Ascending propriospinal afferents to area X (substantia grisea centralis) of the spinal cord in the rat

Experimental Brain Research
M Matsushita

Abstract

Area X (the tenth area) of the spinal cord is a region surrounding the central canal and extending throughout the spinal cord length. Using anterograde and retrograde labeling techniques, ascending propriospinal projections to area X were examined in the rat. For anterograde tracing of axons, biotinylated dextran was injected into middle-thoracic, lumbar, or sacral-caudal segments. Unilateral injections resulted in bilateral labeling of terminals in area X of all segments rostral to the injections. The distribution of labeled terminals was conspicuous in regions dorsal and lateral to the central canal. The labeled axons were derived from the ventrolateral and the lateral cord. They coursed through lamina VII, giving off terminal axons. While giving off terminal axons in area X, they coursed further rostrally or caudally along the central canal or crossed over the central canal to terminate in the contralateral area X. Possible cells of origin of these ascending afferents were examined after injections of wheat germ agglutinin-horseradish peroxidase into regions surrounding the central canal (area X) at the cervical or thoracic level. Retrogradely labeled neurons were consistently seen in area X, and laminae VII and VIII of the ...Continue Reading

Citations

Mar 17, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Adrian A CameronAlexander G Rabchevsky
Sep 21, 2007·Journal of Neuropathology and Experimental Neurology·Sarah M McKayElspeth M McLachlan
Apr 3, 2003·The European Journal of Neuroscience·Jason R PotasRichard Bandler
Jul 13, 2002·The Journal of Comparative Neurology·Patrick D WallMatt S Ramer
Dec 6, 2017·Journal of Neurotrauma·Khalid C EldahanAlexander G Rabchevsky
Nov 2, 2017·Neural Regeneration Research·Hisham Sharif, Shaoping Hou
Nov 30, 2019·Frontiers in Cellular Neuroscience·Felicia M MichaelAlexander G Rabchevsky

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