Artificial intelligence and algorithmic computational pathology: an introduction with renal allograft examples.

Histopathology
Alton B FarrisJulien Hogan

Abstract

Whole slide imaging, which is an important technique in the field of digital pathology, has recently been the subject of increased interest and avenues for utilisation, and with more widespread whole slide image (WSI) utilisation, there will also be increased interest in and implementation of image analysis (IA) techniques. IA includes artificial intelligence (AI) and targeted or hypothesis-driven algorithms. In the overall pathology field, the number of citations related to these topics has increased in recent years. Renal pathology is one anatomical pathology subspecialty that has utilised WSIs and IA algorithms; it can be argued that renal transplant pathology could be particularly suited for whole slide imaging and IA, as renal transplant pathology is frequently classified by use of the semiquantitative Banff classification of renal allograft pathology. Hypothesis-driven/targeted algorithms have been used in the past for the assessment of a variety of features in the kidney (e.g. interstitial fibrosis, tubular atrophy, inflammation); in recent years, the amount of research has particularly increased in the area of AI/machine learning for the identification of glomeruli, for histological segmentation, and for other applicati...Continue Reading

References

Jan 12, 1989·Nature·F Crick
Jan 23, 1999·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·C K AbrassC L Davis
Nov 24, 1999·Pediatric Transplantation·P C GrimmD N Rush
Jan 6, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·E De HeerL A van Es
May 23, 2003·Journal of the American Society of Nephrology : JASN·Paul C GrimmDavid N Rush
Feb 21, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Montserrat M Diaz EncarnacionJoseph P Grande
Sep 24, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ståle SundTorstein Hovig
Oct 22, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A ServaisE Thervet
Dec 1, 2010·Journal of the American Society of Nephrology : JASN·Alton B FarrisRobert B Colvin
Jun 16, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A ServaisE Thervet
Nov 8, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·K IsseA J Demetris
Aug 9, 2012·Development·Adrienne H K RoederElliot M Meyerowitz
Sep 7, 2012·BMC Medicine·James SoraceW Dean Wallace
Feb 2, 2013·Journal of Pathology Informatics·Liron PantanowitzAnil V Parwani
Jul 31, 2013·Journal of the American Medical Informatics Association : JAMIA·David A GutmanLee A D Cooper
Apr 10, 2014·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A B FarrisM Mengel
Jun 23, 2015·Archives of Pathology & Laboratory Medicine·David N LouisMichael J Becich
Aug 26, 2015·Journal of the American Society of Nephrology : JASN·Richard TorresRobert Safirstein
Oct 2, 2015·BMC Bioinformatics·Tsuyoshi KatoKinya Okada
Nov 18, 2015·Circulation·Rahul C Deo
Dec 20, 2015·Journal of the American Society of Nephrology : JASN·Vincent VuibletPhilippe Rieu
Sep 30, 2016·The New England Journal of Medicine·Ziad Obermeyer, Ezekiel J Emanuel
Feb 6, 2017·Archives of Pathology & Laboratory Medicine·Alton Brad FarrisGeoffrey H Smith
Oct 3, 2017·Journal of Pathology Informatics·Navid FarahaniLiron Pantanowitz
Nov 8, 2017·Scientific Reports·Michael NalisnikLee A D Cooper
Nov 9, 2017·Virchows Archiv : an International Journal of Pathology·Andres MoonAlton B Brad Farris
Dec 14, 2017·JAMA : the Journal of the American Medical Association·Babak Ehteshami BejnordiRui Venâncio
Dec 16, 2017·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M HaasM Mengel
Mar 14, 2018·Proceedings of the National Academy of Sciences of the United States of America·Pooya MobadersanyLee A D Cooper
May 5, 2018·KI Reports·Vijaya B KolachalamaVipul C Chitalia

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.