PMID: 5284361Jun 23, 1971

Aspirin selectively inhibits prostaglandin production in human platelets

Nature: New Biology
J B Smith, A L Willis

Abstract

No abstract listed.

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Aspirin enhances the sensitivity of human platelet 12-lipoxygenase to inhibition by 15-HETE, an endogenous regulator

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Dec 28, 1999·European Journal of Pharmacology·Y KatoJ Seki

Low-dose aspirin treatment improves ovarian responsiveness, uterine and ovarian blood flow velocity, implantation, and pregnancy rates in patients undergoing in vitro fertilization: a prospective, randomized, double-blind placebo-controlled assay

May 7, 1999·Fertility and Sterility·M RubinsteinE Polak de Fried

Antiplatelet and anticoagulant effects of "HN-11 500," a selective thromboxane receptor antagonist

Jul 18, 2001·Thrombosis Research·J F SchenkH K Breddin

The mechanism of action of aspirin

Nov 1, 2003·Thrombosis Research·J R Vane, Regina M Botting

Combination of two doses of acetyl salicylic acid: experimental study of arterial thrombosis

Aug 7, 1998·Thrombosis Research·E Belougne-MalfattiC Doutremepuich

Aspirin treatment improves bladder function after outlet obstruction in rabbits

Oct 13, 2001·Urology·A SchröderP A Longhurst

Aspirin prophylaxis in migraine

Dec 2, 1978·Lancet·B P O'Neill, J D Mann

Congenital deficiency of thromboxane and prostacyclin

Apr 26, 1980·Lancet·F I ParetiG Galli

Effects of 11-week increases in dietary eicosapentaenoic acid on bleeding time, lipids, and platelet aggregation

Nov 28, 1981·Lancet·M Thorngren, A Gustafson

Differential inhibition by low-dose aspirin of human venous prostacyclin synthesis and platelet thromboxane synthesis

May 2, 1981·Lancet·S P HanleyS Heptinstall

Pharmacology of antiplatelet drugs and clinical trials on thrombosis prevention: a difficult link

Oct 30, 1982·Lancet·G De GaetanoV Bertelè

Aspirin: additional mechanisms of action

May 26, 1984·Lancet·W J McDonald-Gibson, R G McDonald-Gibson

Hallucinations in a child after drinking triprolidine/pseudoephedrine linctus

May 26, 1984·Lancet·F M Ackland

Primary prevention of vascular disease by aspirin

May 14, 1988·Lancet·G De Gaetano

The safety profile, tolerability, and effective dose range of rofecoxib in the treatment of rheumatoid arthritis. Phase II Rofecoxib Rheumatoid Arthritis Study Group

Nov 24, 1999·Clinical Therapeutics·T J SchnitzerE W Ehrich

Cyclooxygenase inhibitors--current status and future prospects

Apr 20, 2001·European Journal of Medicinal Chemistry·G Dannhardt, W Kiefer

The effect of arachidonic acid on the aggregability of human platelet rich plasma

Feb 1, 1982·Prostaglandins, Leukotrienes, and Medicine·M L DahlP Uotila

Subacute and chronic oral toxicity of lornoxicam in cynomolgus monkeys

May 1, 1997·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·E AtzpodienS Radhofer-Welte

Evaluation of chronic oral toxicity and carcinogenic potential of lornoxicam in rats

Dec 31, 1997·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·G Pohlmeyer-EschS Radhofer-Welte

Carbon tetrachloride-induced lipid peroxidation: eicosanoid formation and their regulation by antioxidant nutrients

Jun 25, 2003·Toxicology·Samar Basu

A perspective on the potential problems with aspirin as an antithrombotic agent: a comparison of studies in an animal model with clinical trials

Feb 11, 1999·Journal of the American College of Cardiology·J D FoltsJ E Muller

Design, synthesis and biological evaluation of benzimidazole/benzothiazole and benzoxazole derivatives as cyclooxygenase inhibitors

Mar 18, 2003·Bioorganic & Medicinal Chemistry Letters·R ParamashivappaA Srinivasa Rao

Structural basis for selective inhibition of COX-2 by nimesulide

Jan 30, 1999·Bioorganic & Medicinal Chemistry·G F FabiolaK Nagarajan

Studies on the anti-inflammatory and anti-nociceptive effects of melatonin in the rat

Sep 11, 2002·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Siham M El-ShenawyMahmoud S Arbid

Pharmacodynamics and pharmacokinetics of tolfenamic acid in ruminating calves: evaluation in models of acute inflammation

Jun 25, 1998·The Veterinary Journal·P LeesG Gettinby

Prostaglandins and other cyclooxygenase-dependent arachidonic acid metabolites and the kidney in liver disease

Nov 25, 2003·Prostaglandins & Other Lipid Mediators·Joan Clària, Vicente Arroyo

The effects of salicylate on bacteria

Nov 25, 2000·The International Journal of Biochemistry & Cell Biology·C T PriceJ E Gustafson

Cyclo-oxygenase-1 and cyclo-oxygenase-2 and cardiovascular system

Feb 6, 2002·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·M LettinoM Mariani

COX isoforms in the cardiovascular system: understanding the activities of non-steroidal anti-inflammatory drugs

Feb 18, 2006·Nature Reviews. Drug Discovery·Jane A Mitchell, Timothy D Warner

Aspirin for primary prevention of cardiovascular disease in diabetes mellitus

Sep 22, 2010·Nature Reviews. Endocrinology·Michael Pignone, Craig D Williams

In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin

Apr 27, 1999·British Journal of Pharmacology·D M Dirig, Tony L Yaksh

Comparative antiplatelet effects of aspirin, vapiprost and GR144053, a GPIIb/IIIa antagonist, with a special reference to the role of platelet microaggregates

Aug 24, 1999·British Journal of Pharmacology·H MatsunoT Uematsu

Cyclo-oxygenase-2 inhibition and exacerbation of myocardial dysfunction--protection with nitric oxide?

Mar 22, 2002·British Journal of Pharmacology·Gordon Letts

Pharmacokinetics and pharmacodynamics of sibrafiban alone or in combination with ticlopidine and aspirin

Mar 16, 2000·British Journal of Clinical Pharmacology·B WittkeS J Machin

A pharmacodynamic and pharmacokinetic study with vedaprofen in an equine model of acute nonimmune inflammation

Jun 18, 1999·Journal of Veterinary Pharmacology and Therapeutics·P LeesP V Rens

Action of salicylates

Feb 10, 1972·The New England Journal of Medicine·S M Krane

Cyclic AMP and platelet function

Feb 17, 1972·The New England Journal of Medicine·E W Salzman

A simple nonradioisotope technic for the determination of platelet life-span

Jun 19, 1975·The New England Journal of Medicine·M J StuartF A Oski

Neurotransmitters and the normal and ischemic cerebral circulation

Oct 16, 1975·The New England Journal of Medicine·N T ZervasM Negoro

Letter: Lack of drug precipitation in serum and plasma (in vitro)

Feb 26, 1976·The New England Journal of Medicine·S J Turco, R Newman

Increased synthesis of prostaglandin-E-like material by platelets from patients with diabetes mellitus

Dec 15, 1977·The New England Journal of Medicine·Perry V HalushkaJ A Colwell

Antiplatelet therapy (first of two parts)

Jun 15, 1978·The New England Journal of Medicine·H J Weiss

Inhibition of prostacyclin and platelet thromboxane A2 after low-dose aspirin

Jan 8, 1981·The New England Journal of Medicine·F E PrestonC J Stoddard

Aspirin to prevent arterial thrombosis

Jul 8, 1982·The New England Journal of Medicine·E W Salzman

Differential inhibition by aspirin of vascular and platelet prostaglandin synthesis in atherosclerotic patients

Apr 7, 1983·The New England Journal of Medicine·B B WekslerW A Gay

Prostaglandin endoperoxides. A new concept concerning the mode of action and release of prostaglandins

Oct 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·M HambergB Samuelsson

Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation

Feb 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·M HambergB Samuelsson

Acetylation of prostaglandin synthase by aspirin

Aug 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·G J RothPhilip W Majerus

Sensitivity of fatty acid cyclooxygenase from human aorta to acetylation by aspirin

Oct 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·J W BurchPhilip W Majerus

Ionophore A-23187- and thrombin-induced platelet aggregation: independence from cycloxygenase products

Feb 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·E G LapetinaP Cuatrecasas

Aspirin-like drugs interfere with arachidonate metabolism by inhibition of the 12-hydroperoxy-5,8,10,14-eicosatetraenoic acid peroxidase activity of the lipoxygenase pathway

Aug 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·M I SiegelP Cuatrecasas

13-Azaprostanoic acid: a specific antagonist of the human blood platelet thromboxane/endoperoxide receptor

Aug 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·G C Le BretonPerry V Halushka

Arachidonate metabolism via lipoxygenase and 12L-hydroperoxy-5,8,10,14-icosatetraenoic acid peroxidase sensitive to anti-inflammatory drugs

Jan 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·M I SiegelP Cuatrecasas

Direct evidence for the existence of a neutrophil-derived platelet activator (neutrophilin)

Nov 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·M ChignardJ B Smith

Pharmacokinetics of aspirin and salicylate in relation to inhibition of arachidonate cyclooxygenase and antiinflammatory activity

Mar 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·G A HiggsJ R Vane

Aspirin inhibits interleukin 1-induced prostaglandin H synthase expression in cultured endothelial cells

Mar 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·K K WuD S Loose-Mitchell

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain

Dec 6, 1994·Proceedings of the National Academy of Sciences of the United States of America·K SeibertP C Isakson

Metabolism and excretion of imrecoxib in rat

Jul 21, 2006·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·Hai-yan XuDa-fang Zhong

Eicosanoids in health and in disease: an appraisal

Jan 1, 1985·The Veterinary Quarterly·A J Higgins

Aspirin and postoperative bleeding after coronary artery bypass grafting

May 30, 2002·Annals of Surgery·Victor A FerrarisRobert M Mentzer

Cox-2-specific inhibitors: definition of a new therapeutic concept

Apr 17, 2001·American Journal of Therapeutics·K M VerburgP C Isakson

Adventures in vascular biology: a tale of two mediators

Apr 22, 2006·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·S Moncada

The influence of combined treatment with propranolol and acetylsalicylic acid on platelet aggregation in coronary heart disease

Mar 1, 1979·British Journal of Clinical Pharmacology·I KeberM Stegnar

Effects of non-steroidal anti-inflammatory drugs on prostacyclin and thromboxane biosynthesis in patients with mild essential hypertension

Oct 1, 1990·British Journal of Clinical Pharmacology·P MinuzJ M Ritter

The effects of varying doses of aspirin on human platelet activation induced by PAF, collagen and arachidonic acid

Jan 1, 1992·British Journal of Clinical Pharmacology·M L TaylorP J Thompson

Tenidap, but not nonsteroidal anti-inflammatory drugs, inhibits T-cell proliferation and cytokine induction

Dec 1, 1995·Scandinavian Journal of Immunology·R J DolhainA M Miltenburg

Perspectives in dermatology: Great Britain (1972-1974)

Dec 1, 1975·International Journal of Dermatology·R M Mackie, J A Milne

The effect of acetylsalicylic acid on the peripheral and pulmonary vascular responses to thrombin

Jan 1, 1972·Acta Anaesthesiologica Scandinavica·K Rådegran

Prostaglandin F2alpha as a mediator of pulmonary changes during platelet aggregation

Jan 1, 1977·Acta Anaesthesiologica Scandinavica·K RådegranE Granström

Regulation of prostaglandin biosynthesis with flunixin meglumine in the bovine species

Feb 1, 1990·Zentralblatt für Veterinärmedizin. Reihe A·S AiumlamaiH Kindahl

Medullary ischaemia in experimental analgesic nephropathy--the pathogenesis of renal papillary necrosis

Dec 1, 1973·Australian and New Zealand Journal of Medicine·R S NanraP Kincaid-Smith

Analgesic abuse and kidney disease

Oct 1, 1976·Australian and New Zealand Journal of Medicine·J H Stewart, E D Gallery

The effect of indomethacin on plasma levels of prostaglandin F2alpha in women in labour

May 1, 1977·British Journal of Obstetrics and Gynaecology·H ZuckermanD Sklan

The inhibition by dexamethasone and disodium cromoglycate of anaphylactic bronchoconstriction in the rat

Sep 1, 1972·British Journal of Pharmacology·M K ChurchG W James

Output of prostaglandins from the rabbit kidney, its increase on renal nerve stimulation and its inhibition by indomethacin

Dec 1, 1972·British Journal of Pharmacology·H A Davis, E W Horton

Prostaglandins, oxygen tension and smooth muscle tone

Jul 1, 1972·British Journal of Pharmacology·A Eckenfels, J R Vane

Some effects of inhibiting endogenous prostaglandin formation on the responses of the cat spleen

Jan 1, 1973·British Journal of Pharmacology·S H FerreiraJ R Vane

The contribution of prostaglandin production to contractions of the isolated uterus of the rat

Aug 1, 1973·British Journal of Pharmacology·J R Vane, K I Williams

Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs

Sep 1, 1973·British Journal of Pharmacology·S H FerreiraJ R Vane

Inhibition of functional vasodilatation and prostaglandin formation in rabbit adipose tissue by indomethacin and aspirin

Feb 1, 1973·British Journal of Pharmacology·B Bowery, G P Lewis

Release of rabbit aorta contracting substance (RCS) and prostaglandins induced by chemical or mechanical stimulation of guinea-pig lungs

Oct 1, 1973·British Journal of Pharmacology·M A PalmerJ R Vane

Inhibition of the prostaglandin synthetase systems in ocular tissues by indomethacin

Feb 1, 1974·British Journal of Pharmacology·P Bhattacherjee, K E Eakins

Inhibition by non-steroid anti-inflammatory agents of rabbit aorta contracting activity generated in blood by slow reacting substance C

Apr 1, 1974·British Journal of Pharmacology·S H Ferreira, B B Vargaftig

Actions of putative transmitters in the chicken vagus nerve/oesophagus and Remak nerve/rectum preparations

Aug 1, 1974·British Journal of Pharmacology·A L Bartlet

A chemotactic role for prostaglandins released from polymorphonuclear leucocytes during phagocytosis

Apr 1, 1975·British Journal of Pharmacology·G A HiggsL J Youlten

Release of prostaglandin-like substances by Shigella endotoxin and its inhibition by non-steroidal anti-inflammatory compounds

Aug 1, 1975·British Journal of Pharmacology·P Bhattacherjee

Meiosis: a prostaglandin response that is not inhibited by aspirin

Sep 1, 1975·British Journal of Pharmacology·P G Dellow, T S Miles

The effect of aspirin on 5-hydroxytryptamine uptake and release by human platelets

May 1, 1976·British Journal of Pharmacology·F Rendu

Inhibition of peristalsis in guinea-pig isolated ileum and colon by drugs that block prostaglandin synthesis

Jul 1, 1976·British Journal of Pharmacology·A BennettH L Stockley

Prostaglandin antagonism by sodium p-benzyl-4-[1-oxo-2-(4-chlorobenzyl)-3-phenylpropyl]pheenyl phosphonate (N-0164)

Nov 1, 1976·British Journal of Pharmacology·K E EakinsR Schroer

The local antinociceptive and topical anti-inflammatory effects of propyl gallate in rodents

Dec 1, 1976·British Journal of Pharmacology·W J McDonald-GibsonC Schneider

Effects of aspirin-like drugs on canine gastric mucosal blood flow and acid secretion

Aug 1, 1977·British Journal of Pharmacology·A Bennett, B P Curwain

Prostaglandin F2alpha reduces the algesic effect of bradykinin by antagonizing the pain enhancing action of endogenously released prostaglandin E

Mar 1, 1977·British Journal of Pharmacology·H Juan, F Lembeck

Modification, by aspirin and indomethacin, of the haemodynamic and prostaglandin releasing effects of E. coli endotoxin in the dog

Oct 1, 1977·British Journal of Pharmacology·J R Fletcher, P W Ramwell

Prostaglandin production by macrophages and the effect of anti-inflammatory drugs

Aug 1, 1978·British Journal of Pharmacology·M A Bray, D Gordon

Vasodilatation and inhibition of mediator release represent two distinct mechanisms for prostaglandin modulation of acute mast cell-dependent inflammation

Mar 1, 1990·British Journal of Pharmacology·J Raud

5-Hydroxytryptamine and arachidonic acid metabolites modulate extensive platelet activation induced by collagen in cats in vivo

Apr 1, 1990·British Journal of Pharmacology·F De ClerckP A Janssen

Ca(2+)-dependent aggregation of rabbit platelets induced by maitotoxin, a potent marine toxin, isolated from a dinoflagellate

May 1, 1993·British Journal of Pharmacology·A WatanabeY Ohizumi

Haemostatic mechanism in the endometrium: role of cyclo-oxygenase products and coagulation factors

Mar 1, 1995·British Journal of Pharmacology·T J Gelety, G Chaudhuri

Inhibition of carrageenin-induced rat paw oedema by crotapotin, a polypeptide complexed with phospholipase A2

Feb 1, 1995·British Journal of Pharmacology·E C LanducciG de Nucci

Prostaglandins: physiology, biochemistry, pharmacology and clinical applications

Oct 1, 1978·Journal of Oral Pathology·T M Elattar

Prostanoids and leukotrienes in rheumatoid synovitis

Jan 1, 1994·Pharmacology & Toxicology·E Moilanen

Non-steroidal anti-inflammatory drugs and leucocyte emigration

Jul 1, 1972·The Journal of Pharmacy and Pharmacology·M Di RosaL Parente

Letter: Arachidonic acid lowers and indomethacin increases the blood pressure of the rabbit

Aug 1, 1973·The Journal of Pharmacy and Pharmacology·C Larsson, E Anggärd

Prostaglandins and the anti-inflammatory activities of aspirin and sodium salicylate

Jul 1, 1975·The Journal of Pharmacy and Pharmacology·M J SmithP N Elliott

Carrageenan and thrombin trigger prostaglandin synthetase-independent aggregation of rabbit platelets: inhibition by phospholipase A2 inhibitors

Apr 1, 1977·The Journal of Pharmacy and Pharmacology·B B Vargaftig

Salicylic acid fails to inhibit generation of thromboxane A2 activity in platelets after in vivo administration to the rat

Feb 1, 1978·The Journal of Pharmacy and Pharmacology·B B Vargaftig

Effect of carbenoxolone on lipolysis in rat adipose tissue

May 1, 1978·The Journal of Pharmacy and Pharmacology·B LambertC Jacquemin

Comparison of effects of aspirin and indomethacin on human platelet prostaglandin synthetase

Oct 1, 1977·Annals of the Rheumatic Diseases·D Crook, A J Collins

Prostaglandin production in arthritis

Aug 1, 1978·Annals of the Rheumatic Diseases·R A SturgeJ Morley

Bath-time itch

Jun 20, 1981·British Medical Journal

New light on inflammation

Jul 10, 1971·British Medical Journal

Modification by drugs of urinary fibrin/fibrinogen degradation products in glomerulonephritis

Jul 29, 1972·British Medical Journal·A R ClarksonJ S Robson

Effect of prostaglandin 15(R) 15 methyl-E2 methyl ester on aspirin and taurocholic acid-induced gastric mucosal haemorrhage in rats

Jan 1, 1976·Gut·H A CarmichaelK M Cochran

Distribution of prostaglandins in gastric and duodenal mucosa of healthy subjects and duodenal ulcer patients: effects of aspirin and paracetamol

Apr 1, 1981·Gut·S J KonturekA Kiec-Dembinska

Successful treatment of migraine attacks with intravenous injection of aspirin

Nov 1, 1985·Journal of Neurology, Neurosurgery, and Psychiatry·S NodaY Fukuda

Prostaglandin levels in blood plasma during asthmatic attacks in patients with aspirin idiosyncrasy

Jan 1, 1975·Postgraduate Medical Journal·J C DelaneyM J Silver

Nobel lecture. Adventures and excursions in bioassay--the stepping stones to prostacyclin

Dec 1, 1983·Postgraduate Medical Journal·J R Vane

Aspirin and other anti-inflammatory drugs

Sep 19, 2000·Thorax·S J Vane

Comparison of three inhaled non-steroidal anti-inflammatory drugs on the airway response to sodium metabisulphite and adenosine 5'-monophosphate challenge in asthma

Aug 1, 1996·Thorax·M WangA Tattersfield

The modulation of intra-articular inflammation, cartilage matrix and bone loss in mono-articular arthritis induced by heat-killed Mycobacterium tuberculosis

Nov 2, 2005·Inflammopharmacology·M P Seed, C R Gardner

Study on antithrombogenicity of poly[beta-(acetylsalicylyloxy)ethyl methacrylate] relative to poly(hydroxyethyl methacrylate)

Jan 1, 1991·Journal of Biomaterials Science. Polymer Edition·H SatoX D Feng

Characterization of human platelet vascular permeability-enhancing activity

Mar 1, 1972·The Journal of Clinical Investigation·R L NachmanB Ferris

Thrombin-induced increase in intracellular cyclic 3',5'-adenosine monophosphate in human platelets

Dec 1, 1972·The Journal of Clinical Investigation·M J Droller, S M Wolfe

Radioimmunoassay measurement of prostaglandins E, A, and F in human plasma

Feb 1, 1973·The Journal of Clinical Investigation·B M JaffeC W Parker

Formation of prostaglandins during the aggregation of human blood platelets

Apr 1, 1973·The Journal of Clinical Investigation·J B SmithM J Silver

Effects of prostaglandins and cholera enterotoxin on intestinal mucosal cyclic AMP accumulation. Evidence against an essential role for prostaglandins in the action of toxin

Mar 1, 1974·The Journal of Clinical Investigation·D V KimbergA Henderson

Modulation of the random migration of human platelets

Nov 1, 1974·The Journal of Clinical Investigation·F H ValoneE J Goetzl

Vitamin E. An inhibitor of the platelet release reaction

Mar 1, 1976·The Journal of Clinical Investigation·M Steiner, J Anastasi

Inhibition of platelet prostaglandin synthetase by oral aspirin

Feb 1, 1978·The Journal of Clinical Investigation·J W BurchPhilip W Majerus

Shortening of the bleeding time in rabbits by hydrocortisone caused by inhibition of prostacyclin generation by the vessel wall

May 1, 1979·The Journal of Clinical Investigation·M A BlajchmanJ F Mustard

Differential effects of two doses of aspirin on platelets-vessel wall introduction in vivo

Aug 1, 1981·The Journal of Clinical Investigation·K K WuD Matayoshi

Aspirin inhibits vascular plasminogen activator activity in vivo. Studies utilizing a new assay to quantify plasminogen activator activity

Aug 1, 1984·The Journal of Clinical Investigation·R I LevinD B Rifkin

Expression of human group II PLA2 in transgenic mice results in epidermal hyperplasia in the absence of inflammatory infiltrate

May 15, 1996·The Journal of Clinical Investigation·D S GrassM E Swanson

Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin

Mar 17, 1999·The Journal of Clinical Investigation·M L KahnS R Coughlin

Aspirin-exacerbated asthma

Jun 15, 2008·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Mathew Varghese, Richard F Lockey

Reduction of death rate due to acute myocardial infarction in subjects with cancers through systemic restoration of impaired nitric oxide

Feb 22, 2014·PloS One·Rajeshwary GhoshAsru K Sinha

The bitter barricading of prostaglandin biosynthesis pathway: understanding the molecular mechanism of selective cyclooxygenase-2 inhibition by amarogentin, a secoiridoid glycoside from Swertia chirayita

Mar 8, 2014·PloS One·Shantanu ShuklaSunil S Thorat

Diabetes mellitus: a prothrombotic state implications for outcomes after coronary revascularization

May 14, 2009·Vascular Health and Risk Management·Clarissa ColaManel Sabaté

Synthesis and pharmacological evaluation of antiinflammatory mutual amide prodrugs

Oct 2, 2013·Indian Journal of Pharmaceutical Sciences·D T MakhijaA V Chavan

Benzimidazole: an emerging scaffold for analgesic and anti-inflammatory agents

Mar 8, 2014·European Journal of Medicinal Chemistry·Monika GabaChander Mohan

Pharmacological analysis of cyclooxygenase-1 in inflammation

Oct 28, 1998·Proceedings of the National Academy of Sciences of the United States of America·C J SmithP C Isakson

Aspirin may modify tumor microenvironment via antiplatelet effect

Jun 9, 2014·Medical Hypotheses·B B SuJ Wan

Photoactive assemblies of organic compounds and biomolecules: drug-protein supramolecular systems

Mar 19, 2014·Chemical Society Reviews·Ignacio VayáMiguel A Miranda

Biologically active derivatives of fatty acids: prostaglandins, thromboxanes, and endoperoxides

Dec 1, 1977·Inflammation·F A KuehlR W Egan

Aspirin therapy in vernal conjunctivitis

Apr 1, 1983·American Journal of Ophthalmology·M B AbelsonJ H Weston

Advances in ocular therapy: noncorticosteroid anti-inflammatory agents. Fifth annual Jules Stein Lecture

Nov 1, 1974·American Journal of Ophthalmology·I H Leopold

Aspirin: pharmacology and clinical applications

Dec 24, 2011·Thrombosis·Enma V Paez EspinosaFadi T Khasawneh

Effect of aspirin and dexamethasone on intraocular pressure in primary uveitis produced by Herpes simplex virus

May 1, 1976·American Journal of Ophthalmology·M MarsettioJ O Oh

The role of dermcidin isoform 2: a two-faceted atherosclerotic risk factor for coronary artery disease and the effect of acetyl salicylic Acid on it

Mar 27, 2012·Thrombosis·Rajeshwary GhoshAsru K Sinha

The in vitro effect of pirprofen on the surface ultrastructure and function of human platelets

Apr 1, 1988·Blut·M DjaldettiI Zahavi

Current concepts for a drug-induced inhibition of formation and action of thromboxane A2

May 1, 1990·Blut·H Patscheke

Is the effect of diphenolic laxatives mediated via release of prostaglandin E?

Mar 15, 1978·Experientia·E Beubler, H Juan

Over-the-counter analgesics and antipyretics: a critical assessment

Jun 27, 2000·Clinical Therapeutics·E V HershG L Ross

Celecoxib, a selective cyclooxygenase-2 inhibitor for the treatment of rheumatoid arthritis and osteoarthritis

Oct 6, 1999·Clinical Therapeutics·M M Goldenberg

Prostaglandin production by human polymorphnuclear leucocytes during phagocytosis in vitro

Jul 15, 1977·Experientia·G ToloneC Tolone

Iron chelation as a possible mechanism for aspirin-induced malondialdehyde production by mouse liver microsomes and mitochondria

Jan 1, 1988·The Journal of Clinical Investigation·K B SchwarzS Mahanty

Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs. 1973

Feb 1, 1997·British Journal of Pharmacology·S H FerreiraJ R Vane

Anti-platelet and anti-thrombotic effects of triacetylshikimic acid in rats

Jan 16, 2002·Journal of Cardiovascular Pharmacology·Fengyang HuangEnrique Hong

Pharmacokinetics and pharmacodynamics of SM-20302, a GPIIb/IIIa receptor antagonist, in anesthetized dogs

Sep 11, 1998·Journal of Cardiovascular Pharmacology·S S RebelloB R Lucchesi

Antiplatelet and antithrombotic efficacy of SR 121787, a nonpeptide orally active GP IIb/IIIa antagonist, in rabbits: comparison with clopidogrel and aspirin

Sep 23, 1997·Journal of Cardiovascular Pharmacology·P HoffmannJ M Herbert

Antiplatelet and antithrombotic activity of L-3-n-butylphthalide in rats

May 29, 2004·Journal of Cardiovascular Pharmacology·Ying PengXiaoliang Wang

Natural salicylates: foods, functions and disease prevention

Sep 1, 2011·Food & Function·Garry G Duthie, Adrian D Wood

Perspectives in nonsteroidal anti-inflammatory agents

Jun 1, 1972·Angewandte Chemie·T Y Shen

Inhibition of the effects of rheumatoid synovial fluid cells on chondrogenesis and cartilage breakdown in vitro: possible therapeutical conclusions. A morphological--biochemical study

Jan 1, 1993·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·H Mohamed-AliH J Merker

Differential inhibition of prostaglandin synthetase and soybean lipoxygenase

Jun 1, 1972·Prostaglandins·D T Downing

Metabolism of [14C]arachidonic acid by human platelets

Feb 23, 1976·Biochimica Et Biophysica Acta·T K BillsM J Silver

Actions and interactions of bradykinin, prostaglandins, and nonsteroidal antiinflammatory agents on the eye

Mar 1, 1976·Inflammation·K E EakinsL M Greenbaum

Prostaglandins as intracellular messengers

Jun 1, 1975·Life Sciences·M J Silver, J B Smith

Inhibition of human blood platelet aggregation and the stimulation of nitric oxide synthesis by aspirin

Jan 10, 2004·Platelets·Kushal ChakrabortyAsru K Sinha

Lipoxygenase product controls the regulatory volume decrease of human platelets

Jan 1, 1991·Platelets·A Margalit, A A Livne

Antiplatelet medication in cerebrovascular disease: potential sources of controversies and future strategies

Jan 1, 1994·Platelets·H TohgiK Tamura

Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks

Jul 7, 2010·Pharmaceuticals·Inger L MeekHarald E Vonkeman

Aspirin in the treatment of acute migraine attacks

Apr 21, 2006·Expert Review of Neurotherapeutics·Hans-Christoph DienerMichael Voelker

Identifying determinants of variability to tailor aspirin therapy

Mar 9, 2013·Expert Review of Cardiovascular Therapy·Bianca RoccaFrancesca Pagliaccia

Mechanism of action of anti-inflammatory drugs

Jan 1, 1996·Scandinavian Journal of Rheumatology. Supplement·J R Vane, Regina M Botting

Pharmacokinetics and safety of a new aspirin formulation for the acute treatment of primary headaches

Sep 16, 2014·Expert Opinion on Drug Metabolism & Toxicology·Marzia LecchiPaolo Martelletti

Do prostaglandins affect cellular radiosensitivity in vitro?

Oct 1, 1984·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·B C Millar, S Jinks

Gastric mucosal damage by aspirin

Jun 1, 1975·CRC Critical Reviews in Toxicology·D J John

Novel inhibitors of cyclooxygenase-2: the sulfones and sulfonamides of 1,2-diaryl-4,5-difluorobenzene. Analysis of quantitative structure-activity relationship

Nov 24, 1998·Journal of Enzyme Inhibition·P Singh, R Kumar

1,2-Diarylimidazoles as inhibitors of cyclooxygenase-2: a quantitative structure-activity relationship study

Aug 13, 1999·Journal of Enzyme Inhibition·P Singh, R Kumar

Indomethacin inhibits bone resorption and lysosomal enzyme release from bone in organ culture

Jan 1, 1980·Scandinavian Journal of Rheumatology·U Lerner

Additive clinical effect of indomethacin suppositories during salicylate therapy in rheumatoid patients

Jan 1, 1981·Scandinavian Journal of Rheumatology·R EkstrandA Rane

Platelet aggregation in patients treated with diflunisal

Jan 1, 1980·Current Medical Research and Opinion·M L Ghosh, A Tingle

Prostaglandins, platelets, and atherosclerosis

Jan 1, 1980·CRC Critical Reviews in Biochemistry·R Gryglewski

Pulmonary effects of induced platelet aggregation. Intravascular obstruction or vasoconstriction?

Dec 1, 1971·Scandinavian Journal of Clinical and Laboratory Investigation·K RådegranP Olsson

Mechanism of action of nonsteroidal anti-inflammatory drugs

Oct 17, 1998·Cancer Investigation·Tony L YakshA B Malmberg

Acetylsalicylic acid and the balance between prostacyclin and thromboxane A2

Jan 1, 1990·Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum·L Viinikka

Acetylcholine promotes the synthesis of prostaglandin E in mouse pancreas

Aug 11, 1980·FEBS Letters·M W Banschbach, M Hokin-Neaverson

A randomized, quadruple crossover single-blind study on immediate action of chewed and unchewed low-dose acetylsalicylic acid tablets in healthy volunteers

May 6, 2011·Journal of Pharmaceutical Sciences·Yoshimichi SaiKen-ichi Miyamoto

Structural requirements for binding of nonsteroidal anti-inflammatory drugs to human serum albumin

Mar 1, 1988·Journal of Pharmaceutical Sciences·K L LiA L Kapoor

Hyporeninemic hypoaldosteronism in two patients with systemic lupus erythematosus

Jul 1, 1984·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J Kiley, P Zager

Vane's discovery of the mechanism of action of aspirin changed our understanding of its clinical pharmacology

Jul 16, 2010·Pharmacological Reports : PR·Regina M Botting

The effect of a prostaglandin synthetase inhibitor on the hormonal profile and the endometrium in women

Feb 1, 1985·American Journal of Obstetrics and Gynecology·B M LandgrenE Johannisson

Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors

Dec 15, 2015·Journal of Medicinal Chemistry·Matthew Allen SchifflerXiao-Peng Yu

Conservative Secondary Shell Substitution In Cyclooxygenase-2 Reduces Inhibition by Indomethacin Amides and Esters via Altered Enzyme Dynamics

Dec 26, 2015·Biochemistry·Mary E KonkleLawrence J Marnett

The current status of prostaglandins and the lungs

Jul 1, 1975·Chest·J O Shaw, K M Moser

Ketorolac in the era of cyclo-oxygenase-2 selective nonsteroidal anti-inflammatory drugs: a systematic review of efficacy, side effects, and regulatory issues

Apr 23, 2004·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·A Macario, A G Lipman

Nonsteroidal antiinflammatory drugs and reproduction

Nov 1, 1993·American Journal of Obstetrics and Gynecology·M Y Dawood

Cyclic 3',5'-adenosine monophosphate in human blood platelets. IV. Regulatory role of cyclic amp in platelet function

Oct 27, 1972·Annals of the New York Academy of Sciences·E W SalzmanL Levine

Eicosanoids and health

Mar 15, 1993·Annals of the New York Academy of Sciences·W E Lands

Human cutaneous inflammation induced by prostaglandin E1

Mar 1, 1973·The Journal of Pathology·J SondergaardH P Jorgensen

Platelet membrane mucopolysaccharides: some relevant observations

Oct 27, 1972·Annals of the New York Academy of Sciences·J R O'Brien

Mechanism of the irreversible inhibition of human cyclooxygenase-1 by aspirin as predicted by QM/MM calculations

Feb 7, 2013·Journal of Molecular Graphics & Modelling·L TóthI Komáromi

Blood coagulation and shock

Nov 1, 1979·Pathology, Research and Practice·T Saldeen

Inflammation. Mediators of inflammation

Jan 1, 1974·Beiträge Zur Pathologie·G B Ryan

Anti-inflammatory drugs, eicosanoids and the annexin A1/FPR2 anti-inflammatory system

Nov 30, 2011·Prostaglandins & Other Lipid Mediators·Samia YazidR J Flower

Antithrombotic activity of Z4A5, a new platelet glycoprotein IIb/IIIa receptor antagonist evaluated in a rabbit arteriovenous shunt thrombosis model

Sep 20, 2011·Thrombosis Research·Bo-Bin JingBing Wang

The cPLA2α inhibitor efipladib decreases nociceptive responses without affecting PGE2 levels in the cerebral spinal fluid

Dec 15, 2010·Neuropharmacology·Cheryl L Nickerson-NutterJames D Clark

The determination and application of fixed-dose analgesic combinations for treating multimodal pain

Mar 27, 2010·The Journal of Pain : Official Journal of the American Pain Society·Robert B RaffaRonald J Tallarida

In vitro and ex vivo inhibition of canine cyclooxygenase isoforms by robenacoxib: a comparative study

Dec 17, 2009·Research in Veterinary Science·J N KingP Lees

Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold

Jan 24, 2012·Journal of Medicinal Chemistry·Andy J LiedtkeLawrence J Marnett

Aspirin in decompression sickness

Feb 25, 2009·Thérapie·Jacques BessereauJean-Pierre Auffray

Aspirin and clopidogrel resistance

Apr 14, 2006·Mayo Clinic Proceedings·Erin D MichosHossein Ardehali

Mechanism of action of nonsteroidal anti-inflammatory drugs

Aug 10, 2000·The Veterinary Clinics of North America. Small Animal Practice·A Livingston

Topical N-acetyl-S-farnesyl-L-cysteine inhibits mouse skin inflammation, and unlike dexamethasone, its effects are restricted to the application site

Sep 21, 2007·The Journal of Investigative Dermatology·Joel S GordonMaxwell B Stock

Nonsteroidal anti-inflammatory drugs: adverse effects and their prevention

Oct 1, 2008·Seminars in Arthritis and Rheumatism·Harald E Vonkeman, Mart A F J van de Laar

Pharmacology and significance of nonsteroidal anti-inflammatory drugs in the treatment of skin diseases

Apr 1, 1987·Journal of the American Academy of Dermatology·M Greaves

Prostaglandin and non-prostaglandin mediated breeakdown of the blood-aqueous barrier

Jan 1, 1977·Experimental Eye Research·K E Eakins

Prostaglandins: their possible role in the pathogenesis of pulpal and periapical diseases, part 2

Oct 1, 1980·Journal of Endodontics·M Torabinejad, L K Bakland

Vascular permeability and other factors in the modulation of the inflammatory response

Jun 1, 1977·Journal of Endodontics·D A Willoughby

Aspirin: an update

Jul 1, 1978·Journal of Endodontics·R C BiesterfeldJ F Taintor

Intestinal mucosal damage caused by non-steroidal anti-inflammatory drugs: role of bile salts

Feb 27, 2007·Clinical Biochemistry·Michele PetruzzelliPiero Portincasa

Salicylate and enzymes

Oct 1, 1971·The Journal of Pharmacy and Pharmacology·M J Smith, P D Dawkins

Host response modulation in the management of periodontal diseases

Sep 1, 2005·Journal of Clinical Periodontology·Giovanni E Salvi, Niklaus P Lang

Pharmacodynamics and pharmacokinetics of nonsteroidal anti-inflammatory drugs in species of veterinary interest

Dec 17, 2004·Journal of Veterinary Pharmacology and Therapeutics·P LeesP L Toutain

Salicylate, an aspirin metabolite, specifically inhibits the current mediated by glycine receptors containing alpha1-subunits

Jul 15, 2009·British Journal of Pharmacology·Y-G LuL Chen

Opposite nociceptive effects of the arginine/NO/cGMP pathway stimulation in dermal and subcutaneous tissues

Apr 25, 2003·British Journal of Pharmacology·Gustavo G VivancosS H Ferreira

Anti-platelet and anti-thrombotic approaches in patients undergoing percutaneous coronary intervention

Aug 28, 2007·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Rajeev GargEli I Lev

Antagonism of thromboxane receptors by diclofenac and lumiracoxib

Oct 30, 2007·British Journal of Pharmacology·E SelgS-E Dahlén

Antiplatelet drugs

Jan 13, 2006·British Journal of Pharmacology·G V Born, Carlo Patrono

Future innovations in anti-platelet therapies

Jul 1, 2008·British Journal of Pharmacology·N E BarrettJ M Gibbins

Prostaglandins, bioassay and inflammation

Jan 13, 2006·British Journal of Pharmacology·R J Flower

Preclinical pharmacology of robenacoxib: a novel selective inhibitor of cyclooxygenase-2

Jan 24, 2009·Journal of Veterinary Pharmacology and Therapeutics·J N KingP Lees

Historical perspective and future directions in platelet research

Aug 4, 2011·Journal of Thrombosis and Haemostasis : JTH·B S Coller

Biochemical pharmacology of nonsteroidal anti-inflammatory drugs

Mar 27, 1998·Biochemical Pharmacology·K K Wu

Aspirin and pulmonary lesions in endotoxin shock

Oct 1, 1972·American Heart Journal·V S Murphy, C V Greenway

Strontium ions induce production of thromboxane B2 and secretion of 5-hydroxytryptamine in washed human platelets

Mar 15, 1981·Biochemical Pharmacology·L C BestG Russell

The relationship between concentration of prostaglandin E and rates of cell replication

Mar 15, 1974·Experimental Cell Research·D R ThomasB M Jaffe

Pathogenic Mechanisms and In Vitro Diagnosis of AERD

Jun 2, 2012·Journal of Allergy·Dirk Schäfer, Steffen Maune

Regulation of arachidonate metabolism via lipoxygenase and cyclo-oxygenase by 12-HPETE, the product of human platelet lipoxygenase

Aug 28, 1979·Biochemical and Biophysical Research Communications·M I SiegelP Cuatrecasas

Suppression of dental pain by the preoperative administration of flurbiprofen

Mar 24, 1986·The American Journal of Medicine·R A Dionne

Effect of L8027, a new potent inhibitor of prostaglandin biosynthesis, on the metabolism and response to glucagon of rat adipose tissue

Aug 1, 1974·Biochemical Pharmacology·P J Lefebvre, A S Luyckx

Comparative effect of antiplatelet therapy in retinal vein occlusion evaluated by the particle-counting method using light scattering

Nov 9, 2004·American Journal of Ophthalmology·Takami YamamotoShigeru Kinoshita

The mechanism of action of aspirin--is there anything beyond cyclo-oxygenase?

Feb 1, 1995·Medical Hypotheses·R B GhooiP S Joshi

Aggregation-induced alterations in human platelet membranes: a spin label study

Jun 30, 1980·Biochemical and Biophysical Research Communications·K OhkiY Nozawa

Aspirin-like drugs inhibit arachidonic acid metabolism via lipoxygenase and cyclo-oxygenase in rat neutrophils from carrageenan pleural exudates

Jan 29, 1980·Biochemical and Biophysical Research Communications·M I SiegelP Cuatrecasas

Sex-related difference in the effect of aspirin on prostaglandin metabolism in rat platelet and aorta

Nov 16, 1981·Biochemical and Biophysical Research Communications·M MorikawaM Tsuboi

Interactions between prostaglandin E 1 and calcium at the level of the mitochondrial membrane

Jan 1, 1973·Archives of Biochemistry and Biophysics·E Carafoli, F Crovetti

Prostaglandin dehydrogenase activity of purified rat liver 3 alpha-hydroxysteroid dehydrogenase

Oct 29, 1987·Biochemical and Biophysical Research Communications·T M Penning, R B Sharp

Inhibition of prostaglandin synthesis in man

Nov 1, 1972·Biochemical and Biophysical Research Communications·M Hamberg

Renal concentrations of prostaglandin E in acute and chronic renal ischemia

Nov 1, 1972·Biochemical and Biophysical Research Communications·B M JaffeP Needleman

Steroid hormones, anti-inflammatory steroids and prostaglandins

Aug 1, 1976·Pharmacological Research Communications·R Gryglewski

The use of urinary N-acetyl-beta-glucosaminidase in human renal toxicology. II. Elevation in human excretion after aspirin and sodium salicylate

Jun 30, 1979·Toxicology and Applied Pharmacology·T D Lockwood, H B Bosmann

The occurrence of prostaglandins and related compounds in lower organisms

Jun 1, 1995·Prostaglandins, Leukotrienes, and Essential Fatty Acids·M Lamacka, J Sajbidor

Prostaglandins, their inhibitors and cancer

Feb 1, 1996·Prostaglandins, Leukotrienes, and Essential Fatty Acids·A Lupulescu

Mechanism of inhibitory effect of some amphiphilic drugs on platelet aggregation induced by collagen, thrombin or arachidonic acid

Sep 15, 1983·Thrombosis Research·Y KanahoT Fujii

Inhibition of prostaglandin biosynthesis by 2-aryl-1,3-indandiones

May 15, 1975·Biochemical Pharmacology·G van den BergW T Nauta

Studies on the mechanism of action of 12-deoxyphorbolphenylacetate, a potent platelet aggregating tigliane ester

Oct 1, 1981·Biochemical Pharmacology·E M WilliamsonF J Evans

Differential effects of oral administrations to human volunteers of acetylsalicylic acid, sodium salicylate and indomethacin on 12-hydroxyeicosatetraenoic acid formation by stimulated platelets

Nov 1, 1988·Thrombosis Research·P MadernaG Galli

A study of the bioavailability and platelet inhibitory effects of a new enteric-coated acetylsalicylic acid preparation

Jun 15, 1984·Thrombosis Research·J G KeltonK B Nguyen

Prostaglandins, aspirin, and analgesia

May 5, 1973·Lancet

Role of prostaglandins in the pathogenesis of Bartter's syndrome

May 31, 1976·The American Journal of Medicine·M P FichmanR Rude

The pathophysiological effects of nitrogen mustard on the rabbit eye. I. The biphasic intraocular pressure response and the role of prostaglandins

Jan 1, 1980·Experimental Eye Research·C B Camras, L Z Bito

Increase of platelet prostaglandin cyclic endoperoxides in thrombosis

Jan 8, 1977·Lancet·M Lagarde, M Dechavanne

Aspirin fails to inhibit platelet aggregation in sheep

Nov 1, 1993·Thrombosis Research·H G Spanos

A study of the stimulation of human venous prostacyclin synthesis by dipyridamole

Sep 1, 1982·Thrombosis Research·C A JacksonF E Preston

Glucocorticoids and prostaglandin synthesis: we cannot see the wood for the trees

Feb 1, 1992·Prostaglandins, Leukotrienes, and Essential Fatty Acids·D Duval, M Freyss-Beguin

Inhibition of platelet aggregation by a new agent, 2,2'-dithiobis-(N-2-hydroxypropyl benzamide) (KF4939)

Jan 15, 1983·Thrombosis Research·K YamadaN Nakamizo

Differential inhibition of platelet thromboxane and lung prostacyclin production by sulphinpyrazone, acetylsalicylic acid and indomethacin by human tissues in vitro

Feb 15, 1985·Thrombosis Research·J ToivanenL Viinikka

The mechanisms of action of ticlopidine

Jan 1, 1983·Thrombosis Research. Supplement·J J Bruno

Platelet trapping in myocardial infarct in baboons: therapeutic effect of aspirin

Sep 1, 1980·The American Journal of Cardiology·W RufS A Wickline

Trends in microvascular research. The microembolism syndrome

Mar 1, 1976·Microvascular Research·T Saldeen

Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects

Feb 1, 1980·Thrombosis Research·Carlo PatronoB A Peskar

Influence of epinephrine on the aggregation response of aspirin-treated platelets

Jul 1, 1980·Prostaglandins and Medicine·G H RaoJ G White

1-arachidonyl-monoglyceride causes platelet aggregation: indirect evidence for an acylglycerol acylhydrolase involvement in the release of arachidonic acid for prostaglandin synthesis

Jun 1, 1980·Prostaglandins and Medicine·J M Gerrard, G Graff

The effect of anti-inflammatory drugs on glycosaminoglycan sulphation in pig cartilage

Mar 1, 1980·Prostaglandins and Medicine·S DekelM J Francis

Inhibition of human platelet cyclooxygenase by alpha-tocopherol

Feb 1, 1980·Prostaglandins and Medicine·M AliJ W McDonald

Interference by sulfinpyrazone and salicylate of aspirin inhibition of platelet cyclooxygenase activity

Dec 1, 1979·Prostaglandins and Medicine·M Ali, J W McDonald

Resistance of the renal biosynthesis of prostaglandin E2 to the inhibitory effect of indomethacin in the rat in vivo

Oct 1, 1990·Prostaglandins, Leukotrienes, and Essential Fatty Acids·R Hui, P Falardeau

Effect of three nonsteroidal anti-inflammatory agents on platelet function and prostaglandin synthesis in vitro

Jan 1, 1978·Thrombosis Research·B A McIntyre, R B Philp

Synthesis of prostaglandin D2 and thromboxane B2 by human platelets

Oct 1, 1977·Thrombosis Research·M AliJ W McDonald

Failure of aspirin at different doses to modify experimental thrombosis in rats

Jun 1, 1980·Thrombosis Research·I ReyersG De Gaetano

Thromboxane B2 and 6-keto-prostaglandin F1 alpha synthesis during infusion of collagen and arachidonic acid in rabbits: inhibition by aspirin and sulfinpyrazone

Jun 1, 1980·Thrombosis Research·A L CerskusJ W McDonald

In vitro platelets/endothelial cells interactions in presence of acetylsalicylic acid at various dosages

Jan 1, 1992·Thrombosis Research·M C LalanneC Doutremepuich

Interaction of albumin, arachidonic acid and prostanoids in platelets

Mar 1, 1989·Prostaglandins, Leukotrienes, and Essential Fatty Acids·A D Purdon, A K Rao

Endogenous inhibition of arachidonic acid metabolism in the endometrium of the sheep

Mar 1, 1989·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Samar Basu

Effects of repeated oral doses of fenflumizole on platelet aggregation and thromboxane formation in man ex vivo

Feb 1, 1988·Prostaglandins, Leukotrienes, and Essential Fatty Acids·M L Dahl-PuustinenT Puustinen

Platelet aggregability, thromboxane A2 and malonaldehyde formation following administration of aspirin to man

Jan 1, 1979·Thrombosis Research·A SzczeklikE Marcinkiewicz

The determination of MDA as a simple technique for the control of the therapy with aspirin

Feb 1, 1979·Thrombosis Research·M T SantosM A Fernandez

The role of non-steroidal anti-inflammatory drugs in the management of periodontal disease

Dec 1, 1988·Journal of Dentistry·P A Heasman

Aspirin, prostaglandin E1 and Quin-2 AM-induced platelet dysfunction: restoration of function by noradrenalin

Feb 1, 1990·Prostaglandins, Leukotrienes, and Essential Fatty Acids·G H Rao, J G White

Thromboxane production and platelet aggregation in diabetic subjects with clinical complications

Jul 1, 1980·Thrombosis Research·A ButkusO P Schumacher

Further evidence against the validity of using an ADP-removing enzyme system (CP/CPK) for demonstrating the role of secreted ADP in platelet activation

Apr 1, 1983·Thrombosis Research·B Nunn, P D Chamberlain

Beneficial effects of prostacyclin in a rabbit endotoxin shock model

Aug 15, 1988·Thrombosis Research·H DitterE Lohmann

Prolongation of bleeding time by aspirin: a dual mechanism?

Jun 15, 1988·Thrombosis Research·G De Gaetano, C Cerletti

Effect of acetylsalicylic acid on platelet aggregation and thromboxane B2 production in flowing aortic blood in the rat studied with a filter loop technique

Aug 1, 1982·Thrombosis Research·J F MartinE Leach

Inhibition of platelet activation by prostacyclin: possible consequences in coagulation and anticoagulation

Jan 1, 1981·Thrombosis Research·S BuntingS Moncada

The effect of inhibition of prostaglandin synthesis on microvascular haemostasis and macromolecular leakage

Mar 1, 1976·Thrombosis Research·K E ArforsE Svensjö

Low dose aspirin, platelet function and prostaglandin synthesis: influence of epinephrine and alpha adrenergic blockade

May 1, 1981·Prostaglandins and Medicine·G H RaoJ G White

Platelet aggregation independent of ADP release or prostaglandin synthesis in patients with hermansky-Pudlak syndrome

Apr 1, 1981·Prostaglandins and Medicine·G H RaoJ G White

A study of intravascular platelet aggregation by continuous platelet counting

Aug 1, 1981·Thrombosis Research·G M Smith, G G Duncan

In vitro bleeding test--a simple method for the detection of aspirin effects on platelet function

Dec 1, 1989·Thrombosis Research·V KretschmerG Dietrich

Reversible and irreversible inhibition of platelet cyclooxygenase and serotonin release by nonsteroidal antinflammatory drugs

Dec 1, 1978·Thrombosis Research·M Ali, J W McDonald

ADP-induced second wave aggregation in platelet rich plasma from hypercholesterolemic rabbits

Dec 15, 1991·Thrombosis Research·A WeberK Schrör

The relationships between cyclic AMP, calcium and prostaglandins as second messengers

Nov 1, 1977·Medical Hypotheses·D F HorrobinR O Morgan

Present concepts on the mechanisms of platelet aggregation

Feb 15, 1981·Biochemical Pharmacology·B B VargaftigJ Benveniste

Bone pain in metastatic cancer of prostate

Feb 1, 1979·Urology·J J Pollen, J D Schmidt

Nasal packing with porcine fatty tissue for epistaxis complicated by qualitative platelet disorders

Jan 1, 1985·The Journal of Emergency Medicine·M E Carr, D A Gabriel

Current recommendations in prevention of thrombosis in surgery

Dec 1, 1987·Blood Reviews·V V Kakkar

Salicylate reverses in vitro aspirin inhibition of rat platelet and vascular prostaglandin generation

Apr 15, 1980·Biochemical Pharmacology·J MerinoG De Gaetano

Prostaglandins and cyclic nucleotides in Moloney sarcoma tumors

Jan 25, 1974·Prostaglandins·J L Humes, H R Strausser

Evidence for a direct inhibitory effect of glucocorticoids on the activity of phospholipase A2 as a further possible mechanism of some actions of steroidal anti-inflammatory drugs

Sep 1, 1980·Pharmacological Research Communications·P MentzW Förster

Basal level of human platelet prostaglandins: PGE1 is more elevated than PGE2

May 1, 1979·Prostaglandins·M LagardeJ Durand

Aspirin and indomethacin abolish thyrotropin-induced increase in thyroid cell prostaglandins

Nov 1, 1972·Prostaglandins·G Burke

The influence of psychotropic drugs on prostaglandin biosynthesis

Jan 10, 1974·Prostaglandins·R E Lee

Inhibition of intestinal tone, motility and prostaglandin biosynthesis by 5,8,11,14-eicosatetraynoic acid (TYA)

Feb 25, 1974·Prostaglandins·A L WillisP W Ramwell

Use of lysed human platelets to study prostaglandin E2 production

Feb 25, 1974·Prostaglandins·N W Schoene, J M Iacono

A rapid spectrophotometric assay for prostaglandin synthetase: application to the study of non-steroidal antiinflammatory agents

Sep 1, 1972·Prostaglandins·C Takeguchi, C J Sih

The use of non-prescription analgesics in an older population

Nov 1, 1982·Journal of the American Geriatrics Society·G C Cupit

Teratogenic effects on the CD-1 mouse embryo exposed to concurrent doses of ethanol and aspirin

Dec 1, 1986·Teratology·J F Guy, M E Sucheston

Inhibition of prostaglandin E2 release by salicylates, benzoates and phenols: a quantitative structure-activity study

Nov 1, 1983·The Journal of Pharmacy and Pharmacology·J Habicht, K Brune

Indomethacin and ascorbate inhibit desmoid tumors

Jan 1, 1980·Journal of Surgical Oncology·W R Waddell, R E Gerner

Effects of dazoxiben, an inhibitor of thromboxane synthetase, on forearm vasoconstriction in response to cold stimulation, and on human blood vessel prostacyclin production

Jan 1, 1983·British Journal of Clinical Pharmacology·A J CowleyS P Hanley

Differential effect of aspirin on thromboxane and prostaglandin biosynthesis in man

Nov 1, 1989·British Journal of Clinical Pharmacology·J M RitterS E Barrow

The synovial prostaglandin system in chronic inflammatory arthritis: differential effects of steroidal and nonsteroidal anti-inflammatory drugs

Aug 1, 1981·British Journal of Pharmacology·S BombardieriF Pugliese

Effect of some non-steroidal anti-inflammatory drugs on ouabain-induced arrhythmias in guinea-pigs

Apr 1, 1988·British Journal of Pharmacology·R M Tripathi, R Kaushal

Inability of prostaglandin synthesis inhibitors to affect adipose tissue lipolysis

Nov 1, 1973·Prostaglandins·C Dalton, H R Hope

The effects of prostaglandins E2, F2 alpha, prostacyclin, flurbiprofen and aspirin on arrhythmias resulting from coronary artery ligation in anaesthetized rats

Sep 1, 1981·British Journal of Pharmacology·S J Coker, J R Parratt

Effects of 6-[p-(4-phenylacetylpiperazin-1-yl)phenyl]-4,5-dihydro-3(2H)pyridazinone (CCI 17810) and aspirin on platelet aggregation and adhesiveness

Apr 1, 1981·British Journal of Pharmacology·E M GriffettE G Tomich

Recovery of prostacyclin synthesis by rabbit aortic endothelium and other tissues after inhibition by aspirin

May 1, 1987·British Journal of Pharmacology·C E Frazer, J M Ritter

Template bleeding time and thromboxane generation in the horse: effects of three non-steroidal anti-inflammatory drugs

Jul 1, 1985·Equine Veterinary Journal·K J KoppP Brooks

Influence of prostacyclin and indomethacin on castor oil-induced gastrointestinal effects in rats

Mar 1, 1983·The Journal of Pharmacy and Pharmacology·P Vischer, J Casals-Stenzel

Effect of alpha-Tocopherol on endotoxicosis

Jan 1, 1981·Microbiology and Immunology·O SakaguchiH Abe

Platelet dysfunction in myeloproliferative syndromes

Jan 1, 1981·American Journal of Hematology·K PhadkeW R Pitney

The mechanisms of action of nonsteroidal antiinflammatory drugs

Jan 1, 1989·Arthritis and Rheumatism·S B Abramson, G Weissmann

Modulation of pokeweed mitogen-induced human B-cell differentiation by aggregated IgG

Aug 1, 1984·Scandinavian Journal of Immunology· Lê Thi Bich-Thuy, J P Revillard

The effects of the combined administration of beta-adrenoceptor antagonists and non-steroidal anti-inflammatory drugs on ligation-induced arrhythmias in rats

Jun 1, 1985·British Journal of Pharmacology·O Fagbemi

Biochemistry of the prostaglandins

Dec 1, 1992·Baillière's Clinical Obstetrics and Gynaecology·M D Mitchell

The acute inflammatory process, arachidonic acid metabolism and the mode of action of anti-inflammatory drugs

May 1, 1984·Equine Veterinary Journal·A J Higgins, P Lees

Dose-dependent inhibition of phosphoinositide metabolism in human platelets by aspirin in vitro and in vivo

Oct 1, 1986·British Journal of Clinical Pharmacology·P P GodfreyD G Grahame-Smith

Peripheral analgesia: mechanism of the analgesic action of aspirin-like drugs and opiate-antagonists

Oct 1, 1980·British Journal of Clinical Pharmacology·S H Ferreira

Arachidonic acid metabolism, pain and hyperalgesia: the mode of action of non-steroid mild analgesics

Oct 1, 1980·British Journal of Clinical Pharmacology·G A Higgs

Potential therapeutic applications of aspirin and other cyclo-oxygenase inhibitors

Oct 1, 1980·British Journal of Clinical Pharmacology·A E Farah, F Rosenberg

Effect of nabumetone (BRL 14777), a new anti-inflammatory drug, on human platelet reactivity ex vivo: comparison with naproxen

Sep 1, 1982·The Journal of Pharmacy and Pharmacology·B Nunn, P D Chamberlain

Interaction between salicylate and two loop diuretics

Dec 1, 1979·British Journal of Clinical Pharmacology·H Valette, E Apoil

Lack of platelet effect with the aspirin analog, salsalate

Nov 1, 1980·Arthritis and Rheumatism·D Estes, K Kaplan

Effects of salicylic and acetylsalicylic acid alone and in combination on platelet aggregation and prostanoid synthesis in man

Mar 1, 1986·British Journal of Clinical Pharmacology·B RosenkranzJ C Frölich

Prostaglandins, hydroxy fatty acids, leukotrienes and inflammation of the skin

Jul 1, 1982·Clinical and Experimental Dermatology·R D Camp

Platelet-coagulant protein interactions in contact activation

Jan 1, 1981·Annals of the New York Academy of Sciences·P N Walsh, J H Griffin

Metastasis in the androgen-insensitive Nb rat prostatic carcinoma system

Apr 1, 1985·Journal of Surgical Oncology·J R Drago, J S Lombard

Suppression of postoperative pain by preoperative administration of ibuprofen in comparison to placebo, acetaminophen, and acetaminophen plus codeine

Jan 1, 1983·Journal of Clinical Pharmacology·R A DionneB Buckingham

Peripheral antialgesics: a review

Nov 1, 1983·Journal of Clinical Pharmacology·R J CapetolaJ L McGuire

Effect of various doses of acetylsalicylic acid in combination with dipyridamole on the balance between prostacyclin and thromboxane in human serum

Feb 1, 1981·British Journal of Pharmacology·L Viinikka, O Ylikorkala

Drugs and the periodontium

Jan 1, 1988·Journal of Clinical Periodontology·R A Seymour, P A Heasman

The osteoclast and periodontitis

Apr 1, 1986·Journal of Clinical Periodontology·J D Sterrett

Prostaglandins and lymphokines in arthritis

Nov 25, 1974·Prostaglandins·J Morley

Nobel lecture, 8th December 1982. Adventures and excursions in bioassay: the stepping stones to prostacyclin

Aug 1, 1983·British Journal of Pharmacology·J R Vane

Epinephrine potentiation of arachidonate-induced aggregation of cyclooxygenase-deficient platelets

Dec 1, 1981·American Journal of Hematology·G H Rao, J G White

Cyclic AMP regulation of prostaglandin biosynthesis in fat cells

May 10, 1974·Prostaglandins·C Dalton, W C Hope

Effects of indomethacin on Moloney sarcoma virus-induced tumors

Jun 25, 1974·Prostaglandins·J L HumesH R Strausser

Inhibition of indomethacin-induced gastric ulceration in the rat by perorally-administered synthetic and natural prostaglandin analogues

Jul 10, 1974·Prostaglandins·W Lippmann

Effect of synthetic gonadotrophin-releasing hormone (Gn-RH) on ovulation blockade by aspirin and indomethacin

Apr 1, 1972·Prostaglandins·H R BehrmanR O Greep

Prostaglandins in health and disease: an overview

Aug 5, 2006·Seminars in Arthritis and Rheumatism·Stephen B Miller

Contributions of cyclooxygenase-2 to neuroplasticity and neuropathology of the central nervous system

Jun 6, 2006·Pharmacology & Therapeutics·Sandra J HewettJames A Hewett

Mechanism of action of non-steroidal anti-rheumatic drugs

Aug 1, 1988·Baillière's Clinical Rheumatology·M Forrest, P Brooks

Selective cyclooxygenase-2 inhibitors

Jun 5, 1999·Rheumatic Diseases Clinics of North America·B D Golden, S B Abramson

The mode of action of aspirin and similar compounds

Dec 1, 1976·The Journal of Allergy and Clinical Immunology·J R Vane

Prostacyclin-dependent differences in TXA2 formation by platelets from normal and atherosclerotic rabbits

Jun 1, 1979·Atherosclerosis·A Dembińska-KièćP S Schönhöfer

Microvascular ultrastructure in thermal injury: a reconsideration of the role of mediators

Jan 1, 1973·Microvascular Research·S M SheaJ F Burke

Fatty acids and the initial events of endothelial damage seen by scanning and transmission electron microscopy

Aug 1, 1978·Atherosclerosis·A W SedarJ B Smith

The role of aspirin-triggered lipoxins in the mechanism of action of aspirin

Jun 28, 2005·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Derek W Gilroy

Mechanism of action of analgesics used to treat osteoarthritis pain

Nov 8, 2003·Rheumatic Diseases Clinics of North America·Robert B Raffa

Aspirin inhibits phospholipase C

Aug 29, 1986·Biochemical and Biophysical Research Communications·J S BomalaskiM A Clark

Variability in the responsiveness to low-dose aspirin: pharmacological and disease-related mechanisms

Jan 31, 2012·Thrombosis·Bianca Rocca, Giovanna Petrucci

Inhibition of prostaglandin biosynthesis

May 15, 1974·Biochemical Pharmacology·R J Flower, J R Vane

Effects of cyclooxygenase products of arachidonic acid metabolism on cutaneous nociceptive threshold in the rat

Dec 24, 1990·Brain Research·Y O Taiwo, J D Levine

Why do some beta adrenergic agonists inhibit generation of thromboxane A2 in incubates of platelets with arachidonic acid?

Jan 1, 1978·Biochemical Pharmacology·M Chignard, B B Vargaftig

Aspirin therapy: optimized platelet inhibition with different loading and maintenance doses

Sep 1, 1995·American Heart Journal·M BuerkeH Darius

Effect of arachidonic acid on some inhibitors of the human platelet release reaction

Jan 1, 1978·Biochemical Pharmacology·R G LeonardiA Parts

Prostaglandin production by mouse fibrosarcoma cells in culture: inhibition by indomethacin and aspirin

May 26, 1972·Biochemical and Biophysical Research Communications·L LevineA H Tashjian

A brief review of 50 years of perioperative thrombosis and hemostasis management

Nov 13, 2013·Seminars in Hematology·Serena Valsami, Lars M Asmis

Irreversible platelet aggregation does not depend on lipoxygenase metabolites

Aug 30, 1985·Biochemical and Biophysical Research Communications·G H RaoJ G White

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Jan 31, 1972·Biochemical and Biophysical Research Communications·R V Tomlinson, H J Ringold

Platelet thromboxane A2/prostaglandin H2 receptors in human volunteers on low doses of aspirin

Oct 1, 1990·Biochemical Pharmacology·R H Covatto, S Niewiarowski

The biologic background to some therapeutic uses of aspirin

Jun 14, 1983·The American Journal of Medicine·G V BornNicola Begent

Aspirin, prostaglandins, and peripheral gangrene

Jun 14, 1983·The American Journal of Medicine·F E Preston

Effects of acetylsalicylic acid and dietary intervention on primary hemostasis

Jun 14, 1983·The American Journal of Medicine·M Thorngren, A Gustafson

Influence of aspirin on platelets and the bleeding time

Jun 14, 1983·The American Journal of Medicine·C H Mielke

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Dec 15, 1973·Biochemical Pharmacology·J F Mustard, M A Packham

Sulfinpyrazone and aspirin increase epicardial coronary collateral flow in dogs

Apr 1, 1981·The American Journal of Cardiology·N DavenportS E Epstein

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Mar 1, 1975·Biochemical Pharmacology·E C KuW D Cash

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Dec 1, 1978·American Heart Journal·S Wessler, S N Gitel

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Sep 23, 2003·Journal of Chemical Information and Computer Sciences·Shashidhar N Rao, Thomas P Stockfisch

Interference of some thiol derivatives with the pharmacological effects of arachidonic acid and slow reacting substance C and with the release of rabbit aorta contracting substances

Apr 1, 1972·European Journal of Pharmacology·B B Vargaftig, N Dao Hai

Synthesis of Novel Substituted Thiourea and Benzimidazole Derivatives Containing a Pyrazolone Ring as Anti-Inflammatory Agents

Dec 20, 2015·Chemical Biology & Drug Design·Ashraf A MoneerHala B El-Nassan

Inflammation in venous thromboembolism: Cause or consequence?

Aug 9, 2015·International Immunopharmacology·Amene SaghazadehNima Rezaei

Syntheses and characterization of nimesulide derivatives for dual enzyme inhibitors of both cyclooxygenase-1/2 and 5-lipoxygenase

Feb 26, 2011·Bioorganic & Medicinal Chemistry·Yue LiZhi-Shu Huang

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Mar 18, 2015·Lancet·Jessica L Mega, Tabassome Simon

Structure activity relationship among 6-substituted-2-naphthylacetic acids. A new series of nonsteroidal anti-inflammatory agents

Jan 1, 1973·Scandinavian Journal of Rheumatology. Supplement·J H FriedA Tomolonis

Effects of indomethacin on the transcapillary leakage of macromolecules and the efflux of prostaglandins in the paw lymph following experimental scalding injury

Jul 1, 1973·Upsala Journal of Medical Sciences·G Arturson, C E Jonsson

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Aug 1, 1983·Bioscience Reports·J R Vane

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Sep 1, 2005·Bioscience Reports·J R Vane

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Feb 27, 2014·Biochimica Et Biophysica Acta·Andreas E KremerRonald P J Oude Elferink

Prostanoids and NSAIDs in cardiovascular biology and disease

May 29, 2015·Current Atherosclerosis Reports·Babettte B Weksler

Suppression of postoperative pain by the combination of a nonsteroidal anti-inflammatory drug, flurbiprofen, and a long-acting local anesthetic, etidocaine

Apr 1, 1984·The Journal of the American Dental Association·R A DionneR Dubner

A potential role of PUFAs and COXIBs in cancer chemoprevention

Apr 25, 2015·Prostaglandins & Other Lipid Mediators·Marianela Vara-MesslerMalvina Hoxha

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Dec 24, 2013·Advances in Biological Regulation·Philip W Majerus

Endogenous opioid peptide responses to opioid and anti-inflammatory medications following eccentric exercise-induced muscle damage

Oct 6, 2009·Peptides·William J KraemerCarl M Maresh

Effect of Hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino Wistar rats

Jan 21, 2012·Thrombosis Research·Abdullah S ShatoorNadia El-Menshawy

Anti-inflammatory effects of OBA-09, a salicylic acid/pyruvate ester, in the postischemic brain

Jul 16, 2013·Brain Research·Hye-Kyung LeeJa-Kyeong Lee

Systematic review of randomized controlled trials of aspirin and oral anticoagulants in the prevention of graft occlusion and ischemic events after infrainguinal bypass surgery

Oct 8, 1999·Journal of Vascular Surgery·M J TangelderB C Eikelboom

Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration

Nov 3, 1995·Cell·R LangenbachO Smithies

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Feb 13, 2013·Proceedings of the National Academy of Sciences of the United States of America·Dionéia AraldiCarlos Amilcar Parada

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Jan 1, 1988·The Veterinary Clinics of North America. Small Animal Practice·J L Catalfamo, W J Dodds

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May 1, 1982·Pain·Tony L Yaksh, Donna L Hammond

Acetylsalicylic acid activates antinociceptive brain-stem reflex activity in headache patients and in healthy subjects

Feb 1, 1992·Pain·Hartmut GöbelLars Weigle

Effects of acetaminophen and antipyrine on non-inflammatory pain and EEG activity

Aug 1, 1992·Pain·B BrommE Scharein

Inhibition of interleukin-1beta-induced COX-2 and EP3 gene expression by sodium salicylate enhances pancreatic islet beta-cell function

May 29, 2002·Diabetes·Phuong Oanh T TranR Paul Robertson

Comparative pharmaceutical study on colon targeted micro-particles of celecoxib: in-vitro-in-vivo evaluation

Apr 19, 2016·Drug Delivery·Lamyaa BazanSabry Sayed Badawy

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Jan 1, 1975·Biochemical Pharmacology·B B Fredholm, P Hedqvist

Indomethacin and glucocorticoid metabolism in rat liver cytosol

Dec 1, 1986·Biochemical Pharmacology·T M Penning

Time-dependent inhibition of platelet aggregation by dopamine and 3-methoxytyramine. Important roles of their metabolites

Feb 1, 1984·Biochemical Pharmacology·H KodairaT Nakajima

Inhibition of the A-23187-stimulated leukotriene and prostaglandin biosynthesis of rat basophil leukemia (RBL-1) cells by nonsteroidal anti-inflammatory drugs, antioxidants, and calcium channel blockers

Oct 15, 1983·Biochemical Pharmacology·L Levine

Inflammation targeted Gd(3+)-based MRI contrast agents imaging tumor and rheumatoid arthritis models

May 27, 2014·Bioconjugate Chemistry·Arthur Ho-Hon LeungWing-Tak Wong

Phosphatidylcholine attenuates aggregation of nonsteroidal anti-inflammatory drugs with bile acid

Sep 27, 2013·Biochemistry·Priyanka Prakash, Alemayehu A Gorfe

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The use of aspirin in ischemic heart disease

Jul 16, 1992·The New England Journal of Medicine·J E WillardL D Hillis

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Sep 15, 1988·The New England Journal of Medicine·J A OatesL J Roberts

Aspirin, the ageless remedy?

Oct 31, 1991·The New England Journal of Medicine·J A Mills

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Nov 1, 1977·New Zealand Veterinary Journal·E W JonesL Bush

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Aug 1, 1979·Journal of Neurosurgery·R P WhiteJ T Robertson

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Cholera toxin-fat cell interaction and the mechanism of activation of the lipolytic response

Aug 28, 1973·Biochemistry·P Cuatrecasas

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Dec 1, 1974·The British Journal of Surgery·E D Cooke, M F Picher

Interpreting the clinical significance of the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2

Sep 29, 1999·Rheumatology·P BrooksH Zeidler

Non-steroidal anti-inflammatory drugs: back to the future

Sep 29, 1999·Rheumatology·R J Flower

New insights into the anti-inflammatory actions of aspirin-induction of nitric oxide through the generation of epi-lipoxins

Jun 18, 2005·Memórias do Instituto Oswaldo Cruz·Derek W Gilroy

Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol)

Dec 15, 1972·Nature·R J Flower, J R Vane

Prevention of cholera-induced intestinal secretion in the cat by aspirin

Aug 4, 1972·Nature·A D Finck, R L Katz

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Jul 2, 1971·Nature·H O Collier

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Nov 23, 1973·Nature·T J Williams, J Morley

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Nov 23, 1973·Nature·S MoncadaJ R Vane

Aspirin, indomethacin, catecholamine and prostaglandin interactions on rat arterioles and rabbit hearts

Aug 2, 1974·Nature·D F HorrobinP A Davies

Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation

Mar 29, 1979·Nature·R J Flower, G J Blackwell

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Sep 11, 1980·Nature·G J BlackwellP Persico

Role of prostaglandin-mediated vasodilatation in inflammation

Dec 8, 1977·Nature·T J Williams, M J Peck

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Jun 16, 1977·Nature·R GryglewskiK Bieron

Aspirin causes short-lived inhibition of bradykinin-stimulated prostacyclin production in man

Nov 14, 1985·Nature·D J HeaveyJ M Ritter

Synthetic diets in renal failure

Aug 14, 1971·Lancet·B E ClaytonI Smith

Inhibition of prostaglandin release and the control of threatened abortion

Aug 14, 1971·Lancet·A TothillJ Draper

Aspirin and indomethacin prolong parturition in rats: evidence that prostaglandins contribute to expulsion of fetus

Nov 3, 1972·Nature·J W Aiken

Delay of parturition in the rat by anti-inflammatory agents which inhibit the biosynthesis of prostaglandins

Nov 3, 1972·Nature·R ChesterA L Walpole

Cholera enterotoxin: failure of anti-inflammatory agents to prevent cyclic AMP accumulation

Feb 9, 1973·Nature·H R Bourne

Detection of thromboxane B2 in peripheral blood of patients with Prinzmetal's angina

Apr 1, 1979·Prostaglandins and Medicine·R I LewyL Wiener

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Oct 25, 1974·Nature·J J BrunoM J Droller

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Nov 22, 2007·Journal of Cardiovascular Pharmacology·Steven J Feinmark

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Jul 10, 2001·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·G SyrbeT Herzog

Acetylsalicylic acid treatment improves differentiation and immunomodulation of SHED

Nov 15, 2014·Journal of Dental Research·Y LiuS Shi

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Oct 4, 2003·Nature Reviews. Drug Discovery·Shaun P Jackson, Simone M Schoenwaelder

Eicosanoids in platelets and the effect of their modulation by aspirin in the cardiovascular system (and beyond)

Mar 8, 2018·British Journal of Pharmacology·Marilena CrescenteTimothy D Warner

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Mar 1, 1983·Pharmacotherapy·Richard O Davies

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Sep 24, 2017·Physiological Genomics·Anna Alexanian, Andrey Sorokin

Anti-inflammatory, analgesic and anti-pyretic effects of d-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid (M-5011), a new non-steroidal anti-inflammatory drug, in rats and guinea pigs

Mar 28, 1998·Japanese Journal of Pharmacology·H KidoT Naruse

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Mar 4, 2003·Nature Reviews. Drug Discovery·R J Flower

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Aug 22, 2018·The Analyst·Cuiping ZhangHongxiu Yu

The platelet aggregometer and beyond: Gustav Born at the Royal College of Surgeons

Sep 12, 2018·Platelets·Anne AthertonY S Bakhle

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Sep 1, 1976·Circulation·Philip W Majerus

Platelet function, thromboxane formation and blood pressure control during supplementation of the Western diet with cod liver oil

Mar 1, 1983·Circulation·R LorenzP C Weber

Combined use of aspirin and heparin inhibits in vivo acute carotid thrombosis

Jun 1, 1993·Stroke; a Journal of Cerebral Circulation·Z S HuangC Y Wang

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Jan 11, 2000·Circulation Research·A M Lefer

Cumulative inhibitory effect of low-dose aspirin on vascular prostacyclin and platelet thromboxane production in patients with atherosclerosis

Feb 1, 1985·Circulation·B B WekslerW A Gay

Chimeric 7E3 prevents carotid artery thrombosis in cynomolgus monkeys

Jun 1, 1994·Stroke; a Journal of Cerebral Circulation·W E RoteB R Lucchesi

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Sep 1, 1978·Stroke; a Journal of Cerebral Circulation·M Linder, J F Alksne

Experimental study on the genesis of cerebral vasospasm

Jan 1, 1975·Stroke; a Journal of Cerebral Circulation·R P WhiteJ T Robertson

Differences in the occurrence of carotid transient ischemic attacks associated with antiplatelet aggregation therapy

Sep 1, 1973·Stroke; a Journal of Cerebral Circulation·M L DykenF H Jones

Aspirin treatment reduces platelet resistance to deformation

Jul 1, 1987·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·S M BurrisJ G White

Antithrombotic therapy in coronary artery disease

Mar 1, 1985·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·V Bertelé, E W Salzman

Ibuprofen protects platelet cyclooxygenase from irreversible inhibition by aspirin

Jul 1, 1983·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·G H RaoJ G White

Isoproterenol treatment of visual symptoms in migraine

May 1, 1979·Stroke; a Journal of Cerebral Circulation·M J KupersmithN E Chase

Synthesis of prostaglandins and thromboxane B2 by cerebral arteries

May 1, 1979·Stroke; a Journal of Cerebral Circulation·A A HagenJ T Robertson

Intravenous aspirin causes a paradoxical attenuation of cerebrovascular thrombolysis

Jun 1, 1995·Stroke; a Journal of Cerebral Circulation·G R ThomasW F Bennett

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May 1, 1977·Stroke; a Journal of Cerebral Circulation·W S FieldsR J Hardy

Pleocytosis and elevation of prostaglandins F2a and E2 in cerebrospinal fluid following intracisternal injection of thrombin

Mar 1, 1977·Stroke; a Journal of Cerebral Circulation·A A HagenJ T Robertson

XIV. Cerebral ischemia: the role of thrombosis and of antithrombotic therapy. Study group on antithrombotic therapy

Jan 1, 1977·Stroke; a Journal of Cerebral Circulation·E GentonJ C Hoak

Pharmacology of platelet inhibition in humans: implications of the salicylate-aspirin interaction

Dec 1, 1985·Circulation·G De GaetanoR Latini

Aspirin enhances the benefits of late reperfusion on infarct shape. A possible mechanism of the beneficial effects of aspirin on survival after acute myocardial infarction

Jun 1, 1995·Circulation·I A AlhaddadE J Brown

SC-54684A: an orally active inhibitor of platelet aggregation

Jan 15, 1995·Circulation·N S NicholsonK Broschat

Extended inhibition of platelet aggregation with the orally active platelet inhibitor SC-54684A

Jan 15, 1995·Circulation·J A SzalonyL P Feigen

Influence of inhibitors of prostaglandin synthesis on renal vascular resistance and on renal vascular responses to vasopressor and vasodilator agents in the cat

Apr 1, 1977·Circulation Research·B M ChapnickP J Kadowitz

The protective dose of the potent GPIIb/IIIa antagonist SC-54701A is reduced when used in combination with aspirin and heparin in a canine model of coronary artery thrombosis

Jan 1, 1996·Circulation·L G FrederickL P Feigen

Effect of aspirin and ticlopidine on platelet deposition in carotid atherosclerosis: assessment by indium-111 platelet scintigraphy

Nov 1, 1986·Stroke; a Journal of Cerebral Circulation·Y IsakaM Kusunoki

Effects of acetylsalicylic acid on the ductus arteriosus and circulation in fetal lambs in utero

May 1, 1976·Circulation Research·M A Heymann, A M Rudolph

Prostaglandin-induced preservation of the ischemic myocardium

Feb 1, 1978·Circulation Research·M L Ogletree, A M Lefer

Relative effects of aspirin on platelet aggregation and prostaglandin-mediated coronary vasodilatation in the dog

Dec 1, 1980·Circulation·N L CapurroS E Epstein

Failure of thromboxane A2 blockade to prevent attacks of vasospastic angina

Oct 1, 1982·Circulation·S ChierchiaA Maseri

Effects of hydrocortisone and aminophylline on the aggregation of equine platelets in vitro

Sep 8, 2011·Journal of Veterinary Science·Stefania CasellaGiuseppe Piccione

Why are some individuals resistant to the cardioprotective effects of aspirin? Could it be thromboxane A2?

Apr 10, 2002·Circulation·Marc K Halushka, Perry V Halushka

Cholera and prostaglandins

Jun 25, 1971·Nature·A Bennett