PMID: 616275Aug 1, 1977Paper

Artificial liver: the effect of ACAC microencapsulated charcoal hemoperfusion on fulminant hepatic failure

Artificial Organs
E ChiritoT M Chang

Abstract

Control trials and statistical analysis were carried out to assess the effects of albumin-collodion microencapsulated activated charcoal (ACAC) hemoperfusion on fulminant hepatic coma. A rat model of galactosamine induced fulminant hepatic coma was used. Rats which did not recover died at 3.0+/-0.6 days after galactosamine injection. Those which survived this period recovered. Forty-eight hours after galactosamine injection, a test group of 21 rats were treated with 1 hour hemoperfusion and compared with an untreated group of 23 rats. 71.4% of the treated group survived as compared to 30.4% of the untreated rats. Statistical analysis (t test) shows a significant increase in recovery for the treated group (less than 0.01). Biochemical and histological results will be discussed.

References

Jan 4, 1975·British Medical Journal·J A ValeR Goulding
Jan 1, 1972·Transactions - American Society for Artificial Internal Organs·J D AndradeW J Kolff
Jan 1, 1974·Reviews of Physiology, Biochemistry and Pharmacology·K Decker, D Keppler
Jan 1, 1972·Transactions - American Society for Artificial Internal Organs·T M ChangT Lee-Burns
Oct 1, 1968·Experimental and Molecular Pathology·D KepplerK Decker
Mar 1, 1971·Hoppe-Seyler's Zeitschrift für physiologische Chemie·K DeckerW Domschke
Dec 1, 1969·Canadian Journal of Physiology and Pharmacology·T M Chang
Jan 1, 1966·Canadian Journal of Physiology and Pharmacology·T M ChangS G Mason
Oct 23, 1964·Science·T M CHANG
Jan 1, 1965·Transactions - American Society for Artificial Internal Organs·G DUNEA, W J KOLFF

❮ Previous
Next ❯

Citations

Nov 15, 1978·Experientia·U B Gröflin, H Thölen
Sep 1, 1983·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R A ChamuleauH W De Koning
Feb 17, 2000·Artificial Cells, Blood Substitutes, and Immobilization Biotechnology·T Chandy, G H Rao
Nov 1, 1978·Artificial Organs·J F WinchesterG E Schreiner
Oct 20, 1998·Journal of Biomaterials Applications·T Chandy, C P Sharma
Feb 3, 2016·Artificial Cells, Nanomedicine, and Biotechnology·Jian ChenYaoting Yu
Jul 1, 1988·Journal of Biomaterials Applications·T M Chang
Sep 11, 1999·Journal of Gastroenterology and Hepatology·S M Riordan, R Williams
May 1, 1979·Artificial Organs·K D Kulbe
Jan 1, 1984·Applied Biochemistry and Biotechnology·T M Chang
Jan 1, 1996·Scandinavian Journal of Gastroenterology. Supplement·V Dixit, G Gitnick
Jan 1, 1987·Biomaterials, Artificial Cells, and Artificial Organs·T M Chang
Nov 1, 1978·Artificial Organs·T M Chang
Feb 26, 2016·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Wee-Keat CheahFei-Yee Yeoh
Aug 6, 2000·Artificial Cells, Blood Substitutes, and Immobilization Biotechnology·Y YuH Gu
Apr 27, 2021·Liver International : Official Journal of the International Association for the Study of the Liver·Sharon DeMorrowChristopher F Rose

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.