Ascorbic acid supplementation does not alter oxidative stress markers in healthy volunteers engaged in a supervised exercise program

Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme
Piyawan Bunpo, Tracy G Anthony

Abstract

The purpose of this study was to investigate the impact of ascorbic acid (AA) consumption on the oxidative stress status of untrained volunteers participating in a supervised exercise program. The study included 46 young adults (average age, 23.5 ± 0.59 years; 37 females, 9 males) who remained sedentary (n = 16) or participated in 30 min of outdoor aerobic running (n = 30) at an intensity corresponding to 65%-75% of maximum heart rate for 3 times per week for 12 weeks. Exercised subjects were randomly assigned to an exercise group without AA supplementation (control; n = 10) or received either 250 mg (n = 10) or 500 mg (n = 10) of AA supplementation previous to each exercise session. Blood samples were taken on day 0 and day 84 to evaluate metabolic profiles and antioxidant status. Sedentary subjects underwent in a single bout of aerobic running to determine total antioxidant status (TAS) and malondiadehyde (MDA) at pre- and postexercise with or without AA supplementation. No significant change in TAS was observed. Plasma MDA significantly increased at postexercise (P < 0.05), and AA supplementation decreased MDA level significantly (P < 0.05). After 3 months of exercise, there was no significant change in blood glucose, lipid ...Continue Reading

References

Jun 1, 1979·Analytical Biochemistry·H OhkawaK Yagi
Oct 1, 1991·The American Journal of Clinical Nutrition·K R DhariwalM Levine
Aug 1, 1984·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·H Wolters, A W Konings
Jan 1, 1984·Methods in Enzymology·H Aebi
Aug 6, 2000·The Biochemical Journal·S GiesegJ M Gebicki
Mar 17, 2001·Medicine and Science in Sports and Exercise·M B Reid
Jun 9, 2001·Molecular Membrane Biology·W J LiangS M Jarvis
Jan 5, 2002·Physiological Reviews·Wulf Dröge
Jul 24, 2002·Nutrition in Clinical Care : an Official Publication of Tufts University·Robert A Jacob, Gity Sotoudeh
Feb 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·B PETERKOFSKY, S UDENFRIEND
Dec 4, 2003·Free Radical Biology & Medicine·Jens LykkesfeldtHenrik E Poulsen
Jun 4, 2005·The Journal of Physiology·Mari-Carmen Gomez-CabreraJose Viña
Feb 17, 2006·Respiratory Physiology & Neurobiology·Melissa A Smith, Michael B Reid
Jul 11, 2006·Biochimica Et Biophysica Acta·Valeria Cizewski CulottaThomas V O'Halloran
Nov 4, 2006·Journal of Applied Physiology·Malcolm J JacksonJesus Palomero
May 1, 2007·Experimental Gerontology·Li Li Ji
Oct 17, 2008·Physiological Reviews·Scott K Powers, Malcolm J Jackson
Jan 16, 2009·Dynamic Medicine : DM·Kelsey Fisher-Wellman, Richard J Bloomer
May 13, 2009·Proceedings of the National Academy of Sciences of the United States of America·Michael RistowMatthias Blüher
Nov 3, 2009·Experimental Physiology·Scott K PowersErin E Talbert
Dec 10, 2009·Medicine and Science in Sports and Exercise·Tatiana Y WarrenSteven N Blair
Jul 24, 2010·American Journal of Epidemiology·Alpa V PatelMichael J Thun
Jan 11, 2011·Mutation Research·Thomas B KrystonAlexandros G Georgakilas
Apr 14, 2011·International Journal of Sports Physiology and Performance·Llion A RobertsJames P Morton
Jul 14, 2011·American Journal of Physiology. Endocrinology and Metabolism·Kazuhiko HigashidaDong-Ho Han
Mar 6, 2012·Preventive Medicine·Yolanda EscalanteAna M Domínguez

❮ Previous
Next ❯

Citations

Mar 17, 2017·The Cochrane Database of Systematic Reviews·Lena Al-KhudairyKaren Rees
Oct 27, 2017·The Journal of Sports Medicine and Physical Fitness·Diego Muñoz MarínMarcos Maynar
Jun 1, 2017·Current Opinion in Clinical Nutrition and Metabolic Care·Bastian KochlikDaniela Weber
Dec 15, 2017·The Cochrane Database of Systematic Reviews·Mayur K RanchordasJoseph T Costello
Jan 23, 2019·Journal of the International Society of Sports Nutrition·Manita YimcharoenPiyawan Bunpo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme
Mohamed Amine BouzidClaudine Fabre
Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine
H M MousaS A ElMougy
© 2022 Meta ULC. All rights reserved