Artificial intelligence as the next step towards precision pathology.

Journal of Internal Medicine
B AcsJohan Hartman

Abstract

Pathology is the cornerstone of cancer care. The need for accuracy in histopathologic diagnosis of cancer is increasing as personalized cancer therapy requires accurate biomarker assessment. The appearance of digital image analysis holds promise to improve both the volume and precision of histomorphological evaluation. Recently, machine learning, and particularly deep learning, has enabled rapid advances in computational pathology. The integration of machine learning into routine care will be a milestone for the healthcare sector in the next decade, and histopathology is right at the centre of this revolution. Examples of potential high-value machine learning applications include both model-based assessment of routine diagnostic features in pathology, and the ability to extract and identify novel features that provide insights into a disease. Recent groundbreaking results have demonstrated that applications of machine learning methods in pathology significantly improves metastases detection in lymph nodes, Ki67 scoring in breast cancer, Gleason grading in prostate cancer and tumour-infiltrating lymphocyte (TIL) scoring in melanoma. Furthermore, deep learning models have also been demonstrated to be able to predict status of som...Continue Reading

References

May 1, 1996·Computers in Biology and Medicine·S H OngR Sinniah
Jul 27, 2000·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·L W DaltonR W Blamey
Nov 2, 2006·Genome Biology·Anne E CarpenterDavid M Sabatini
Apr 3, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sherene LoiChristos Sotiriou
May 6, 2008·The Breast : Official Journal of the European Society of Mastology·R Stuart-HarrisP Pharoah
Apr 22, 2009·Expert Review of Molecular Diagnostics·Dimitrios H Roukos
Jun 3, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Mary L Disis
Jan 1, 2009·IEEE Reviews in Biomedical Engineering·Metin N GurcanB Yener
Feb 3, 2011·Archives of Pathology & Laboratory Medicine·Marios A GavrielidesStephen M Hewitt
Apr 13, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sahar M A MahmoudAndrew R Green
Apr 23, 2011·Breast Cancer Research and Treatment·Anja BrügmannMogens Vyberg
Oct 1, 2011·Journal of the National Cancer Institute·Mitch DowsettUNKNOWN International Ki-67 in Breast Cancer Working Group
Mar 16, 2012·Nature Reviews. Cancer·Wolf Herman FridmanJérôme Galon
Apr 14, 2012·IEEE Transactions on Medical Imaging·Sahirzeeshan Ali, Anant Madabhushi
Aug 30, 2012·Nature Methods·Caroline A SchneiderKevin W Eliceiri
Nov 24, 2012·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Patricia S NielsenTorben Steiniche
Dec 18, 2012·Histopathology·Lars EgevadPhilippe Camparo
Sep 21, 2013·Nature Immunology·Thomas F GajewskiYang-Xin Fu
Nov 6, 2013·Laboratory Investigation; a Journal of Technical Methods and Pathology·Jason R BrownDavid L Rimm
Nov 10, 2013·Journal of the National Cancer Institute·Mei-Yin C PolleyUNKNOWN International Ki67 in Breast Cancer Working Group of the Breast International Group and North American Breast Cancer Group
Dec 10, 2013·The Breast : Official Journal of the European Society of Mastology·Carmen CriscitielloGiuseppe Curigliano
Jan 25, 2014·Nature Reviews. Cancer·Pierre G CoulieThierry Boon
Apr 25, 2014·IEEE Transactions on Bio-medical Engineering·Mitko VetaMax A Viergever
May 23, 2014·IEEE Transactions on Bio-medical Engineering·Adnan Mujahid KhanDerek Magee
Dec 17, 2014·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Frederick KlauschenGunter von Minckwitz
May 6, 2015·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A S CoatesUNKNOWN Panel Members
May 29, 2015·Nature·Yann LeCunGeoffrey Hinton
Jun 26, 2015·Breast Cancer Research and Treatment·Henrik Holten-RossingBen Vainer
Jul 15, 2015·European Urology·Jonathan I EpsteinEric A Klein
Aug 19, 2015·Journal of Clinical Pathology·Kelly ElliottPerry Maxwell
Jan 16, 2016·Histopathology·Zuzana Kos, David J Dabbs
Feb 3, 2016·Cancer Cytopathology·Perry Maxwell, Manuel Salto-Tellez
Feb 27, 2016·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Gustav StålhammarJohan Hartman
Nov 3, 2016·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Barbara Ingold HeppnerSibylle Loibl
May 24, 2016·Scientific Reports·Geert LitjensJeroen van der Laak
Jul 2, 2016·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Carsten DenkertRoberto Salgado
Aug 27, 2016·Journal of Pathology Informatics·Andrew Janowczyk, Anant Madabhushi
Dec 8, 2016·The Lancet Oncology·Geoffrey T GibneyMichael B Atkins
Jan 28, 2017·Metabolism: Clinical and Experimental·Pavel Hamet, Johanne Tremblay

❮ Previous
Next ❯

Citations

Jul 21, 2020·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Stefan W Krause
Sep 4, 2020·Current Opinion in Urology·Victor M SchuettfortShahrokh F Shariat
Sep 18, 2020·Clinical Journal of the American Society of Nephrology : CJASN·Jean Hou, Cynthia C Nast
Jun 23, 2020·Journal of the Chinese Medical Association : JCMA·Ying-Chun JhengDe-Kuang Hwang
Oct 1, 2020·Computational and Structural Biotechnology Journal·Erik Meijering
Dec 12, 2020·Computers in Biology and Medicine·Fei DengLanjing Zhang
Feb 2, 2021·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Yuanchuan ZhangZiqiang Wang
Jan 17, 2021·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Yunjie HeStephen T C Wong
Jan 13, 2021·Cancer Immunology Research·Xiaoli LiuZhiyun Yang
Apr 4, 2021·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Sabine OskarMary Beth Terry
Mar 31, 2021·Current Opinion in Oncology·Marion ClasseEric Deutsch
May 21, 2021·Journal of Pathology Informatics·André HomeyerPeter Hufnagl
Feb 12, 2021·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Amaro Taylor-WeinerZobair M Younossi
Jul 1, 2021·Scientific Reports·Luís A Vale-Silva, Karl Rohr
Jul 15, 2021·Scientific Reports·Sara P OliveiraJaime S Cardoso
Jul 25, 2021·Medical & Biological Engineering & Computing·M A Aswathy, M Jagannath
Aug 20, 2021·Gene·Deepti MalikBikash Medhi
Aug 28, 2021·International Journal of Molecular Sciences·Nicole BussolaGiuseppe Jurman
Jul 25, 2021·British Journal of Pharmacology·Christophe KleinMaria Chiara Maiuri
Jan 26, 2021·Archives of Pathology & Laboratory Medicine·James H HarrisonMichelle N Stram

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Cancer: Therapeutic Approaches

Several different therapeutic approaches are used to treat breast cancer. These include chemotherapy, hormonal therapy, targeted therapy, and Immunotherapy. Discover the latest research on breast cancer therapeutic approaches here.

Related Papers

Translational Research : the Journal of Laboratory and Clinical Medicine
Stephanie RobertsonJohan Hartman
Advances in Experimental Medicine and Biology
Eugene Lin, Shih-Jen Tsai
The Journal of Dermatological Treatment
Shannon WongvibulsinShawn G Kwatra
© 2021 Meta ULC. All rights reserved