Aspiration and Non-Aspiration Pneumonia in Hospitalized Children With Neurologic Impairment

Pediatrics
Joanna ThomsonJay G Berry

Abstract

Children with neurologic impairment (NI) are commonly hospitalized for different types of pneumonia, including aspiration pneumonia. We sought to compare hospital management and outcomes of children with NI diagnosed with aspiration versus nonaspiration pneumonia. A retrospective study of 27 455 hospitalized children aged 1 to 18 years with NI diagnosed with pneumonia from 2007 to 2012 at 40 children's hospitals in the Pediatric Health Information System database. The primary exposure was pneumonia type, classified as aspiration or nonaspiration. Outcomes were complications (eg, acute respiratory failure) and hospital utilization (eg, length of stay, 30-day readmission). Multivariable regression was used to assess the association between pneumonia type and outcomes, adjusting for NI type, comorbid conditions, and other characteristics. In multivariable analysis, the 9.7% of children diagnosed with aspiration pneumonia experienced more complications than children with nonaspiration pneumonia (34.0% vs 15.2%, adjusted odds ratio [aOR] 1.2 (95% confidence interval [CI] 1.1-1.3). Children with aspiration pneumonia had significantly longer length of stay (median 5 vs 3 days; ratio of means 1.2; 95% CI 1.2-1.3); more ICU transfers (4...Continue Reading

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Citations

Nov 3, 2016·Hospital Pediatrics·Alexander W HirschMark I Neuman
Oct 17, 2018·JAMA Otolaryngology-- Head & Neck Surgery·Daniel R DuncanRachel L Rosen
Jan 1, 2020·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Joanna ThomsonSamir S Shah
Sep 9, 2020·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Christopher J Russell, Andrew A White
Jan 10, 2018·Pediatric Pulmonology·Christopher J RussellJay G Berry
Jun 26, 2020·Expert Review of Anti-infective Therapy·Anand GourishankarEllen Lin
Feb 23, 2021·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Jessica L MarkhamJay G Berry
Aug 22, 2021·Developmental Medicine and Child Neurology·Florentine V SchepersLenie van den Engel-Hoek
Sep 1, 2021·Developmental Medicine and Child Neurology·Catherine DiskinEyal Cohen
Oct 31, 2021·Hospital Pediatrics·Amanda WarnimentJoanna Thomson

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