Aspergillus spp. invasive external otitis: favourable outcome with a medical approach

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
E MarchionniFanny Lanternier

Abstract

Aspergillus spp. invasive external otitis (IEO) is a rare infection. We performed a seven-year, single-centre retrospective study from 2007 to 2014 including all patients with proven Aspergillus spp. IEO. Twelve patients were identified. All patients had a poorly controlled diabetes mellitus and one underwent solid organ transplant. The most frequently isolated species was Aspergillus flavus (n = 10) and voriconazole was the first-line therapy in all cases, with a median length of treatment of 338.5 days (158-804 days). None of the patients underwent extensive surgery. The clinical outcome was excellent. However, otological sequelae were reported, including hearing impairment (n = 7) and facial palsy (n = 3).

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Citations

Mar 29, 2018·QJM : Monthly Journal of the Association of Physicians·E MarechalM Blot
Jan 29, 2021·Journal of Otology·Mehdi HasnaouiKhalifa Mighri
Mar 7, 2020·European Annals of Otorhinolaryngology, Head and Neck Diseases·L NoroyJ Saison
Aug 7, 2021·Enfermedades Infecciosas Y Microbiologia Clinica·Sandra Scarleth Mendoza-LizardoJesús Fortún
Nov 8, 2020·Enfermedades infecciosas y microbiología clínica·Sandra Scarleth Mendoza-LizardoJesús Fortún

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