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Brain Organoids in Disease Modeling
Brain organoids are three-dimensional cell culture models derived from human pluripotent stem cells. Since they resemble the embryonic brain, they can be used to help study brain biology, early brain development, and brain diseases. Discover the latest research on brain organoids in disease modeling here.
3D Cellular Models of Brain and Neurodegeneration
Brain organoids are three-dimensional in vitro cellular models of the brain that can recapitulate many processes such as the microenvironment and neurodevelopment. In addition, these organoids can be combined with other cell types, such as neurons and astrocytes to study their interactions in assembloids. Disease processes can also be modelled by induced pluripotent stem cell derived organoids and assembloids from patients with neurodegenerative disorders. Discover the latest research here.
Researcher Network:CZI Neurodegeneration Challenge
The Neurodegeneration Challenge Network aims to provide funding for and to bring together researchers studying neurodegenerative diseases. Find the latest research from the NDCN grantees here.