Artificial intelligence in oncology

Cancer Science
Hideyuki Shimizu, Keiichi I Nakayama

Abstract

Artificial intelligence (AI) has contributed substantially to the resolution of a variety of biomedical problems, including cancer, over the past decade. Deep learning, a subfield of AI that is highly flexible and supports automatic feature extraction, is increasingly being applied in various areas of both basic and clinical cancer research. In this review, we describe numerous recent examples of the application of AI in oncology, including cases in which deep learning has efficiently solved problems that were previously thought to be unsolvable, and we address obstacles that must be overcome before such application can become more widespread. We also highlight resources and datasets that can help harness the power of AI for cancer research. The development of innovative approaches to and applications of AI will yield important insights in oncology in the coming decade.

References

Mar 23, 2013·Cancer Cell·Shoichiro TakeishiKeiichi I Nakayama
May 29, 2015·Nature·Yann LeCunGeoffrey Hinton
Jul 8, 2015·PLoS Biology·Zachary D StephensGene E Robinson
Oct 7, 2015·IEEE Transactions on Medical Imaging·Holger RothRonald Summers
Apr 27, 2016·Cancer Science·Shoichiro Takeishi, Keiichi I Nakayama
May 24, 2016·Scientific Reports·Geert LitjensJeroen van der Laak
Jul 31, 2016·Molecular Systems Biology·Christof AngermuellerOliver Stegle
Sep 8, 2016·Nature Medicine·Stanley Chun-Wei Lee, Omar Abdel-Wahab
Sep 17, 2016·Nature Communications·Scott HorowitzJames C A Bardwell
Nov 30, 2016·JAMA : the Journal of the American Medical Association·Varun GulshanDale R Webster
Dec 3, 2016·Nucleic Acids Research·Simon A ForbesPeter J Campbell
Dec 28, 2016·IEEE Transactions on Medical Imaging·Lequan YuPheng-Ann Heng
Feb 6, 2017·Current Opinion in Genetics & Development·Derick C HoskinsonHeather Mason-Suares
Feb 9, 2017·Medical Image Analysis·Neeraj DhungelAndrew P Bradley
Mar 17, 2017·Annual Review of Biomedical Engineering·Dinggang ShenHeung-Il Suk
Apr 6, 2017·Scientific Reports·Michel E VandenbergheCraig Barker
May 10, 2017·Briefings in Bioinformatics·Riccardo MiottoJoel T Dudley
Aug 5, 2017·Medical Image Analysis·Geert LitjensClara I Sánchez
Sep 9, 2017·Seminars in Cancer Biology·Andrea NicoliniMichael J Duffy
Nov 10, 2017·Trends in Cancer·Syn Kok Yeo, Jun-Lin Guan
Nov 22, 2017·The Oncologist·Nirali M PatelWilliam Y Kim
Dec 1, 2017·MHealth·Bertalan MeskóZsuzsanna Győrffy
Dec 14, 2017·JAMA : the Journal of the American Medical Association·Babak Ehteshami BejnordiRui Venâncio
Jan 26, 2018·Drug Discovery Today·Hongming ChenThomas Blaschke
Apr 6, 2018·Journal of the Royal Society, Interface·Travers ChingCasey S Greene
May 8, 2018·Proceedings of the National Academy of Sciences of the United States of America·Ryan J DavisBruce E Clurman
Jul 1, 2018·Nature Communications·Joo Sang LeeEytan Ruppin
Aug 24, 2018·IEEE Transactions on Visualization and Computer Graphics·Daniel HaehnHanspeter Pfister
Oct 3, 2018·Computational and Structural Biotechnology Journal·Daisuke Komura, Shumpei Ishikawa
Dec 7, 2018·Japanese Journal of Radiology·Daiju UedaYukio Miki
Jan 3, 2019·Journal of Pathology and Translational Medicine·Hye Yoon ChangTae-Yeong Kwak
Jan 9, 2019·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal
Jan 22, 2019·Cell·Kishore JaganathanKyle Kai-How Farh
Mar 5, 2019·JCI Insight·Hideyuki ShimizuKeiichi I Nakayama
Mar 6, 2019·Journal of the National Cancer Institute·Alejandro Rodriguez-RuizIoannis Sechopoulos
Apr 4, 2019·The New England Journal of Medicine·Alvin RajkomarIsaac Kohane
Apr 17, 2019·JCO Clinical Cancer Informatics·Andrew JanowczykAnant Madabhushi
May 3, 2019·The Lancet Oncology·Muhammad Khalid Khan NiaziMetin N Gurcan

❮ Previous
Next ❯

Citations

Aug 18, 2020·Journal of Pharmacokinetics and Pharmacodynamics·Sara K Quinney, Peter L Bonate
Nov 4, 2020·Journal of Korean Medical Science·Chan Woo ParkHyung Jin Yoon
May 21, 2021·Skeletal Radiology·Matthew D LiConnie Y Chang
May 1, 2021·Current Opinion in Urology·Ahmad ChaddadLama Hassan
Jul 3, 2021·Expert Review of Anticancer Therapy·Gianluca FranceschiniRiccardo Masetti
Aug 11, 2021·European Journal of Nuclear Medicine and Molecular Imaging·V RomeoK Pinker
Aug 12, 2021·Nature Communications·Jay T LennonJochen Blath
Aug 12, 2021·Computational and Structural Biotechnology Journal·Raihan RafiqueJulhash U Kazi
Aug 30, 2021·International Journal of Medical Informatics·John AdeoyePeter Thomson

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Software Mentioned

DeepFocus
Proscia
Kaggle
HistoQC
Arterys
DeepVariant
PAIGE
capsuleNet
ExPecto
COSMIC

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.