Aspergillus section Fumigati: antifungal susceptibility patterns and sequence-based identification.

Antimicrobial Agents and Chemotherapy
L Alcazar-FuoliJ L Rodriguez-Tudela

Abstract

This study analyzed 28 Aspergillus strains belonging to the section Fumigati that were isolated from clinical samples in Spain. All isolates sporulated slowly and were unable to grow at 48 degrees C. Phylogenetic analysis based on sequencing of partial sequences of the beta-tubulin and rodlet A genes was used to classify the 28 strains into six different clades (Neosartorya hiratsukae, Neosartorya pseudofischeri, Aspergillus viridinutans, Aspergillus lentulus, Aspergillus fumigatiaffinis, and Aspergillus fumisynnematus). Antifungal susceptibility testing showed heterogeneous patterns and grouped the strains together by species. Most A. lentulus and A. fumigatiaffinis isolates showed high MICs of amphotericin B (geometric mean [GM] MICs, >or=4.5 microg/ml), itraconazole (GM MICs, >or=6 microg/ml), voriconazole (GM MICs, >or=3 microg/ml), and ravuconazole (GM MICs, >or=3 microg/ml); N pseudofischeri and A. viridinutans showed high MICs of itraconazole (GM MICs, >or=8 microg/ml), voriconazole (GM MICs, >or=3.33 microg/ml), and ravuconazole (GM MICs, >or=2 microg/ml); and N. hiratsukae and A. fumisynnematus were susceptible to all the antifungals tested. In conclusion, a number of different species whose morphological features rese...Continue Reading

References

Dec 1, 1996·Applied and Environmental Microbiology·J VargaZ Kozakiewicz
Apr 9, 1999·Clinical Microbiology Reviews·J P Latgé
Apr 4, 2000·Journal of Clinical Microbiology·L WangK Nishimura
Feb 27, 2001·The Journal of Antimicrobial Chemotherapy·E DannaouiF Persat
Jan 18, 2002·Antimicrobial Agents and Chemotherapy·J Mosquera, D W Denning
Apr 17, 2002·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D P Kontoyiannis, G P Bodey
Aug 27, 2002·Emerging Infectious Diseases·Josep GuarroArnaldo Lopes Colombo
Feb 27, 2003·Antimicrobial Agents and Chemotherapy·T M Diaz-GuerraJ L Rodriguez-Tudela
Apr 26, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·John R PerfectElizabeth Johnson
Sep 25, 2003·Antimicrobial Agents and Chemotherapy·Alicia Gomez-LopezManuel Cuenca-Estrella
Feb 10, 2004·Journal of Clinical Microbiology·H JärvP Naaber
Mar 30, 2004·Antimicrobial Agents and Chemotherapy·S Arunmozhi BalajeeKieren A Marr
Jun 11, 2004·Antonie van Leeuwenhoek·J VargaY Horie
Aug 26, 2004·Antimicrobial Agents and Chemotherapy·William J SteinbachDaniel K Benjamin
Mar 10, 2005·Eukaryotic Cell·S Arunmozhi BalajeeKieren A Marr
Apr 9, 2005·Revista iberoamericana de micología·Aitor RementeriaJavier Garaizar
Jul 26, 2005·Infection and Immunity·Dimitrios I TsitsigiannisNancy P Keller
Sep 29, 2005·Antimicrobial Agents and Chemotherapy·Juan L Rodriguez-TudelaManuel Cuenca-Estrella
Oct 4, 2005·British Journal of Haematology·Cornelia Lass-FlörlDavid Nachbaur
Dec 8, 2005·Journal of Clinical Microbiology·S Arunmozhi BalajeeKieren A Marr
Jan 27, 2006·Antimicrobial Agents and Chemotherapy·Laura Alcazar-FuoliJuan L Rodriguez-Tudela
Feb 2, 2006·International Journal of Systematic and Evolutionary Microbiology·Seung-Beom HongRobert A Samson
Oct 13, 2006·Eukaryotic Cell·S Arunmozhi BalajeeKieren A Marr
Nov 15, 2006·Antimicrobial Agents and Chemotherapy·Ana Alastruey-IzquierdoJuan L Rodriguez-Tudela
Feb 9, 2007·Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology·Takashi YaguchiKazuko Nishimura
Apr 6, 2007·The New England Journal of Medicine·Paul E VerweijWillem J G Melchers
May 29, 2007·Microbiology·M T HedayatiD W Denning
Sep 1, 2006·Medical Mycology·David W Denning
Sep 1, 2006·Medical Mycology·Robert A SamsonJens C Frisvad
Sep 1, 2006·Medical Mycology·C Lass-FlörlJ L Rodriguez-Tudela

❮ Previous
Next ❯

Citations

May 5, 2011·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·K L MortensenM C Arendrup
Feb 19, 2011·Avian Pathology : Journal of the W.V.P.A·Lieven Van WaeyenbergheAn Martel
Apr 23, 2009·The Journal of Antimicrobial Chemotherapy·Paul E Verweij, Johan Maertens
Sep 10, 2010·Current Opinion in Infectious Diseases·Koichi IzumikawaShigeru Kohno
Jul 23, 2008·Antimicrobial Agents and Chemotherapy·Maiken Cavling ArendrupCornelia Lass-Flörl
May 15, 2013·Antimicrobial Agents and Chemotherapy·A Alastruey-IzquierdoUNKNOWN FILPOP Study Group
Jul 29, 2009·Antimicrobial Agents and Chemotherapy·Laura Alcazar-FuoliJuan L Rodriguez-Tudela
Sep 2, 2010·Antimicrobial Agents and Chemotherapy·Klaus Leth MortensenMaiken Cavling Arendrup
Sep 22, 2010·Antimicrobial Agents and Chemotherapy·Janet F StaabKieren A Marr
Mar 5, 2009·Antimicrobial Agents and Chemotherapy·L A BeernaertA Martel
Nov 30, 2011·Antimicrobial Agents and Chemotherapy·Pierre-Régis BurgelAndré Paugam
Sep 29, 2011·Antimicrobial Agents and Chemotherapy·Emilia MelladoJuan L Rodriguez-Tudela
May 8, 2013·Eukaryotic Cell·Sameira S SwilaimanPaul S Dyer
May 1, 2009·Journal of Clinical Microbiology·Janet F StaabKieren A Marr
Jul 4, 2008·Journal of Clinical Microbiology·Jae-Ik Han, Ki-Jeong Na
Aug 21, 2009·Journal of Clinical Microbiology·M A PfallerUNKNOWN Clinical and Laboratory Standards Institute Antifungal Testing Subcommittee
Jan 25, 2013·Journal of Clinical Microbiology·Kathy MalejczykStephanie W Smith
Apr 23, 2011·BMC Microbiology·Rita SerranoRicardo Araujo
Jul 31, 2012·BMC Microbiology·Ricardo AraujoLeonor Gusmão
Sep 16, 2009·Emerging Infectious Diseases·Donald C VinhSteven M Holland
Sep 14, 2013·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·P E B VerwerW W J van de Sande
Jul 29, 2010·Medical Mycology·Jan W M Van Der LindenPaul E Verweij
Aug 28, 2010·Medical Mycology·Susan Julie Howard, Maiken Cavling Arendrup
Nov 12, 2010·Medical Mycology·Françoise SymoensJean-Philippe Bouchara
Apr 30, 2011·Future Microbiology·David S Perlin
Jan 22, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Elisabeth ParamythiotouGeorge Dimopoulos
Feb 9, 2011·Medical Mycology·Danina CoelhoMaria Dolores Pinheiro
Feb 25, 2014·The Veterinary Journal·Jessica J TalbotVanessa R Barrs
Apr 10, 2014·Biomarkers in Medicine·Gemma JohnsonStephen A Bustin
Jul 27, 2014·Diagnostic Microbiology and Infectious Disease·J V Fernandez-MolinaA Rementeria
Jul 30, 2014·Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy·Seyedmojtaba SeyedmousaviPaul E Verweij
Sep 6, 2011·Medical Mycology Journal·Takashi Yaguchi

❮ Previous
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