Artificial intelligence for detecting mitral regurgitation using electrocardiography.

Journal of Electrocardiology
Joon-Myoung KwonByung-Hee Oh

Abstract

Screening and early diagnosis of mitral regurgitation (MR) are crucial for preventing irreversible progression of MR. In this study, we developed and validated an artificial intelligence (AI) algorithm for detecting MR using electrocardiography (ECG). This retrospective cohort study included data from two hospital. An AI algorithm was trained using 56,670 ECGs from 24,202 patients. Internal validation of the algorithm was performed with 3174 ECGs of 3174 patients from one hospital, while external validation was performed with 10,865 ECGs of 10,865 patients from another hospital. The endpoint was the diagnosis of significant MR, moderate to severe, confirmed by echocardiography. We used 500 Hz ECG raw data as predictive variables. Additionally, we showed regions of ECG that have the most significant impact on the decision-making of the AI algorithm using a sensitivity map. During the internal and external validation, the area under the receiver operating characteristic curve of the AI algorithm using a 12-lead ECG for detecting MR was 0.816 and 0.877, respectively, while that using a single-lead ECG was 0.758 and 0.850, respectively. In the 3157 non-MR individuals, those patients that the AI defined as high risk had a significan...Continue Reading

Citations

Dec 4, 2020·International Journal of Cardiology·Yong-Yeon JoByung-Hee Oh
Dec 18, 2020·The Lancet. Digital Health·Joon-Myoung KwonByung-Hee Oh
Apr 23, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Songren ShuJiangping Song
Sep 18, 2021·European Heart Journal·Zachi I AttiaPaul A Friedman
Oct 5, 2021·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Joon-Myoung KwonKyung-Hee Kim
Apr 13, 2021·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Wen-Cheng LiuChin Lin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Joon-Myoung KwonByung-Hee Oh
Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Emma SvennbergMårten Rosenqvist
Vojnosanitetski pregled. Military-medical and pharmaceutical review
Aleksandra GrdinićRadomir Matunović
Journal of Electrocardiology
Richard E GreggSaeed Babaeizadeh
© 2021 Meta ULC. All rights reserved