Ascarosides Promote the Prevalence of Ophiostomatoid Fungi and an Invasive Pathogenic Nematode, Bursaphelenchus xylophilus

Journal of Chemical Ecology
Lilin ZhaoJiang Hua Sun

Abstract

Understanding the coevolution of pathogens and their associated mycoflora depend upon a proper elucidation of the basis of their chemical communication. In the case of pine wilt disease, the mutual interactions between cerambycid beetles, invasive pathogenic nematodes, (Bursaphelenchus xylophilus) and their symbiotic ophiostomatoid fungi provide a unique opportunity to understand the role of small molecules in mediating their chemical communication. Nematodes produce ascarosides, a highly conserved family of small molecules that serve essential functions in nematode biology and ecology. Here we demonstrated that the associated fungi, one of the key natural food resources of pine wood nematodes, can detect and respond to these ascarosides. We found that ascarosides significantly increase the growth of L. pini-densiflorae and Sporothrix sp. 1, which are native fungal species in China that form a symbiotic relationship with pinewood nematodes. Hyphal mass of L. pini-densiflorae increased when treated with asc-C5 compared to other ophiostomatoid species. Field results demonstrated that in forests where higher numbers of PWN were isolated from beetle galleries, L. pini-densiflorae had been prevalent; the same results were confirmed ...Continue Reading

References

May 10, 2007·Molecular Biology and Evolution·Koichiro TamuraSudhir Kumar
Jun 15, 2007·Nature Chemical Biology·Rebecca A ButcherJon Clardy
Sep 16, 2008·Proceedings of the National Academy of Sciences of the United States of America·Rebecca A ButcherJon Clardy
Apr 17, 2012·Current Biology : CB·Andrea ChoePaul W Sternberg
Jun 16, 2012·PloS One·Fatma KaplanPeter E Teal
Nov 20, 2012·Angewandte Chemie·Neelanjan BoseFrank C Schroeder
Dec 6, 2012·Proceedings of the National Academy of Sciences of the United States of America·Andrea ChoeArthur S Edison
Dec 19, 2012·Current Biology : CB·Yen-Ping HsuehPaul W Sternberg
May 15, 2013·Annual Review of Phytopathology·Kazuyoshi Futai
Mar 17, 2015·Proceedings of the National Academy of Sciences of the United States of America·Xinxing ZhangRebecca A Butcher
Sep 1, 1983·Annual Review of Phytopathology·Y Mamiya
Jul 24, 2015·Nature Communications·Patricia ManosalvaDaniel F Klessig

❮ Previous
Next ❯

Citations

Apr 11, 2019·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Lian-Ming LiangKe-Qin Zhang

❮ Previous
Next ❯

Software Mentioned

BLAST

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.