PMID: 7520121Jan 1, 1994Paper

Assays of hemolytic toxins

Methods in Enzymology
G E Rowe, R A Welch

Abstract

The ability to produce a cytolytic toxin contributes to the success of many organisms in a particular niche by such diverse means as lysis of a phagolysosomal membrane of the macrophage by hemolysin from the intracellular parasite Trypanosoma cruzi, disruption of leukocyte activity by the Escherichia coli hemolysin, and destruction of invading bacteria by hemolysin from the annelid Glycera dibranchiata. The relative contribution of erythrocyte lysis to survival of the cytolysin producer is still under investigation. Nevertheless, the hemolytic phenotype is both a powerful tool for identifying novel cytolysins and a convenient marker for studying cytolytic activity in established toxins.

Citations

Jun 26, 1999·Molecular Microbiology·J OscarssonB E Uhlin
Aug 2, 2003·International Journal of Systematic and Evolutionary Microbiology·Ewald B M DennerLaurie L Richardson
Dec 4, 2009·Veterinary Research·Bodil Marie KristensenAnders Miki Bojesen
Sep 11, 2013·The Journal of Biological Chemistry·Monifa FahieMin Chen
Jul 15, 2015·Journal of Bacteriology·Elizabeth A HussaHeidi Goodrich-Blair
Nov 14, 2018·Infectious Diseases·Angelina Trifonova, Tanya Strateva
Jul 10, 2019·Frontiers in Microbiology·Marcela LeónRoberto Bastías
May 26, 2001·Applied and Environmental Microbiology·J BrillardA Givaudan
Sep 2, 2003·Journal of Bacteriology·Sun Nyunt WaiBernt Eric Uhlin
Jan 30, 2008·Microbiology·Stuart HuntJeffrey Green
Jan 3, 2006·Journal of Medical Microbiology·Paul W WhitbyTerrence L Stull
Nov 2, 2006·Molecular Microbiology·Charles E Cowles, Heidi Goodrich-Blair
Feb 6, 2010·Proceedings of the National Academy of Sciences of the United States of America·David J ChenDavid Putnam
Aug 10, 2017·Frontiers in Microbiology·Salih KumruAttila Karsi
Sep 28, 2000·The Journal of Biological Chemistry·A AtkinsJ Green
Sep 28, 2006·Cellular Microbiology·Youngjin ParkHeidi Goodrich-Blair
Jun 5, 2008·International Journal of Systematic and Evolutionary Microbiology·Xiang Y HanJonathan Segal
Dec 23, 2003·Letters in Applied Microbiology·Y V AlexeevaE P Ivanova
Sep 13, 2006·Letters in Applied Microbiology·P M S FigueirêdoT Yano
May 23, 2012·PLoS Pathogens·Guowei YangNicholas R Waterfield
Jul 20, 2010·Applied and Environmental Microbiology·Jiazhang QiuXuming Deng
Jan 17, 2014·Diseases of Aquatic Organisms·R Avendaño-HerreraA E Toranzo
May 24, 2012·Applied Biochemistry and Biotechnology·Sree Renjini IsacDurg Vijai Singh
Mar 2, 2018·Scientific Reports·Monifa A FahieMin Chen
Jul 10, 2020·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·K Keely BoyleThomas R Duquin
Oct 13, 2006·Letters in Applied Microbiology·S V AlavandiT C Santiago
Apr 18, 2009·The Journal of Antibiotics·Maxime GualtieriJacques-Olivier Thaler

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