Asphyxia causes ultrasonographic D-shaping of the left ventricle - an experimental porcine study

Acta Anaesthesiologica Scandinavica
A H SørensenP Juhl-Olsen

Abstract

In critical care, early diagnosis and correct treatment are of the utmost importance. Focused ultrasonography has gained acceptance as a pivotal tool for this by elucidating the underlying pathology. For example, massive pulmonary embolism is characterised by right ventricular dilatation. However, theoretically these characteristics might also be generated by asphyxia and the consequent hypoxia. We aimed to evaluate the ultrasonographic characteristics of asphyxia in a porcine model. Nineteen (13 intervention, 6 control) piglets were subjected to asphyxia until cardiac arrest, by disconnecting the ventilator tube. Ultrasonographic short-axis cine loops of the left ventricle were obtained every 30 seconds. The left ventricular (LV) eccentricity index (index of LV D-shaping) was quantified along with LV end-diastolic/end-systolic areas. Invasive pressures were measured throughout. The LV eccentricity index increased from 1.14 (1.10-1.31) to 1.86 (1.48-2.38), (P = 0.002), after 1.5 min, receded thereafter to baseline levels followed by a second increase after 5.5 min. LV end-diastolic area decreased from 11.6 cm(2) (11.1-13.2) to 6.3 cm(2) (3.3 -11.0) after 2.0 min (P = 0.009). Subsequently, values returned to the baseline level. ...Continue Reading

References

May 1, 1991·International Journal of Cardiology·R M OliverD G Waller
Dec 1, 1986·American Heart Journal·W KasperH Just
Apr 1, 1985·Journal of the American College of Cardiology·T RyanW F Armstrong
Sep 1, 1960·Journal of Applied Physiology·J L WHITTENBERGERH G BORST
Dec 15, 2004·European Journal of Anaesthesiology·M B JensenM B Schmidt
Feb 1, 2007·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Roger HainsworthMaria Rivera-Chira
Sep 14, 2007·Respiratory Physiology & Neurobiology·Frank ReichenbergerHossein A Ghofrani
Oct 3, 2007·European Journal of Applied Physiology·Jesper KjaergaardRobert P Frantz
Dec 1, 2009·Emergency Medicine Clinics of North America·Phillips PereraDiku Mandavia
Aug 1, 1947·The American Journal of Physiology·H L MOTLEY, A COURNAND
Nov 3, 2010·Acta Anaesthesiologica Scandinavica·C A FrederiksenE Sloth
Nov 30, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Arthur J LabovitzKevin Wei
Mar 15, 2011·Circulation. Cardiovascular Imaging·Sherif F NaguehJerry D Estep
Dec 4, 2013·Scandinavian Cardiovascular Journal : SCJ·Lærke Kamstrup ChristiansenErik Sloth

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Citations

Mar 16, 2017·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Viktor Kromann RinggårdPeter Juhl-Olsen
Dec 16, 2017·American Journal of Respiratory and Critical Care Medicine·Ryan W MorganRobert A Berg
Oct 20, 2018·Echocardiography·Henrik Lynge HovgaardPeter Juhl-Olsen
May 1, 2018·A&A Practice·Peter Juhl-OlsenAnni Nørgaard Jeppesen

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