Artificial intelligence mobile health platform for early detection of COVID-19 in quarantine subjects using a wearable biosensor: protocol for a randomised controlled trial

BMJ Open
Chun Ka WongIvan Fan Ngai Hung

Abstract

There is an outbreak of COVID-19 worldwide. As there is no effective therapy or vaccine yet, rigorous implementation of traditional public health measures such as isolation and quarantine remains the most effective tool to control the outbreak. When an asymptomatic individual with COVID-19 exposure is being quarantined, it is necessary to perform temperature and symptom surveillance. As such surveillance is intermittent in nature and highly dependent on self-discipline, it has limited effectiveness. Advances in biosensor technologies made it possible to continuously monitor physiological parameters using wearable biosensors with a variety of form factors. To explore the potential of using wearable biosensors to continuously monitor multidimensional physiological parameters for early detection of COVID-19 clinical progression. This randomised controlled open-labelled trial will involve 200-1000 asymptomatic subjects with close COVID-19 contact under mandatory quarantine at designated facilities in Hong Kong. Subjects will be randomised to receive a remote monitoring strategy (intervention group) or standard strategy (control group) in a 1:1 ratio during the 14 day-quarantine period. In addition to fever and symptom surveillance ...Continue Reading

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Citations

Jan 12, 2021·Journal of Medical Systems·Mostafa Al-Emran, Jesse M Ehrenfeld
Nov 19, 2020·Micromachines·Saghi Forouhi, Ebrahim Ghafar-Zadeh
Mar 19, 2021·Transplant International : Official Journal of the European Society for Organ Transplantation·Brendan J KeatingMichael P Snyder
Jun 1, 2021·Frontiers in Medicine·Anat Reiner BenaimJoachim A Behar
Jun 7, 2021·Journal of Translational Medicine·Dominik HartlAdrian Roth
Oct 7, 2021·JMIR Public Health and Surveillance·Kelly Jean Thomas CraigGretchen Purcell Jackson

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Methods Mentioned

BETA
biosensors
biosensor

Clinical Trials Mentioned

NCT04343794

Software Mentioned

Biovitals Sentinel
Biovitals Analytics Engine
Biovitals
Biovitals Analytics

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