PMID: 8952850Jan 1, 1996Paper

Aspiration needle biopsy refines preoperative diagnosis of thyroid nodules defined at fine needle aspiration as microfollicular nodule

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
A CarpiGiancarlo Di Coscio

Abstract

The aim of this paper was to verify the hypothesis that large needle biopsy performed preoperatively can refine preoperative fine needle aspiration (FNA) cytological diagnoses of microfollicular nodules. Since 1980 we have been using FNA and aspiration needle biopsy (ANB) (18 or 16 gauge needles) to select for surgery all euthyroid patients with palpable thyroid nodules referred to our department. From 1980 to 1994, 6,124 patients (12% male, 88% female) with thyroid nodules (71% single, 29% multiple) were examined by FNA; 29% of these patients were also examined preoperatively by ANB histology. Of all the nodule patients examined, 371 received a preoperative FNA diagnosis of microfollicular nodule. Two hundred and fifty-four of these nodules (68%) were also examined preoperatively by ANB. Unsatisfactory ANB specimens constituted 17% of cases; pure microfollicular structure was confirmed by ANB in 36% of the nodules; ANB showed the remaining 47% to contain a macrofollicular component, thus suggesting a benign hyperplastic lesion. Twelve nodules which were found to be microfollicular at FNA cytology and micro-macrofollicular at ANB were excised and were subsequently determined as benign at definitive postoperative histology. Thes...Continue Reading

References

May 1, 1982·Journal of Clinical Pathology·G Bussolati
Apr 1, 1982·American Journal of Surgery·W B GoldfarbR H Nishyama
Aug 1, 1930·Annals of Surgery·H E Martin, E B Ellis

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Citations

Sep 16, 2000·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·D CasaraG Saladini
Sep 16, 2000·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·A Carpi, A Nicolini
Nov 11, 1998·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·A CarpiG Di Coscio
Oct 16, 1999·American Journal of Clinical Oncology·A CarpiA Sagripanti
Nov 19, 1997·Journal of Endocrinological Investigation·R V García-MayorE Fluiters
Apr 20, 2007·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Jae Won KimYoung Up Cho
Oct 5, 2001·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·D BarbaroG Soriani

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