz
Aug 14, 2009·Journal of Avian Medicine and Surgery·Renata Padrtova, Christopher G Lloyd
Oct 23, 2010·Research in Veterinary Science·B FlatlandB W Rohrbach
Jul 3, 2007·Research in Veterinary Science·Mark GoodfellowEdward Hall
Mar 6, 2007·The Veterinary Clinics of North America. Small Animal Practice·James H Meinkoth, Robin W Allison
May 7, 2014·Veterinary Clinical Pathology·R LavouéC Trumel
Jul 24, 2014·Veterinary Clinical Pathology·Ahmira R TorresRichard C Hill
Jul 30, 2014·Veterinary Clinical Pathology·Alejandro Perez-EcijaFrancisco J Mendoza
Dec 24, 2014·American Journal of Veterinary Research·Jennifer M ReinhartThomas Schermerhorn
May 9, 2014·Veterinary Pathology·C N Grimes, M M Fry
Jan 19, 2017·Journal of Veterinary Emergency and Critical Care·Kate S FarrellLauren A Sullivan
Mar 1, 2012·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Natali BauerAndreas Moritz
Mar 1, 2012·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Natali BauerAndreas Moritz
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Mar 5, 2008·Journal of the American Animal Hospital Association·Tamara B Wills, K Jane Wardrop
Jun 27, 2019·Veterinary Clinical Pathology·Liza Bau-Gaudreault, Carolyn N Grimes
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Dec 15, 2020·Veterinary Clinical Pathology·Bente Flatland, Kathleen P Freeman
Jun 22, 2021·Veterinary Clinical Pathology·Margot GrebertCatherine Trumel
May 10, 2020·Acta Veterinaria Hungarica·Paola ScarpaSaverio Paltrinieri

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