PMID: 9419361Feb 21, 1998Paper

Assaying genome-wide recombination and centromere functions with Arabidopsis tetrads

Proceedings of the National Academy of Sciences of the United States of America
G P CopenhaverD Preuss

Abstract

During meiosis, crossover events generate new allelic combinations, yet the abundance of these genetic exchanges in individual cells has not been measured previously on a genomic level. To perform a genome-wide analysis of recombination, we monitored the assortment of genetic markers in meiotic tetrads from Arabidopsis. By determining the number and distribution of crossovers in individual meiotic cells, we demonstrated (i) surprisingly precise regulation of crossover number in each meiosis, (ii) considerably reduced recombination along chromosomes carrying ribosomal DNA arrays, and (iii) an inversely proportional relationship between recombination frequencies and chromosome size. This use of tetrad analysis also achieved precise mapping of all five Arabidopsis centromeres, localizing centromere functions in the intact chromosomes of a higher eukaryote.

References

Jan 1, 1976·Annual Review of Genetics·B S BakerL Sandler
Apr 10, 1992·Science·D B KabackJ W Mahon
Nov 1, 1991·The Plant Journal : for Cell and Molecular Biology·I HwangB Lemieux
Feb 1, 1991·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·J B Rattner
Jan 1, 1989·Genome Génome / Conseil National De Recherches Canada·W C Earnshaw, C A Cooke
Sep 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·C ChangE M Meyerowitz
Jun 1, 1974·Genetics·G R Fink, C A Styles
Nov 7, 1995·Proceedings of the National Academy of Sciences of the United States of America·T L Orr-Weaver
Jun 1, 1994·Current Opinion in Genetics & Development·P O Brown
Aug 1, 1993·The Plant Journal : for Cell and Molecular Biology·A Konieczny, F M Ausubel
Feb 1, 1994·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·K W Wolf
Jan 1, 1996·Genome Research·E A ZachgoH M Goodman
Dec 1, 1995·Current Opinion in Genetics & Development·C E Sunkel, P A Coelho
Oct 1, 1996·The Plant Journal : for Cell and Molecular Biology·Y G LiuR F Whittier
Nov 1, 1996·The Plant Journal : for Cell and Molecular Biology·T I SamoylovaS Miséra
Apr 1, 1997·Trends in Genetics : TIG·D Kipling, P E Warburton

❮ Previous
Next ❯

Citations

Sep 1, 2004·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Anna Westerbergh, John Doebley
Nov 19, 2004·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Haiyuan YangGuangcun He
Dec 13, 2006·Journal of Molecular Evolution·Akira Kawabe, Deborah Charlesworth
Dec 20, 2005·Molecular Genetics and Genomics : MGG·Wenxiang GaoDavid M Stelly
Jun 7, 2008·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Nicolas PouillyEric Jenczewski
Apr 7, 2000·Journal of Biotechnology·R WambuttM Rose
Jun 4, 1999·Trends in Genetics : TIG·M Bevan, G Murphy
Nov 15, 2003·Molecular Phylogenetics and Evolution·Eric H Roalson, Andrew G McCubbin
Mar 6, 1999·Current Opinion in Plant Biology·E J Richards, R K Dawe
Jun 11, 1999·The Plant Journal : for Cell and Molecular Biology·P LaufsJ Traas
Sep 21, 2000·The Plant Journal : for Cell and Molecular Biology·H A KoshinskyD W Ow
Mar 1, 2012·Proceedings of the National Academy of Sciences of the United States of America·Danelle K SeymourJulin N Maloof
Feb 7, 2001·The EMBO Journal·M GrelonG Pelletier
May 26, 2012·Genome Biology and Evolution·Eugénie PessiaGabriel A B Marais
Nov 29, 2002·Journal of Experimental Botany·M J WheelerF C H Franklin
Nov 29, 2002·Journal of Experimental Botany·Yan WangTeh-Hui Kao
Jun 26, 2010·Journal of Experimental Botany·C Jill HarrisonIan R Henderson
Nov 4, 2011·Journal of Experimental Botany·E LópezJ L Santos
Jan 19, 2002·Genes & Development·Trevor L StokesEric J Richards
Aug 19, 2007·PLoS Genetics·Luke E BerchowitzGregory P Copenhaver
Feb 21, 2006·Genetics·Deborah CharlesworthChunlao Tang
Jan 1, 2006·The Arabidopsis Book·Hong Ma
Mar 16, 2007·Proceedings of the National Academy of Sciences of the United States of America·Kirk E FrancisGregory P Copenhaver
Jun 20, 2014·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·E Sanchez-Moran, S J Armstrong

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
Kirk E FrancisG P Copenhaver
Proceedings of the National Academy of Sciences of the United States of America
R Scott Hawley
American Journal of Human Genetics
Elizabeth A Housworth, Franklin W Stahl
© 2021 Meta ULC. All rights reserved