Aspects on the accuracy of cerebral perfusion parameters obtained by dynamic susceptibility contrast MRI: a simulation study

Magnetic Resonance Imaging
Linda KnutssonRonnie Wirestam

Abstract

Several studies have indicated that deconvolution based on singular value decomposition (SVD) is a robust concept for retrieval of cerebral blood flow in dynamic susceptibility contrast (DSC) MRI. However, the behavior of the technique under typical experimental conditions has not been completely investigated. In the present study, cerebral perfusion was simulated using different temporal resolutions, different signal-to-noise ratios (S/Ns), different shapes of the arterial input function (AIF), different signal drops, and different cut-off levels in the SVD deconvolution. Using Zierler's area-to-height relationship in combination with the central volume theorem, calculations of regional cerebral blood volume (rCBV), regional cerebral blood flow (rCBF), and regional mean transit time (rMTT) were accomplished, based on simulated DSC-MRI signal curves corresponding to artery, gray matter (GM), white matter (WM), and ischemic tissue. Gaussian noise was added to the noise-free signal curves to generate different S/Ns. We studied image time intervals of 0.5, 1.0, 1.5, 2.0, 2.5, and 3.0 s, as well as different degrees of signal decrease. The singular-value threshold in the SVD procedure and the shape of the AIF were also varied. Incr...Continue Reading

References

Nov 1, 1992·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·W H PermanJ S Perlmutter
May 1, 1990·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·B R RosenT J Brady
Aug 1, 1986·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·W A EdelsteinR W Redington
Oct 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J L BoxermanR M Weisskoff
Nov 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·L OstergaardB R Rosen
Nov 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·L OstergaardB R Rosen
May 1, 1997·Journal of Magnetic Resonance Imaging : JMRI·J L BoxermanR M Weisskoff
Mar 17, 1999·Journal of Magnetic Resonance Imaging : JMRI·C Z SimonsenC Gyldensted
Mar 18, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·E P VonkenM A Viergever
Aug 10, 1999·Journal of Magnetic Resonance Imaging : JMRI·E J VonkenM A Viergever
Oct 3, 1999·Journal of Magnetic Resonance Imaging : JMRI·J L Evelhoch
May 9, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R WirestamF Ståhlberg
Apr 23, 2002·NMR in Biomedicine·Linda AnderssonFreddy Ståhlberg
Apr 30, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jussi PerkiöLeif Østergaard
Sep 5, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·I K AndersenL K Hansen
Jan 2, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Michael R SmithRichard Frayne
Aug 27, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Matthias J P van OschChris J G Bakker

❮ Previous
Next ❯

Citations

Feb 1, 2012·Cephalalgia : an International Journal of Headache·Enrico B ArkinkMark C Kruit
Aug 24, 2012·AJR. American Journal of Roentgenology·Oleg S Pianykh
Feb 3, 2016·NMR in Biomedicine·Kawin SetsompopJonathan R Polimeni
Jun 2, 2011·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Lisa WillatsFernando Calamante
Apr 16, 2015·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Francesca ZanderigoR Todd Ogden
Jan 21, 2010·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Atle Bjørnerud, Kyrre E Emblem
Apr 21, 2011·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Kyrre E EmblemA Gregory Sorensen
Dec 20, 2005·Neuroimaging Clinics of North America·Ona WuA Gregory Sorensen
Mar 9, 2006·Journal of Magnetic Resonance Imaging : JMRI·Linda KnutssonRonnie Wirestam
Sep 1, 2007·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Fernando CalamanteMatthias J P van Osch
Mar 1, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Efrosini Z PapadakiThomas G Maris
Jan 21, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Amit MehndirattaMichael A Chappell
Apr 25, 2015·AJNR. American Journal of Neuroradiology·K WelkerUNKNOWN American Society of Functional Neuroradiology MR Perfusion Standards and Practice Subcommittee of the ASFNR Clinical Practic
Oct 3, 2013·Progress in Nuclear Magnetic Resonance Spectroscopy·Fernando Calamante
Oct 10, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Junjie WuDeqiang Qiu
Sep 29, 2009·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Tokunori Kimura, Hiroshi Kusahara
Nov 2, 2005·Journal of Magnetic Resonance Imaging : JMRI·Thomas E ConturoJoanne Markham
Jan 27, 2017·Journal of Clinical Imaging Science·Abhishek ChaturvediLee M Mitsumori
May 10, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Mary Kate ManhardKawin Setsompop
Aug 9, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Chau VuJohn C Wood
Mar 9, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Xingfeng ShaoLirong Yan
Aug 1, 2020·Brain Imaging and Behavior·Efrosini PapadakiPanagiotis Simos
Jun 10, 2020·Neuro-oncology·Jerrold L BoxermanUNKNOWN Jumpstarting Brain Tumor Drug Development Coalition Imaging Standardization Steering Committee
Nov 18, 2020·Physics in Medicine and Biology·Ingrid DigernesKyrre E Emblem
Aug 21, 2021·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Ashley M StokesC Chad Quarles

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Related Papers

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
H L LiuJ H Gao
Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
M J van OschC J Bakker
Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
I K AndersenL K Hansen
Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
F CalamanteAlan Connelly
© 2022 Meta ULC. All rights reserved